Asiatic acid

Product Name: Asiatic acid
CAS No.: 464-92-6
Chemical Name: Asiatic acid
Synonyms: 2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID;NSC 166063;ASIATIC ACID;Asiantic acid;ASIATICA ACID;ASIATIC ACID(P);DaMMarolic acid;Asiatic acid-RM;Asiatic Acid >Snow oxalic acid
CBNumber: CB5109340
Molecular Formula: C30H48O5
Formula Weight: 488.7
MOL File: 464-92-6.mol

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Asiatic acid Property

Melting point:: 325-330 °C(lit.)
Boiling point:: 609.4±55.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
RTECS: YU9580000
storage temp.: 2-8°C
solubility: methanol: soluble1mg/mL, clear, colorless
form: powder
pka: 4.66±0.70(Predicted)
color: white
biological source: Centella asiatica
Water Solubility: Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
InChIKey: JXSVIVRDWWRQRT-UYDOISQJSA-N
LogP: 5.748 (est)
CAS DataBase Reference: 464-92-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
WGK Germany: 3
HS Code: 29181990
Hazardous Substances Data: 464-92-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 89773
Product name: Asiatic acid
Purity: analytical standard
Packaging: 10mg
Price: $460
Updated: 2025/07/31

Sigma-Aldrich

Product number: 546712
Product name: Asiatic acid
Purity: 97%
Packaging: 500mg
Price: $267.9
Updated: 2025/07/31

TCI Chemical

Product number: A2475
Product name: Asiatic Acid
Packaging: 200MG
Price: $95
Updated: 2025/07/31

Cayman Chemical

Product number: 11818
Product name: Asiatic Acid
Purity: ≥95%
Packaging: 50mg
Price: $41
Updated: 2024/03/01

Cayman Chemical

Product number: 11818
Product name: Asiatic Acid
Purity: ≥95%
Packaging: 500mg
Price: $183
Updated: 2024/03/01

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Asiatic acid Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the whole grass of Centella asiatica (Centella asiatica), a plant of the genus Leiogangen, family Umbelliferae.

Uses

wound healing, experimental carcinogen

Uses

Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.

Uses

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.

Definition

ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity.

General Description

Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.

Biochem/physiol Actions

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.

Synthesis

16830-15-2

464-92-6

1) 1 g of (2α,3β,4α)-3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-hexamethyl- Eicosanoid-4a-carboxylic acid ester (asiaticoside), 4.3×10^-2 mol sodium dodecyl sulfate and 0.02 mol NaOH were mixed, water was added to 1 L, and stirred until completely dissolved to obtain a mixed solution. The hydrolysis reaction was carried out at room temperature (25°C) and atmospheric pressure (1 atm) for 15 min to obtain the hydrolysate.2) The pH of the hydrolysate was adjusted to 5.0 with 1 M HCl solution and allowed to stand for 30 min, followed by filtration and collection of the precipitate.3) The precipitate was dissolved in 70% (v/v) aqueous ethanol at a ratio of 1 g:30 mL and filtered to remove insoluble matter. Crystallization was carried out by adding 16 times the volume of distilled water to the filtrate and allowed to stand overnight for complete crystallization. The crystallized product was collected by filtration and dried to constant weight in a vacuum drying oven at 40°C to obtain cumaric acid white crystals of 0.445 g. The product was analyzed by high-performance liquid chromatography (HPLC) with a purity of 95.8% and a yield of 93.08%.

target

References

[1] Patent: CN106349319, 2017, A. Location in patent: Paragraph 0017-0032
[2] Patent: WO2009/89365, 2009, A2. Location in patent: Page/Page column 6-7
[3] Steroids, 2015, vol. 96, p. 44 - 49
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 20, p. 4500 - 4504
[5] RSC Advances, 2016, vol. 6, # 67, p. 62890 - 62906

Asiatic acid Preparation Products And Raw materials

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Preparation Products

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View Lastest Price from Asiatic acid manufacturers

Shaanxi Xianhe Biotech Co., Ltd

Product: Asiatic acid 464-92-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-28

Hebei Chuanghai Biotechnology Co., Ltd

Product: Asiatic acid 464-92-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-10

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Asiatic Acid 464-92-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-09

464-92-6, Asiatic acidRelated Search:

Citric acid Shikimic acid Calcium oxalate Ammonium oxalate monohydrate Dimethyl oxalate Ferrous oxalate Ethyl 2-(Chlorosulfonyl)acetate Hyaluronic acid Folic acid Ascoric Acid Madecassic acid niga-ichigoside F1 Asiatic acid Centella asiatica whole plant ASIATIC ACID 95% 2,3,23-TRI(ACETYLOXY)-(2ALPHA,3BETA,4ALPHA)-URS-12-EN-28-OIC ACID ASIATIC ACID(RG) 2,3,23-TRI(ACETYLOXY)-(2ALPHA,3BETA,4ALPHA)-URS-12-EN-28-OIC ACID METHYL ESTER

2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID

(1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid

ASIATIC ACID

URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-

ASIATIC ACID(P)

Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-

ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,

2α,3β,23-Trihydroxyurs-12-en-28-oicacid

(4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid

2α,3β,23-Trihydroxyurs-12-ene-28-oic acid

Asiantic acid

10,11-dihydroxy-9-(hydroxyMethyl)-1,2,6a,6b,9,12a-hexaMethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid

(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid

ASIATICA ACID

DaMMarolic acid

Asiatic acid (1S,2R,4aS,6aR,6aS,6bR,8aR,9S,10S,11R,12aS,14bR)-10,11-Dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

2α,23-Dihydroxyursolic acid

NSC 166063

Asiatic Acid &gt

Asiatic acid (AA)

2alpha,23-Dihydroxyursolic Acid

2alpha,3beta,23-Trihydroxy-12-ursen-28-oic Acid

Asiatic acid USP/EP/BP

(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

Asiatic Acid (Dammarolic acid, Asiantic acid)

Asiatic Acid pure, 97%

Asiatic acid, 97%,

Asiatic acid (6CI)

Gotu kola extract,Centella asiatica

Snow oxalic acid

Asiatic acid-RM

Asiatic Acid, 95%

Centellaasiatica(L.)Urb.

464-92-6

C30H48O5

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Antineoplastic

Steroids

The group of Asiaticoside

Pentacyclic Triterpenes

C13 to C42+

Carbonyl Compounds

Carboxylic Acids

464-92-6

API