ChemicalBook > CAS DataBase List > 2-Hydroxy-5-pyridinecarboxylic acid

2-Hydroxy-5-pyridinecarboxylic acid

Product Name: 2-Hydroxy-5-pyridinecarboxylic acid
CAS No.: 5006-66-6
Chemical Name: 2-Hydroxy-5-pyridinecarboxylic acid
Synonyms: 6-HYDROXYNICOTINIC ACID;6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;NSC 8620;PD022551;PD-22551;NSC 35054;NSC 53377;NSC 654077;6-Hydroxyniacin
CBNumber: CB5119727
Molecular Formula: C6H5NO3
Formula Weight: 139.11
MOL File: 5006-66-6.mol

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2-Hydroxy-5-pyridinecarboxylic acid Property

Melting point:: >300 °C (lit.)
Boiling point:: 255.04°C (rough estimate)
Density: 1.4429 (rough estimate)
refractive index: 1.5423 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Powder
pka: 3.80±0.50(Predicted)
color: Off-white to light brown
BRN: 472182
InChI: InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChIKey: BLHCMGRVFXRYRN-UHFFFAOYSA-N
SMILES: C1NC(=O)C=CC=1C(O)=O
CAS DataBase Reference: 5006-66-6(CAS DataBase Reference)
EPA Substance Registry System: 6-Hydroxynicotinic acid (5006-66-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2470
Product name: 6-Hydroxynicotinic acid
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 100MG
Price: $545.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 128759
Product name: 6-Hydroxypyridine-3-carboxylic acid
Purity: 98%
Packaging: 25g
Price: $89.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 128759
Product name: 6-Hydroxypyridine-3-carboxylic acid
Purity: 98%
Packaging: 100g
Price: $227
Updated: 2025/07/31

TCI Chemical

Product number: H0633
Product name: 6-Hydroxynicotinic Acid
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $406
Updated: 2025/07/31

TCI Chemical

Product number: H0633
Product name: 6-Hydroxynicotinic Acid
Purity: >97.0%(GC)(T)
Packaging: 250g
Price: $1877
Updated: 2023/06/20

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2-Hydroxy-5-pyridinecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

Nicotinic Acid derivative, found in fruit hypanthium.

Uses

Metabolite of nicotinamide. Stimulates adrenocortical secretion

Uses

6-Hydroxynicotinic acid is used as building block in chemical synthesis.

Definition

ChEBI: A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.

General Description

6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) reacts with Ln(2)O(3) (Ln = Nd, Sm, Eu, Gd) and oxalic acid (H(2)OX) to generate four novel lanthanide-organic coordination polymeric networks.

Purification Methods

It crystallises from water with m 303.4-303.7o(dec), or with m 325o(dec) from aqueous EtOH. The methyl ester crystallises from Me2CO with m 166o and pK2 0 9.92. [Albert J Chem Soc 1020 1960, Beilstein 22 III/IV 2147, 22/6 V 119.]

2-Hydroxy-5-pyridinecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-6-chloronicotinic acid 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 2-HYDROXY-3,5-DINITROPYRIDINE 5-BROMO-6-HYDROXYNICOTINIC ACID

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View Lastest Price from 2-Hydroxy-5-pyridinecarboxylic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Hebei Yanxi Chemical Co., Ltd.

Product: 2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-13

5006-66-6, 2-Hydroxy-5-pyridinecarboxylic acidRelated Search:

5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID Nicotinic acid 6-Chloronicotinic acid 6-HYDROXYNICOTINONITRILE Ethyl 2-aminopyridine-3-carboxylate 3-Nitropyridine NICOTINIC-D4 ACID Isonicotinic acid 2-Aminopyridine N-oxide 3,5-DINITROPYRIDINE 2-BROMOPYRIDINE N-OXIDE 2,5-PYRIDINEDICARBOXYLIC ACID 3-Ethylpyridine 5-Ethyl-2-methylpyridine 2,2'-Bipyridine-5,5'-dicarboxylic acid 5-NITRONICOTINIC ACID 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo- (9CI) 2-Hydroxy-5-pyridinecarboxylic acid

TIMTEC-BB SBB004181

1,6-dihydro-6-oxo-3-pyridinecarboxylicaci

SPECS AI-942/25034174

2-HYDROXY-5-PYRIDINECARBOXYLIC ACID

2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID

5-CARBOXY-2(1H)-PYRIDINONE

6-HYDROXY-3-PYRIDINECARBOXYLIC ACID

6-HYDROXYNICOTINIC ACID

6-HYDROXYPYRIDIN-3-CARBOXYLIC ACID

6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID

3-PYRIDINECARBOXYLIC ACID, 1,6-DIHYDRO-6-OXO

6-oxonicotinic acid

6-Hydroxynicotinic acid , 2-Hydroxy-5-pyridinecarboxylic acid

2-Hydroxy-5-pyridinecarboxylic acid, 6-Hydroxynicotinic acid

6-Hydroxyniacin

2-Pyridone-5-carboxylic acid

5-Carboxy-2-pyridone

6-Hydroxynicotinic acid ,99%

1,6-Dihydro-6-oxopyridine-3-carboxylic acid

2-Hydroxy-5-pyridinecarboxlic acid

6-Hydroxynicotinic

1,6-dihydro-6-oxo-3-pyridinecarboxylic acid

6-Hydroxynicotinic acid 98%

6-Oxo-1, 6-dihydro-pyridine-3-carboxylic acid

2-HydroxypyridineCarboxylicAcid

6-Hydroxynicotinic acid, 98+%

6-oxo-1H-pyridine-3-carboxylic acid

5-HYDROXYNICOTINIC ACID 5-HYDROXYNICOTINIC ACID

6-HYDROXYPYRIDINNICOTINIC ACID 6-HYDROXYPYRIDIN-3-CARBOXYLIC ACID

HydroxynicotinicAci

6-Hydroxypyridine-3-carboxylic acid 98%

6-Hydroxynicotinic acid, 98.5%

1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid for synthesis

2-Hydroxy-5-pyridine

Nicotinic acid-6-hydroxy

6-Hydroxynicotinic Acid (50 mg)

2-pyridone-5-carbonacid

6-Hydroxynicotinic acid, 99% 25GR

1,6-Dihydro-6-oxo-nicotinic Acid

2-Hydroxy-5-carboxypyridine

NSC 35054

NSC 53377

NSC 8620

6-HydroxynicotinicAcid&gt

6-Hydroxypyridine-3-carboxylic acid@100 μg/mL in Methanol

6-Hydroxypyridine-3-carboxyL

Nicotinic Acid Impurity 13（6-Hydroxy Nicotinic Acid）

2-Hydroxy-5-pyridinecarboxylic acid ISO 9001：2015 REACH

6-Hydroxynicotinic Acid (1327408)

DIBA (Antineoplastic)

NSC 654077

PD022551

PD-22551

Avatrombopag Impurity 68

6-Hydroxynicotinic Acid, ≥ 97.0%

6-Hydroxynicotinic acid, 10 mM in DMSO

5-hydroxypyridine-4-carboxylic acid

6-hydroxynicotinicaci