2-BROMO-ISONICOTINIC ACID METHYL ESTER
- Product Name
- 2-BROMO-ISONICOTINIC ACID METHYL ESTER
- CAS No.
- 26156-48-9
- Chemical Name
- 2-BROMO-ISONICOTINIC ACID METHYL ESTER
- Synonyms
- METHYL 2-BROMOISONICOTINATE;2-BROMO-4-METHYL PICOLINATE;Methyl 2-bromopyridine-4-carboxylate;RARECHEM AL BF 1524;2-Bromopyridine -4-carboxyli;Methyl2-Bromoisonicotinate>Methyl 2-bromoisonicotinate 98%;methyl 2-bromo-4-pyridinecarboxylate;2-BROMO-ISONICOTINIC ACID METHYL ESTER;2-Bromopyridine-4-Picolinic acid methyl ester
- CBNumber
- CB5102932
- Molecular Formula
- C7H6BrNO2
- Formula Weight
- 216.03
- MOL File
- 26156-48-9.mol
2-BROMO-ISONICOTINIC ACID METHYL ESTER Property
- Melting point:
- 35-36
- Boiling point:
- 268.0±20.0 °C(Predicted)
- Density
- 1.579±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- -1.32±0.10(Predicted)
- color
- White to Light yellow
- BRN
- 128656
- InChIKey
- MULLTHQTADMZDM-UHFFFAOYSA-N
- CAS DataBase Reference
- 26156-48-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 689505
- Product name
- Methyl 2-bromopyridine-4-carboxylate
- Purity
- 95%
- Packaging
- 5g
- Price
- $105
- Updated
- 2022/05/15
- Product number
- 689505
- Product name
- Methyl 2-bromopyridine-4-carboxylate
- Purity
- 95%
- Packaging
- 1g
- Price
- $134
- Updated
- 2022/05/15
- Product number
- M2461
- Product name
- Methyl 2-Bromoisonicotinate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $109
- Updated
- 2025/07/31
- Product number
- M2461
- Product name
- Methyl 2-Bromoisonicotinate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $327
- Updated
- 2025/07/31
- Product number
- M296138
- Product name
- Methyl 2-Bromoisonicotinate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
2-BROMO-ISONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production
Chemical Properties
Colorless liquid or solid
Uses
2-Bromopyridine-4-carboxylic acid methyl ester is a kind of important medicine intermediate, used as initiator during the synthesis of polymer brushes with single-walled carbon nanotubes as backbones.
Synthesis
67-56-1
66572-56-3
26156-48-9
To a 250 mL round bottom flask was added a methanol (100 mL) solution of 2-bromo-4-pyridinecarboxylic acid (10 g, 49.50 mmol, 1.00 equiv) and concentrated sulfuric acid (98%, 5 mL). The reaction mixture was stirred at 70 °C overnight. Upon completion of the reaction, the solution was concentrated under reduced pressure to remove the solvent. The residue was dissolved in 200 mL of ethyl acetate (EtOAc) and washed with saturated sodium bicarbonate solution (3 x 150 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and the filtrate was concentrated under reduced pressure to give 10 g (94% yield) of methyl 2-bromopyridine-4-carboxylate as a colorless oil.
References
[1] Patent: WO2016/138335, 2016, A1. Location in patent: Paragraph 00319
[2] Patent: WO2016/34675, 2016, A1. Location in patent: Page/Page column 69
[3] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 18
[4] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 37
[5] Journal of Organic Chemistry, 2009, vol. 74, # 19, p. 7441 - 7448
2-BROMO-ISONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-ISONICOTINIC ACID METHYL ESTER manufacturers
- Product
- 2-BROMO-ISONICOTINIC ACID METHYL ESTER 26156-48-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
- Product
- Methyl 2-bromopyridine-4-carboxylate 26156-48-9
- Price
- US $88.00-467.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 10kg
- Release date
- 2023-11-14
- Product
- 2-BROMO-ISONICOTINIC ACID METHYL ESTER 26156-48-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08