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Penicillin G potassium salt

Product Name
Penicillin G potassium salt
CAS No.
113-98-4
Chemical Name
Penicillin G potassium salt
Synonyms
PENICILLIN G POTASSIUM;BENZYLPENICILLIN POTASSIUM;PENICILLIN G POTASSIUM SALT;PENICILLIN G POTASSIUM SALT;pfizerpen;Penicilline G;potassium [2s-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Pen-G;forpen;PENICILLINE G POTASSIUM
CBNumber
CB4855484
Molecular Formula
C16H17KN2O4S
Formula Weight
372.48
MOL File
113-98-4.mol
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Penicillin G potassium salt Property

Melting point:
214-217 C
alpha 
D22 +285° (c = 0.748 in water)
refractive index 
294 ° (C=1, H2O)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
H2O: 100 mg/mL
form 
powder
color 
Needles from butanol (aq)
PH
pH (10g/L, 25℃) : 5.0～7.5
Water Solubility 
Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Merck 
14,7094
BRN 
3832841
Stability:
Hygroscopic
InChIKey
IYNDLOXRXUOGIU-LQDWTQKMSA-M
SMILES
N12C([C@@H](NC(=O)CC3=CC=CC=C3)[C@@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O.[K+] |&1:2,13,19,r|
EPA Substance Registry System
Penicillin G Potassium (113-98-4)
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Safety

Hazard Codes 
Xn,C,F
Risk Statements 
42/43-34-11
Safety Statements 
36/37-45-36/37/39-26-16-60-37-24-22
WGK Germany 
2
RTECS 
XH9700000
F 
10-23
TSCA 
Yes
HS Code 
29411000
Toxicity
LD50 oral in rabbit: 5848mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PENK
Product name
Penicillin G potassium salt
Purity
~1600?U/mg
Packaging
1000000units
Price
$21.9
Updated
2024/03/01
Sigma-Aldrich
Product number
PENK
Product name
Penicillin G potassium salt
Purity
~1600?U/mg
Packaging
10000000units
Price
$27.8
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2640
Product name
Penicillin G Potassium
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500MG
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
PENK
Product name
Penicillin G potassium salt
Purity
~1600?U/mg
Packaging
100000000units
Price
$130
Updated
2024/03/01
Sigma-Aldrich
Product number
P7794
Product name
Penicillin G potassium salt
Purity
powder, BioReagent, suitable for cell culture
Packaging
1000000units
Price
$22.5
Updated
2024/03/01
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Penicillin G potassium salt Chemical Properties,Usage,Production

Description

Benzylpenicillin potassiumwas the first crystalline penicillin produced on an industrial scale , . It is produced in the pure state by the addition of phenylacetate to a culture of Penicillium chrysogenum. The crystalline benzylpenicillin potassium contains 1598 U/mg.

Chemical Properties

Penicillin G potassium salt is also known as Potassium benzylpenicillin, it is white crystalline powder, odorless or slightly specific odor, hygroscopic. Soluble in water, physiological saline, glucose solution. The aqueous solution of it is easy to fail when placed at room temperature, and it will fail rapidly in the presence of acid, alkali, oxidant, etc. Penicillin G potassium salt has good antibacterial effect on Streptococcus such as Streptococcus hemolyticus, Streptococcus pneumoniae and Staphylococcus without penicillinase.

Uses

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Preparation

Penicillin G potassium salt is a highly effective and low toxicity antibiotic, which is obtained by salt formation of Chlorpheniramine maleate and maleic acid.

Definition

ChEBI: Penicillin G potassium salt is organic potassium salt of benzylpenicillin. It is an antibiotic substance produced by Penicillium sp. Antibacterial. It contains a benzylpenicillin(1-).

brand name

Pentids (Apothecon); Pfizerpen (Pfizer).

General Description

Penicillin G Potassium is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G potassium binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, which is a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Safety Profile

Poison by intracerebral andintravenous routes. Moderately toxic by intraperitonealroute. Mutation data reported. See other penicillin entries.When heated to decomposition it emits toxic fumes ofNOx and SOx.

Penicillin G potassium salt Preparation Products And Raw materials

Raw materials

D(+)-Glucose Ethanol Potassium carbonate Butyl acetate 1-Butanol Phenylacetic acid

Preparation Products

Calcium gluconate Procaine penicillin G Cephalexin 6-Aminopenicillanic acid D-Penicillamine Pivaloyloxymethyl6-(phenylacetamido)penicillanate Penicillin G sodium salt
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Penicillin G potassium salt Suppliers

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View Lastest Price from Penicillin G potassium salt manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.
Product
Penicillin G potassium salt 113-98-4
Price
US $0.00/bou
Min. Order
40bou
Purity
≥96%
Supply Ability
10000bou
Release date
2024-04-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Potassium benzylpenicillin 113-98-4
Price
US $1.00/KG
Min. Order
1KG
Purity
≥96.0%
Supply Ability
1000kg/month
Release date
2021-06-21
shandong perfect biotechnology co.ltd
Product
Penicillin G potassium 113-98-4
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
100kg
Release date
2023-08-08

113-98-4, Penicillin G potassium saltRelated Search:

Sodium 1-heptanesulfonate Potassium iodide Heptane Potassium Acetate Potassium chloride Potassium sorbate Potassium persulfate Potassium Citrate Potassium bromate PENITREM A D-Penicillamine Penicillin G sodium salt Carbenicillin Disodium Salt Potassium nitrate Potassium Penicillin G PHENETHICILLIN POTASSIUM SALT AMOXYCILLIN SODIUM/POTASSIUM CLAVULANATE Benzylpenicillin Potassium

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  • = 97% PURE WITH HPLC RADIOCHROMATOGRAM
  • BENZYLPENICILLIN POTASSIUM, [ACETAMIDO-1,2-14C]- 50-60 MCI(1.85-2.22 GBQ)/MMOL, HPLC PURIFIED, DELIVERED &gt