2-Bromopyridine-4-carboxylic acid
- Product Name
- 2-Bromopyridine-4-carboxylic acid
- CAS No.
- 66572-56-3
- Chemical Name
- 2-Bromopyridine-4-carboxylic acid
- Synonyms
- 2-BROMOISONICOTINIC ACID;RARECHEM AL BE 1524;IFLAB-BB F1926-0035;2-BroMoisonicotinic;2-Bromopyridine-4-ca;2-bromoisonicotic acid;2-bromo-4-piconlic acid;2-bromo-4-picolinic acid;2-BroMo-4-carboxy-pyridine;2-Bromopyridine-4-carboxyL
- CBNumber
- CB3147405
- Molecular Formula
- C6H4BrNO2
- Formula Weight
- 202.01
- MOL File
- 66572-56-3.mol
2-Bromopyridine-4-carboxylic acid Property
- Melting point:
- 229-231°C
- Boiling point:
- 447.2±30.0 °C(Predicted)
- Density
- 1.813±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 2.98±0.10(Predicted)
- form
- Crystals or Crystalline Powder
- color
- White
- BRN
- 471895
- InChI
- InChI=1S/C6H4BrNO2/c7-5-3-4(6(9)10)1-2-8-5/h1-3H,(H,9,10)
- InChIKey
- YBTKGKVQEXAYEM-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=CC(C(O)=O)=C1
- CAS DataBase Reference
- 66572-56-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-36/37
- WGK Germany
- 3
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- IRRITANT
- HS Code
- 29333990
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 703990
- Product name
- 2-Bromopyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $92.45
- Updated
- 2025/07/31
- Product number
- 703990
- Product name
- 2-Bromopyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $48
- Updated
- 2023/06/20
- Product number
- B3368
- Product name
- 2-Bromoisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- B3368
- Product name
- 2-Bromoisonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $71
- Updated
- 2025/07/31
- Product number
- B687923
- Product name
- 2-Bromoisonicotinic Acid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
2-Bromopyridine-4-carboxylic acid Chemical Properties,Usage,Production
Chemical Properties
White to light brown powder
Uses
2-Bromoisonicotinic acid (CAS 66572-56-3) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Application
2-Bromopyridine-4-carboxylic acid is a kind of Pyridine carboxylic acid compounds, it can be used in medicine synthesis.
Hazard
2-Bromopyridine-4-carboxylic acid is irritating to the eyes and skin, and may also cause respiratory tract irritation.
Health Hazard
Accidental contact with 2-Bromopyridine-4-carboxylic acid causes skin irritation and serious eye irritation.
Synthesis
4926-28-7
66572-56-3
General procedure for the synthesis of 2-bromo-4-pyridinecarboxylic acid from 2-bromo-4-methylpyridine: To a stirred solution of 29.0 g (69 mmol) of 2-bromo-4-methylpyridine dissolved in 150 mL of concentrated sulfuric acid was added batchwise 67.9 g (231 mmol) of potassium dichromate. The reaction was cooled using an ice bath to maintain a constant temperature. After addition, the reaction mixture was continued to be stirred at room temperature for 2 hours. Subsequently, the reaction mixture was slowly poured into 2 L of ice water and stirred at room temperature for 1 hour. The resulting crystals were collected by filtration, washed with water until the eluent was colorless, and finally dried under vacuum to give 30.0 g (88% yield) of 2-bromo-4-pyridinecarboxylic acid.
References
[1] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 17; 18
[2] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 36; 37
[3] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[4] Patent: US2008/51397, 2008, A1. Location in patent: Page/Page column 9; 24
[5] Polyhedron, 2016, vol. 118, p. 159 - 170
2-Bromopyridine-4-carboxylic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Bromopyridine-4-carboxylic acid manufacturers
- Product
- 2-Bromopyridine-4-carboxylic acid 66572-56-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-22
- Product
- 2-Bromopyridine-4-carboxylic acid 66572-56-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-05
- Product
- 2-Bromopyridine-4-carboxylic acid 66572-56-3
- Price
- US $3.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-26