6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER
Uses- Product Name
- 6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER
- CAS No.
- 26256-72-4
- Chemical Name
- 6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER
- Synonyms
- Methyl 6-methoxy;Methyl 6-methoxypicolinate;methyl 6-methoxy-2-pyridinecarboxylate;6-Methoxypyridinecarboxylic acid methyl ester;6-Methoxy-2-Pyridinecarboxylic Acid Methyl Ester;2-Pyridinecarboxylic acid, 6-Methoxy-, Methyl ester;Methyl 6-
methoxypyridine- 2- carboxylate - CBNumber
- CB51229335
- Molecular Formula
- C8H9NO3
- Formula Weight
- 167.16
- MOL File
- 26256-72-4.mol
6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER Property
- Melting point:
- 33-38℃
- Boiling point:
- 256.6±20.0 °C(Predicted)
- Density
- 1.156±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 0.41±0.10(Predicted)
- color
- White
- InChI
- InChI=1S/C8H9NO3/c1-11-7-5-3-4-6(9-7)8(10)12-2/h3-5H,1-2H3
- InChIKey
- QCCJUEURAZMEGY-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)=NC(OC)=CC=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M338445
- Product name
- Methyl6-Methoxypicolinate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- Z0452
- Product name
- Methyl 6-methoxypyridine-2-carboxylate
- Packaging
- 1g
- Price
- $53
- Updated
- 2021/12/16
- Product number
- Z0452
- Product name
- Methyl 6-methoxypyridine-2-carboxylate
- Packaging
- 5g
- Price
- $147
- Updated
- 2021/12/16
- Product number
- A178187
- Product name
- Methyl6-methoxypicolinate
- Purity
- 98%
- Packaging
- 100mg
- Price
- $9
- Updated
- 2021/12/16
- Product number
- A178187
- Product name
- Methyl6-methoxypicolinate
- Purity
- 98%
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER Chemical Properties,Usage,Production
Uses
Methyl 6-methoxy-2-pyridinecarboxylate is a useful research chemical.
Synthesis Reference(s)
Tetrahedron Letters, 15, p. 4339, 1974 DOI: 10.1016/S0040-4039(01)92158-6
Synthesis
19621-92-2
74-88-4
26256-72-4
General procedure for the synthesis of methyl 6-methoxypyridine-2-carboxylate from 6-hydroxypyridine-2-carboxylic acid and iodomethane: 6-hydroxypyridine-2-carboxylic acid (1 g, 7.19 mmol) and silver carbonate (2.2 g, 7.90 mmol) were placed in a round-bottomed flask, and chloroform (20 mL) was added to dissolve. Subsequently, iodomethane (1 mL, 15.81 mmol) was added slowly and dropwise. The reaction mixture was stirred at 60°C for 26 hours. After completion of the reaction, the mixture was filtered and extracted with chloroform. Next, the extract was vacuum filtered and vacuum distilled to remove the solvent. Finally, the residue was purified by column chromatography (eluent ratio of ethyl acetate: hexane = 1:5) to afford the target product methyl 6-methoxypyridine-2-carboxylate (1.25 g, 100% yield).
References
[1] Patent: WO2014/3483, 2014, A1. Location in patent: Page/Page column 34
[2] Organic and Biomolecular Chemistry, 2006, vol. 4, # 6, p. 1071 - 1084
[3] Organic Letters, 2009, vol. 11, # 23, p. 5562 - 5565
[4] Patent: WO2011/79076, 2011, A1. Location in patent: Page/Page column 93
6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER Preparation Products And Raw materials
Raw materials
Preparation Products
6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER Suppliers
- Tel
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- sales@ajchem.in
- Country
- India
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View Lastest Price from 6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER manufacturers
- Product
- 6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER 26256-72-4
- Price
- US $100.00-600.00/g
- Min. Order
- 5g
- Purity
- 99%
- Supply Ability
- 50
- Release date
- 2024-07-11
- Product
- 6-METHOXY-PYRIDINE-2-CARBOXYLICACIDMETHYLESTER 26256-72-4
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-10