Tacalcitol
- Product Name
- Tacalcitol
- CAS No.
- 57333-96-7
- Chemical Name
- Tacalcitol
- Synonyms
- TV 02;C12919;Bonalfa;PRI 2191;Tacalcital;Tacalcitol;Curatoderm;Tacalcitol RS;trans-Calcitriol;1α,24R-Dihydroxyvitamin D3
- CBNumber
- CB4875440
- Molecular Formula
- C27H44O3
- Formula Weight
- 416.64
- MOL File
- 57333-96-7.mol
Tacalcitol Property
- Boiling point:
- 565.0±50.0 °C(Predicted)
- Density
- 1.06
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- 20mg/mL in DMSO, 20mg/mL in DMF, 20mg/mL in Ethanol
- pka
- 14.43±0.40(Predicted)
- form
- Powder
- CAS DataBase Reference
- 57333-96-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SMB00579
- Product name
- Tacalcitol
- Purity
- ≥99% (HPLC)
- Packaging
- 1MG
- Price
- $309
- Updated
- 2024/03/01
- Product number
- 12079
- Product name
- 1,24-dihydroxy Vitamin D3
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $169
- Updated
- 2021/12/16
- Product number
- 12079
- Product name
- 1,24-dihydroxy Vitamin D3
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $89
- Updated
- 2021/12/16
- Product number
- 12079
- Product name
- 1,24-dihydroxy Vitamin D3
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $712
- Updated
- 2021/12/16
- Product number
- T004005
- Product name
- Tacalcitol
- Packaging
- 1mg
- Price
- $320
- Updated
- 2021/12/16
Tacalcitol Chemical Properties,Usage,Production
Description
Tacalcitol, the second vitamin D analog developed as a topical antipsoriatic, was introduced for keratosis, psoriasis, ichthyosis, pityriasis rubra pilaris and palmoplantar pustulosis and keratoderma. It shows improvement in appearance of skin lesions for psoriasis patients without significant side effects. In patients with psoriasis vulgaris, it effectively inhibits keratinocyte growth. Some in vitro studies have shown that tacalcitol inhibits interleukin-1-α-induced granulocyte macrophage colony-stimulating-factor mRNA expression of the human dermal microvascular endothelial cells, which may be involved in mediation of angioproliferation in skin inflammation.
Originator
Teijin (Japan)
Uses
Tacalcitol is a synthetic vitamin D3 analog.
Definition
ChEBI: Tacalcitol is a hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp. It has a role as an antipsoriatic, a vitamin D receptor agonist and an antineoplastic agent. It is a member of D3 vitamins, a hydroxy seco-steroid, a secondary alcohol and a seco-cholestane. It is functionally related to a calciol.
brand name
Bonalfa
Safety Profile
A poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors,
Tacalcitol Preparation Products And Raw materials
Raw materials
Preparation Products
Tacalcitol Suppliers
- Tel
- +91-22-26355700
- Fax
- +91-22-26355701
- info@clearsynth.com
- Country
- India
- ProdList
- 9685
- Advantage
- 58
View Lastest Price from Tacalcitol manufacturers
- Product
- Tacalcitol 57333-96-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%min. HPLC
- Supply Ability
- 1000kg
- Release date
- 2022-11-07
- Product
- Tacalcitol 57333-96-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Tacalcitol 57333-96-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08