4-Fluorobenzoic acid

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4-Fluorobenzoic acid

Description Reference

Product Name: 4-Fluorobenzoic acid
CAS No.: 456-22-4
Chemical Name: 4-Fluorobenzoic acid
Synonyms: PFBA;P-FLUOROBENZOIC ACID;potassium 2,2,3,3,3-pentafluoropropanoate;4-fluoro-benzoicaci;The acid;AKOS 92636;p-Fluorobenzoic;fluorobenzoicacid;Fluoro benzoic ac;4-Fluorbenzoesure
CBNumber: CB4853637
Molecular Formula: C7H5FO2
Formula Weight: 140.11
MOL File: 456-22-4.mol

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4-Fluorobenzoic acid Property

Melting point:: 182-184 °C (lit.)
Boiling point:: 117 °C
Density: 1.479
storage temp.: Sealed in dry,Room Temperature
solubility: alcohol: soluble
form: Crystalline Powder
pka: 4.15(at 25℃)
color: White to slightly yellow
Water Solubility: Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water.
Merck: 14,4171
BRN: 1906922
InChIKey: BBYDXOIZLAWGSL-UHFFFAOYSA-N
CAS DataBase Reference: 456-22-4(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-fluoro-(456-22-4)
EPA Substance Registry System: Benzoic acid, 4-fluoro- (456-22-4)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-41-36/37/38
Safety Statements: 26-39-24/25-22-37/39-36
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT
HS Code: 29163900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 128384
Product name: 4-Fluorobenzoic acid
Purity: 98%
Packaging: 5g
Price: $17.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 128384
Product name: 4-Fluorobenzoic acid
Purity: 98%
Packaging: 25g
Price: $35
Updated: 2024/03/01

TCI Chemical

Product number: F0112
Product name: 4-Fluorobenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $47
Updated: 2024/03/01

Alfa Aesar

Product number: A14129
Product name: 4-Fluorobenzoic acid, 98%
Packaging: 25g
Price: $34.4
Updated: 2024/03/01

Alfa Aesar

Product number: A14129
Product name: 4-Fluorobenzoic acid, 98%
Packaging: 100g
Price: $77.65
Updated: 2024/03/01

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4-Fluorobenzoic acid Chemical Properties,Usage,Production

Description

4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the ¹⁸F labeling of antibodies. It has been used in high resolution charge density study.

Reference

AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorobenzoic acid has been used in high resolution charge density study.

Definition

ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.

Purification Methods

Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]

4-Fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Benzocaine Ethyl 4-fluorobenzoate 4-Fluorobenzaldehyde Fluoroboric acid STANDARD BUFFER

Preparation Products

Lomefloxacin 4-Fluorobenzoyl chloride (4-(4-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZIN-1-YL)PHENYL)METHANOL

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View Lastest Price from 4-Fluorobenzoic acid manufacturers

Speranza Chemical Co., Ltd.

Product: 4-Fluorobenzoic acid 456-22-4
Price: US $15.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 300MT/year
Release date: 2019-12-24

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 4-Fluorobenzoic acid 456-22-4
Price: US $40.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-30

Shanghai UCHEM Inc.

Product: 4-Fluorobenzoic acid 456-22-4
Price: US $38.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100kg
Release date: 2023-10-30

456-22-4, 4-Fluorobenzoic acidRelated Search:

4-Fluorobenzonitrile Stearic acid 4-Bromofluorobenzene Folic acid 4-Fluorobenzamide 4-Fluorobenzaldehyde 4-Fluoroanisole Florfenicol 4-(4-Fluorobenzoyl)butyric acid Methyl 4-fluorobenzoate 2,6-Difluorobenzoic acid Ethyl 4-fluorobenzoate Transfluthrin Ethyl 2-(Chlorosulfonyl)acetate 2,4,5-Trifluorobenzoic acid Citric acid 4-Fluorobenzyl alcohol Ascoric Acid

4-FLUOROBENZOIC ACID

AKOS 92636

4-fluoro-benzoicaci

Benzoic acid, p-fluoro-

Benzoicacid,4-fluoro-

fluorobenzoicacid

para-Fluorobenzoic acid

p-Fluorobenzoic Acid 4-Fluorobenzoic Acid

4-Fluorobenzoi acid

4-FLUOROBENZOIC ACID, SUBLIMED, 99%

4-FLUOROBENZOIC ACID, FOR ELEMENTAL ANALYSIS

P-FLUOROBENZOIC ACID GRADE I

4-Fluorobenzoicacid,98%

PFBA

P-FLUOROBENZOIC ACID

TIMTEC-BB SBB008568

RARECHEM AL BO 0053

potassium 2,2,3,3,3-pentafluoropropanoate

p-Fluorobenzoic

p-Fluorobenzoicacid,min.97%

4-Fluorobenzoic acid ,99%

p-Fluorobenzoic acid, min. 97%

4-Fluorobenzoic acid, 99% 25GR

4-FLUOROBENZOIC ACID FOR SYNTHESIS

Fluoro benzoic ac

The acid

4-Fluorobenzoic acid 99%, purified by sublimation

Haloperidol Impurity 14

4-FluorobenzoicAcid&gt

4-Fluorbenzoesure

4-Fluorobenzoic Acid pure, 98%

456-22-4

FC6H4COOH

Organic Building Blocks

Carbonyl Compounds

Carboxylic Acids

Building Blocks

CARBOXYLIC ACID

carboxylic acid| alkyl Fluorine

Carboxylic Acids

Phenyls & Phenyl-Het

Carbonyl Compounds

Benzene derivatives

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Carboxylic Acids

Phenyls & Phenyl-Het

Fluorobenzene

API intermediates

Fluorin-contained Benzoic acid series

bc0001