4-Iodo-2-methylpyridine
- Product Name
- 4-Iodo-2-methylpyridine
- CAS No.
- 22282-65-1
- Chemical Name
- 4-Iodo-2-methylpyridine
- Synonyms
- 4-Iodo-2-methylpyridine;Pyridine, 4-iodo-2-methyl-;4-Iodo-2-methylpyridine ISO 9001:2015 REACH
- CBNumber
- CB4967480
- Molecular Formula
- C6H6IN
- Formula Weight
- 219.02
- MOL File
- 22282-65-1.mol
4-Iodo-2-methylpyridine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B448828
- Product name
- 4-Iodo-2-methylpyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-W018720
- Product name
- 4-Iodo-2-methylpyridine
- Purity
- 97.68%
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 118958
- Product name
- 4-Iodo-2-methylpyridine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $144
- Updated
- 2021/12/16
- Product number
- 3H32-H-65
- Product name
- 4-Iodo-2-methylpyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $148
- Updated
- 2021/12/16
- Product number
- CS-W018720
- Product name
- 4-Iodo-2-methylpyridine
- Purity
- 97.68%
- Packaging
- 5g
- Price
- $312
- Updated
- 2021/12/16
4-Iodo-2-methylpyridine Chemical Properties,Usage,Production
Synthesis
3678-63-5
22282-65-1
General procedure for the synthesis of 2-methyl-4-iodopyridine from 4-chloro-2-methylpyridine: 4-chloro-2-methylpyridine (10 g, 78 mmol), sodium iodide (17.8 g, 118 mmol), and hydriodic acid (57%, 26 mL, 196 mmol) were heated and reacted in a sealed tube for 7 days at 140 °C. Upon completion of the reaction, the reaction mixture was slowly poured into ice water and neutralized with sodium hydroxide solution. Subsequently, the mixture was extracted three times with dichloromethane (300 mL each time). The organic phases were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure. The resulting product was an off-white solid (14.7 g, 85% yield) and could be used in subsequent reactions without further purification.
References
[1] Patent: WO2004/80998, 2004, A1. Location in patent: Page 27
[2] Patent: US2002/40040, 2002, A1
[3] Chemical & Pharmaceutical Bulletin, 1982, vol. 30, # 5, p. 1731 - 1737
4-Iodo-2-methylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Iodo-2-methylpyridine manufacturers
- Product
- 4-Iodo-2-methylpyridine 22282-65-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-01