ChemicalBook > CAS DataBase List > Carboxymethoxylamine hemihydrochloride
Carboxymethoxylamine hemihydrochloride
- Product Name
- Carboxymethoxylamine hemihydrochloride
- CAS No.
- 2921-14-4
- Chemical Name
- Carboxymethoxylamine hemihydrochloride
- Synonyms
- AOA hcl (2:1);AOAhemihydrochloride;Carboxymethoxylamine-D2;aminooxyaceticacidhemichloride;AMinooxyacetic acid Hydrochloride;2-AMINOOXY-ACETICACIHYDROCHLORIDE;Carboxymethoxyamine·0.5hydrochloride;2-aminooxy-aceticacihydrochloride(2:1);(aminooxy)-aceticacihydrochloride(2:1);Aminyloxy-acetic Acid Hemihydrochlorid
- CBNumber
- CB4853440
- Molecular Formula
- C2H6ClNO3
- Formula Weight
- 127.53
- MOL File
- 2921-14-4.mol
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Carboxymethoxylamine hemihydrochloride Property
- Melting point:
- 156 °C (dec.)(lit.)
- Density
- 1.7848 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMF: 2mg/mL; DMSO: 5mg/mL; PBS (pH 7.2): 5mg/mL
- form
- Crystalline Powder or Crystals
- color
- White to off-white
- biological source
- synthetic (organic)
- Water Solubility
- decomposes
- BRN
- 3680528
- InChI
- InChI=1S/2C2H5NO3.ClH/c2*3-6-1-2(4)5;/h2*1,3H2,(H,4,5);1H
- InChIKey
- KBXIJIPYZKPDRU-UHFFFAOYSA-N
- SMILES
- C(ON)C(=O)O.C(ON)C(=O)O.Cl
- EPA Substance Registry System
- Acetic acid, (aminooxy)-, hydrochloride (2:1) (2921-14-4)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C13408
- Product name
- O-(Carboxymethyl)hydroxylamine hemihydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $97.85
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- C13408
- Product name
- O-(Carboxymethyl)hydroxylamine hemihydrochloride
- Purity
- 98%
- Packaging
- 10g
- Price
- $324
- Updated
- 2025/07/31
TCI Chemical
- Product number
- C0205
- Product name
- Carboxymethoxylamine Hemihydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $202
- Updated
- 2025/07/31
TCI Chemical
- Product number
- C0205
- Product name
- Carboxymethoxylamine Hemihydrochloride
- Purity
- >98.0%(T)
- Packaging
- 500g
- Price
- $2090
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 28298
- Product name
- Aminooxyacetic Acid (hydrochloride)
- Purity
- ≥95%
- Packaging
- 250mg
- Price
- $37
- Updated
- 2024/03/01
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Carboxymethoxylamine hemihydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder or crystals
Uses
Carboxymethoxylamine hemihydrochloride is a bifunctional linking reagent that undergoes condensation with aldehydes and ketones to form oximes. It can also be used as a potent inhibitor of (pyridoxal 5’-phosphate) PLP-dependent β-lyases.
Preparation
Carboxymethylhydroxylamine hemihydrochloride is obtained by reacting O-carboxymethylacetone oxime with hydrochloric acid.
Definition
ChEBI: (aminooxy)acetic acid hemihydrochloride is the hemihydrochloride salt of (aminooxy)acetic acid. It is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme 4-aminobutyrate aminotransferase and cystathionine beta-synthetase. It contains an (aminooxy)acetate.
in vivo
The accumulation of GABA in cerebellum and whole brain is initially very rapid, being significantly increased already 5 min after the injection of Aminooxyacetic acid hemihydrochloride (AOAA). The rapid initial accumulation becomes gradually slower and maximal levels (400 to 600 % of the control levels) are reached 2 to 6 h after Aminooxyacetic acid hemihydrochloride. Still 24 h after Aminooxyacetic acid hemihydrochloride the GABA levels are elevated by about 250%. From 2 to 6 h after Aminooxyacetic acid hemihydrochloride the convulsions are completely blocked. Twenty four hours after Aminooxyacetic acid hemihydrochloride the convulsions are almost identical to the controls[2].
Carboxymethoxylamine hemihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Carboxymethoxylamine hemihydrochloride manufacturers
Honest Joy Holdings Limited
- Product
- Carboxymethoxylaminehemihydrochloride 2921-14-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.9%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
Unipharm pharmaceutical industry Co., Ltd
- Product
- Carboxymethoxylamine hemihydrochloride 2921-14-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- EX: 100kgs
- Release date
- 2021-03-24
Nanjing jinheyou Trading Co., Ltd.
- Product
- Carboxymethoxylamine hemihydrochloride 2921-14-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 99.5%min
- Supply Ability
- 20kg/week
- Release date
- 2019-10-29
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