ChemicalBook > CAS DataBase List > 3-Chloro-4-methylpyridazine

3-Chloro-4-methylpyridazine

Product Name
3-Chloro-4-methylpyridazine
CAS No.
68206-04-2
Chemical Name
3-Chloro-4-methylpyridazine
Synonyms
3-CHLORO-4-METHYLPYRIDAZINE;3-Chloro-4-methyl-1,2-diazine;Pyridazine, 3-chloro-4-methyl-;3-Chloro-4-methylpyridazine97%;3-Chloro-4-methylpyridazine 97%;3-Chloro-4-methylpyridazine ISO 9001：2015 REACH
CBNumber
CB4848477
Molecular Formula
C5H5ClN2
Formula Weight
128.56
MOL File
68206-04-2.mol
More
Less

3-Chloro-4-methylpyridazine Property

Melting point:
46-47 °C
Boiling point:
254.7±20.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
1.54±0.10(Predicted)
color 
White
More
Less

Safety

HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C370916
Product name
3-Chloro-4-methylpyridazine
Packaging
1g
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC151278
Product name
3-Chloro-4-methylpyridazine
Packaging
500mg
Price
$205
Updated
2021/12/16
Matrix Scientific
Product number
083991
Product name
3-Chloro-4-methylpyridazine
Purity
97%
Packaging
1g
Price
$218
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-84
Product name
3-Chloro-4-methylpyridazine
Purity
95%
Packaging
1g
Price
$264
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC151278
Product name
3-Chloro-4-methylpyridazine
Packaging
1g
Price
$359
Updated
2021/12/16
More
Less

3-Chloro-4-methylpyridazine Chemical Properties,Usage,Production

Uses

3-Chloro-4-methylpyridazine is a useful intermediate for the synthesis of pesticides and anti-viral drugs.

Synthesis

33471-40-8

68206-04-2

General procedure for the synthesis of 3-chloro-4-methylpyridazine from 4-methyl-3(2H)-pyridazinone: The product of step c) (12.2 g, 0.112 mol) was dissolved in phosphorochloridic acid chloride (125 mL) and heated to reflux for 3 hours at 90 °C. Upon completion of the reaction, the reaction mixture was cooled to room temperature and concentrated to near dryness under reduced pressure. The concentrated residue was carefully poured into an ice/water mixture and the pH was adjusted to basic by slowly adding 4N NaOH solution. Subsequently, extraction was carried out with ether and the aqueous phase was then subjected to a secondary extraction with dichloromethane (DCM). All organic phases were combined, washed with water, dried over anhydrous sodium sulfate, filtered and concentrated to dryness under reduced pressure. Finally, the residue was purified by rapid chromatography on silica gel with 2:1 ethyl acetate-isohexane as eluent to give an orange solid product (11.2 g, 78% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.97 (1H, d, J = 4.9 Hz), 7.35 (1H, d, J = 4.9 Hz), 2.44 (3H, s) ppm.

References

[1] Patent: WO2004/74290, 2004, A1. Location in patent: Page 79
[2] Pharmaceutical Bulletin, 1957, vol. 5, p. 229,233
[3] Journal of Medicinal Chemistry, 1987, vol. 30, # 2, p. 239 - 249

3-Chloro-4-methylpyridazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Chloro-4-methylpyridazine Suppliers

China 108 Germany 1 India 1 Switzerland 1 United Kingdom 4 United States 15 Global 130
Xinxiang Anqi Biotechnology Co., Ltd
Tel
15036601220
Email
877180706@qq.com
Country
China
ProdList
50
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
918
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3731
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.
Tel
19943855286
Fax
0371-53392065
Email
triz-4@trizpharma.cn
Country
China
ProdList
1936
Advantage
56
Shanghai KaiYuLin pharmaceutical technology co., LTD
Tel
021-18721936-595 18721936595
Fax
-
Email
shkylpharma@126.com
Country
China
ProdList
736
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4894
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Huaxing Biological Technology Co., Ltd.
Tel
18621295758
Fax
-QQ:1449085402
Email
1449085402@qq.com
Country
China
ProdList
1817
Advantage
55
Nanjing Klender Bio-Technology Co., Ltd.
Tel
025-52343882 18112933882
Fax
025-52343882
Email
sales@kldbio.com
Country
China
ProdList
2019
Advantage
55
Shanghai Rlavie Technology Co., Ltd.
Tel
21-67759270 17717059219
Fax
QQ：1479352695
Email
sales@rlavie.com
Country
China
ProdList
1620
Advantage
55
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9751
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Shanghai Benso Pharmaceutical Technology Co., Ltd.
Tel
15088289376
Email
248775804@qq.com
Country
China
ProdList
4995
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9855
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
ROSEWA HOLDING GROUP CO.,LIMITED
Tel
+86-023-62871537
Email
sales@rosewachem.com
Country
China
ProdList
2803
Advantage
58
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
Finetech Industry Limited
Tel
+86-27-8746-5837 +8619945049750
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9629
Advantage
58
Shanghai Rlavie Technology Co ltd
Tel
+86-021-67759270 +8617717059219
Fax
021-67759270
Email
sales@rlavie.com
Country
China
ProdList
1030
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Hefei Hirisun Pharmatech Co., Ltd
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9911
Advantage
58
Shanghai TenSus Biotechnology Co., Ltd.
Tel
021-50895067 18616507272
Fax
021-50895067
Email
tensus@163.com
Country
China
ProdList
8073
Advantage
58
Shanghai Chuangtuo Biotechnology Co., Ltd.
Tel
021-64301660 18121334283
Email
sales@chuangtuobio.com
Country
China
ProdList
175
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
Zhengzhou Edward Biology Co.,Ltd
Tel
0371-63682289 15538176268
Fax
QQ：1875164801
Email
jacschem@163.com
Country
China
ProdList
9926
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Chengdu Feibo Pharm Technology Co., Ltd
Tel
+86 028-84641798 15982321820
Email
abby@arkpharm.com
Country
China
ProdList
10000
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
More
Less

View Lastest Price from 3-Chloro-4-methylpyridazine manufacturers

Dideu Industries Group Limited
Product
3-Chloro-4-methylpyridazine 68206-04-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-02
Career Henan Chemical Co
Product
3-Chloro-4-methylpyridazine 68206-04-2
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

68206-04-2, 3-Chloro-4-methylpyridazineRelated Search:

Tetramethylpyrazine Hydralazine Pyridazine Pyridaphenthion Thioridazine Sulfachloropyridazine sodium 2-Methylpyrazine Difluorochloromethane 3,6-Dichloro-4-methylpyridazine 3,6-Dichloropyridazine-4-carboxylic acid 1,4-DICHLORO-5,6,7,8-TETRAHYDRO-5,8-ETHANOPHTHALAZINE 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE 3,6-Dichloro-4,5-dimethylpyridazine 3-Chloro-5-methylpyridazine 97%,3-Chloro-5-methylpyridazine97%,3-Chloro-5-methylpyridazine N-BENZYL-6-CHLORO-N-METHYLPYRIDAZIN-3-AMINE 4,5-DICHLORO-2-METHYLPYRIDAZIN-3-ONE 6-Chloro-3-methylpyridazine,3-CHLORO-6-METHYLPYRIDAZINE,Chloro-6-methylpyridazine 4-Methylpyridazine

  • 3-CHLORO-4-METHYLPYRIDAZINE
  • 3-Chloro-4-methyl-1,2-diazine
  • 3-Chloro-4-methylpyridazine 97%
  • 3-Chloro-4-methylpyridazine97%
  • Pyridazine, 3-chloro-4-methyl-
  • 3-Chloro-4-methylpyridazine ISO 9001：2015 REACH
  • 68206-04-2
  • Pyridazine series
  • Pyrazines, Pyrimidines & Pyridazines
  • Building Blocks
  • Pyridazine
  • Halides
  • Pyrazines, Pyrimidines & Pyridazines