4-Fluorobenzoic acid
Description Reference- Product Name
- 4-Fluorobenzoic acid
- CAS No.
- 456-22-4
- Chemical Name
- 4-Fluorobenzoic acid
- Synonyms
- PFBA;P-FLUOROBENZOIC ACID;potassium 2,2,3,3,3-pentafluoropropanoate;4-fluoro-benzoicaci;The acid;AKOS 92636;p-Fluorobenzoic;fluorobenzoicacid;Fluoro benzoic ac;4-Fluorbenzoesure
- CBNumber
- CB4853637
- Molecular Formula
- C7H5FO2
- Formula Weight
- 140.11
- MOL File
- 456-22-4.mol
4-Fluorobenzoic acid Property
- Melting point:
- 182-184 °C (lit.)
- Boiling point:
- 117 °C
- Density
- 1.479
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- alcohol: soluble
- form
- Crystalline Powder
- pka
- 4.15(at 25℃)
- color
- White to slightly yellow
- Water Solubility
- Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water.
- Merck
- 14,4171
- BRN
- 1906922
- InChIKey
- BBYDXOIZLAWGSL-UHFFFAOYSA-N
- CAS DataBase Reference
- 456-22-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 4-fluoro-(456-22-4)
- EPA Substance Registry System
- Benzoic acid, 4-fluoro- (456-22-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-41-36/37/38
- Safety Statements
- 26-39-24/25-22-37/39-36
- WGK Germany
- 3
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 128384
- Product name
- 4-Fluorobenzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $17.8
- Updated
- 2024/03/01
- Product number
- 128384
- Product name
- 4-Fluorobenzoic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $35
- Updated
- 2024/03/01
- Product number
- F0112
- Product name
- 4-Fluorobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $47
- Updated
- 2024/03/01
- Product number
- A14129
- Product name
- 4-Fluorobenzoic acid, 98%
- Packaging
- 25g
- Price
- $34.4
- Updated
- 2024/03/01
- Product number
- A14129
- Product name
- 4-Fluorobenzoic acid, 98%
- Packaging
- 100g
- Price
- $77.65
- Updated
- 2024/03/01
4-Fluorobenzoic acid Chemical Properties,Usage,Production
Description
4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the 18F labeling of antibodies. It has been used in high resolution charge density study.
Reference
AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356
Chemical Properties
white to light yellow crystal powder
Uses
4-Fluorobenzoic acid has been used in high resolution charge density study.
Definition
ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.
Purification Methods
Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]
4-Fluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Fluorobenzoic acid Suppliers
- Tel
- +91-22-26355700
- Fax
- +91-22-26355701
- info@clearsynth.com
- Country
- India
- ProdList
- 9685
- Advantage
- 58
- Tel
- +918790379245
- banny.janga@btcpharm.com
- Country
- India
- ProdList
- 1269
- Advantage
- 58
View Lastest Price from 4-Fluorobenzoic acid manufacturers
- Product
- 4-Fluorobenzoic acid 456-22-4
- Price
- US $15.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 300MT/year
- Release date
- 2019-12-24
- Product
- 4-Fluorobenzoic acid 456-22-4
- Price
- US $9.00-0.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-23
- Product
- 4-Fluorobenzoic acid 456-22-4
- Price
- US $38.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100kg
- Release date
- 2023-10-30