Aceglatone

Product Name: Aceglatone
CAS No.: 642-83-1
Chemical Name: Aceglatone
Synonyms: Glucaron;Aceglatone;Aceglatone USP/EP/BP;Glucaro-(1→4:6→3)-dilactone diacetate;Furo[3,2-b]furan, D-glucaric acid deriv.;D-Glucaric acid, di-γ-lactone, 2,5-diacetate;2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone;O2,O5-diacetylglucaric acid 1,4:6,3-dilactone;Glucaric acid, di-γ-lactone, diacetate, D- (8CI);Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI)
CBNumber: CB51177953
Molecular Formula: C10H10O8
Formula Weight: 258.18
MOL File: 642-83-1.mol

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Aceglatone Property

Melting point:: 185-186° (Hirasaka)
Density: 1.49

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Hazard and Precautionary Statements (GHS)

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Aceglatone Chemical Properties,Usage,Production

Uses

Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1].

Definition

ChEBI: Aceglatone is an organic molecular entity.

References

[1] Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats DOI:10.3892/mmr_00000022

Aceglatone Preparation Products And Raw materials

Raw materials

Preparation Products

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Aceglatone Suppliers

China 8 United States 4 Global 12

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
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Alfa Chemistry

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Email: info@Alfa-Chemistry.com
Country: United States
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642-83-1, AceglatoneRelated Search:

Aceglatone 2-Hydroxyhexanedial (S)-(-)-alpha-Hydroxy-gamma-butyrolactone Isosorbide ETHYL (S)-(-)-2-METHOXYPROPIONATE D-Glucurone Isosorbide-2-Acetate (S)-(-)-2-ACETOXYPROPIONIC ACID 2-(oxolan-2-yl)acetic acid 4-Iodophenol Isosorbide dimethyl ether (S)-5-Hydroxymethyldihydrofuran-2-one D-LYXONO-1,4-LACTONE L-ERYTHRONO-1,4-LACTONE ETHYL 2-ETHOXYPROPIONATE (R)-3-ACETOXY-GAMMA-BUTYROLACTONE D-XYLONO-1,4-LACTONE L-Threonolactone

Aceglatone

(2-acetyloxy-3,7-dioxo-4,8-dioxabicyclo[3.3.0]oct-6-yl) acetate

2-O,5-O-Diacetyl-D-glucaric acid 1,4:6,3-dilactone

2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone

2,5-di-O-Acetyl-D-glucosaccharo-(1→4:6→3)-dilactone

D-Glucaric acid, di-γ-lactone, 2,5-diacetate

Furo[3,2-b]furan, D-glucaric acid deriv.

Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI)

Glucaric acid, di-γ-lactone, diacetate, D- (8CI)

Glucaro-(1→4:6→3)-dilactone diacetate

Glucaron

O2,O5-diacetylglucaric acid 1,4:6,3-dilactone

Aceglatone USP/EP/BP

642-83-1

C10H10O8