ChemicalBook > CAS DataBase List > 2-Hydroxy-5-pyridinecarboxylic acid

2-Hydroxy-5-pyridinecarboxylic acid

Product Name
2-Hydroxy-5-pyridinecarboxylic acid
CAS No.
5006-66-6
Chemical Name
2-Hydroxy-5-pyridinecarboxylic acid
Synonyms
6-HYDROXYNICOTINIC ACID;6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;NSC 8620;PD022551;PD-22551;NSC 35054;NSC 53377;NSC 654077;6-Hydroxyniacin
CBNumber
CB5119727
Molecular Formula
C6H5NO3
Formula Weight
139.11
MOL File
5006-66-6.mol
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2-Hydroxy-5-pyridinecarboxylic acid Property

Melting point:
>300 °C (lit.)
Boiling point:
255.04°C (rough estimate)
Density 
1.4429 (rough estimate)
refractive index 
1.5423 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Powder
pka
3.80±0.50(Predicted)
color 
Off-white to light brown
BRN 
472182
InChI
InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChIKey
BLHCMGRVFXRYRN-UHFFFAOYSA-N
SMILES
C1NC(=O)C=CC=1C(O)=O
CAS DataBase Reference
5006-66-6(CAS DataBase Reference)
EPA Substance Registry System
6-Hydroxynicotinic acid (5006-66-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2470
Product name
6-Hydroxynicotinic acid
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
128759
Product name
6-Hydroxypyridine-3-carboxylic acid
Purity
98%
Packaging
25g
Price
$86.4
Updated
2024/03/01
Sigma-Aldrich
Product number
128759
Product name
6-Hydroxypyridine-3-carboxylic acid
Purity
98%
Packaging
100g
Price
$220
Updated
2024/03/01
TCI Chemical
Product number
H0633
Product name
6-Hydroxynicotinic Acid
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$411
Updated
2024/03/01
TCI Chemical
Product number
H0633
Product name
6-Hydroxynicotinic Acid
Purity
>97.0%(GC)(T)
Packaging
250g
Price
$1877
Updated
2023/06/20
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2-Hydroxy-5-pyridinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

Nicotinic Acid derivative, found in fruit hypanthium.

Uses

Metabolite of nicotinamide. Stimulates adrenocortical secretion

Uses

6-Hydroxynicotinic acid is used as building block in chemical synthesis.

Definition

ChEBI: A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.

General Description

6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) reacts with Ln(2)O(3) (Ln = Nd, Sm, Eu, Gd) and oxalic acid (H(2)OX) to generate four novel lanthanide-organic coordination polymeric networks.

Purification Methods

It crystallises from water with m 303.4-303.7o(dec), or with m 325o(dec) from aqueous EtOH. The methyl ester crystallises from Me2CO with m 166o and pK2 0 9.92. [Albert J Chem Soc 1020 1960, Beilstein 22 III/IV 2147, 22/6 V 119.]

2-Hydroxy-5-pyridinecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-6-chloronicotinic acid 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 2-HYDROXY-3,5-DINITROPYRIDINE 5-BROMO-6-HYDROXYNICOTINIC ACID
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View Lastest Price from 2-Hydroxy-5-pyridinecarboxylic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Hebei Yanxi Chemical Co., Ltd.
Product
2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-13
Firsky International Trade (Wuhan) Co., Ltd
Product
6-Hydroxynicotinic acid 5006-66-6
Price
US $30.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2023-10-08

5006-66-6, 2-Hydroxy-5-pyridinecarboxylic acidRelated Search:

5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID Nicotinic acid 6-Chloronicotinic acid 6-HYDROXYNICOTINONITRILE Ethyl 2-aminopyridine-3-carboxylate 3-Nitropyridine NICOTINIC-D4 ACID Isonicotinic acid 2-Aminopyridine N-oxide 3,5-DINITROPYRIDINE 2-BROMOPYRIDINE N-OXIDE 2,5-PYRIDINEDICARBOXYLIC ACID 3-Ethylpyridine 5-Ethyl-2-methylpyridine 2,2'-Bipyridine-5,5'-dicarboxylic acid 5-NITRONICOTINIC ACID 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo- (9CI) 2-Hydroxy-5-pyridinecarboxylic acid

  • TIMTEC-BB SBB004181
  • 1,6-dihydro-6-oxo-3-pyridinecarboxylicaci
  • SPECS AI-942/25034174
  • 2-HYDROXY-5-PYRIDINECARBOXYLIC ACID
  • 2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID
  • 5-CARBOXY-2(1H)-PYRIDINONE
  • 6-HYDROXY-3-PYRIDINECARBOXYLIC ACID
  • 6-HYDROXYNICOTINIC ACID
  • 6-HYDROXYPYRIDIN-3-CARBOXYLIC ACID
  • 6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID
  • 3-PYRIDINECARBOXYLIC ACID, 1,6-DIHYDRO-6-OXO
  • 6-oxonicotinic acid
  • 6-Hydroxynicotinic acid , 2-Hydroxy-5-pyridinecarboxylic acid
  • 2-Hydroxy-5-pyridinecarboxylic acid, 6-Hydroxynicotinic acid
  • 6-Hydroxyniacin
  • 2-Pyridone-5-carboxylic acid
  • 5-Carboxy-2-pyridone
  • 6-Hydroxynicotinic acid ,99%
  • 1,6-Dihydro-6-oxopyridine-3-carboxylic acid
  • 2-Hydroxy-5-pyridinecarboxlic acid
  • 6-Hydroxynicotinic
  • 1,6-dihydro-6-oxo-3-pyridinecarboxylic acid
  • 6-Hydroxynicotinic acid 98%
  • 6-Oxo-1, 6-dihydro-pyridine-3-carboxylic acid
  • 2-HydroxypyridineCarboxylicAcid
  • 6-Hydroxynicotinic acid, 98+%
  • 6-oxo-1H-pyridine-3-carboxylic acid
  • 5-HYDROXYNICOTINIC ACID 5-HYDROXYNICOTINIC ACID
  • 6-HYDROXYPYRIDINNICOTINIC ACID 6-HYDROXYPYRIDIN-3-CARBOXYLIC ACID
  • HydroxynicotinicAci
  • 6-Hydroxypyridine-3-carboxylic acid 98%
  • 6-Hydroxynicotinic acid, 98.5%
  • 1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid for synthesis
  • 2-Hydroxy-5-pyridine
  • Nicotinic acid-6-hydroxy
  • 6-Hydroxynicotinic Acid (50 mg)
  • 2-pyridone-5-carbonacid
  • 6-Hydroxynicotinic acid, 99% 25GR
  • 1,6-Dihydro-6-oxo-nicotinic Acid
  • 2-Hydroxy-5-carboxypyridine
  • NSC 35054
  • NSC 53377
  • NSC 8620
  • 6-HydroxynicotinicAcid&gt
  • 6-Hydroxypyridine-3-carboxylic acid@100 μg/mL in Methanol
  • 6-Hydroxypyridine-3-carboxyL
  • Nicotinic Acid Impurity 13（6-Hydroxy Nicotinic Acid）
  • 2-Hydroxy-5-pyridinecarboxylic acid ISO 9001：2015 REACH
  • 6-Hydroxynicotinic Acid (1327408)
  • DIBA (Antineoplastic)
  • NSC 654077
  • PD022551
  • PD-22551
  • Avatrombopag Impurity 68
  • 6-Hydroxynicotinic Acid, ≥ 97.0%
  • 5006-66-6
  • 50066-66-6
  • CARBOXYLIC ACID