Oxetan-3-ol

Product Name: Oxetan-3-ol
CAS No.: 7748-36-9
Chemical Name: Oxetan-3-ol
Synonyms: 3-HYDROXYOXETANE;3-Oxetanol;Ooetan-3-ol;Oxetan-3-ol;3-Oxetanol>3-Oxocyclobutanol;Oxetan-3-ol, >=97%;1,3-Epoxy-2-propanol;3-Hydroxyoxetane 95%;3-Oxetanol - [O5686]
CBNumber: CB51235204
Molecular Formula: C3H6O2
Formula Weight: 74.08
MOL File: 7748-36-9.mol

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Oxetan-3-ol Property

Boiling point:: 153℃
Density: 1.167
refractive index: 1.438
Flash point:: 87°(189°F)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform (Soluble), Methanol (Slightly)
pka: 13.68±0.20(Predicted)
form: Liquid
color: Clear colorless
InChI: InChI=1S/C3H6O2/c4-3-1-5-2-3/h3-4H,1-2H2
InChIKey: QMLWSAXEQSBAAQ-UHFFFAOYSA-N
SMILES: O1CC(O)C1

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
RIDADR: NA 1993 / PGIII
WGK Germany: 3
TSCA: No
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 733296
Product name: 3-Hydroxyoxetane
Purity: 95%
Packaging: 1g
Price: $28.1
Updated: 2025/07/31

TCI Chemical

Product number: O0409
Product name: 3-Oxetanol
Purity: >96.0%(GC)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: O0409
Product name: 3-Oxetanol
Purity: >96.0%(GC)
Packaging: 5g
Price: $78
Updated: 2025/07/31

TRC

Product number: O846575
Product name: 3-Oxetanol
Packaging: 1g
Price: $55
Updated: 2021/12/16

TRC

Product number: O846575
Product name: 3-Oxetanol
Packaging: 25g
Price: $275
Updated: 2021/12/16

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Oxetan-3-ol Chemical Properties,Usage,Production

Chemical Properties

Colorless Transparent Liquid

Uses

3-Oxetanol is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.

Synthesis

95257-22-0

7748-36-9

General procedure for the synthesis of oxetan-3-ol from 3-(phenylmethoxy)oxetane: 3-(phenylmethoxy)oxetane (59 g, 0.41 mol) and 10% palladium/carbon catalyst were added to methanol (1000 mL) in an autoclave. The hydrogenation reaction was completed by reacting under hydrogen atmosphere (10 atm) at 40°C for 24 hours. Upon completion of the reaction, the palladium/carbon catalyst was removed by filtration, followed by concentration under reduced pressure to remove the solvent. The colorless liquid product oxetan-3-ol (142.63 g) was obtained by distillation in 95.84% yield.

References

[1] Patent: CN103554064, 2016, B. Location in patent: Paragraph 0031; 0032; 0041; 0042

Oxetan-3-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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Oxetan-3-ol Suppliers

Americas 1 Belgium 1 China 288 Europe 1 Germany 3 India 11 Japan 1 The Netherlands 1 United Kingdom 3 United States 26 Global 336

Zhenjiang D&A Biological Technology Co., Ltd.

Tel: 18912101619
Email: wxf2005a@126.com
Country: China
ProdList: 94
Advantage: 58

NanJing FineTech Chemical Co., Ltd

Tel: 025-52078417 17701591256
Email: sales@fine-chemtech.com
Country: China
ProdList: 288
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Jinan Shuhong Biotechnology Co., Ltd.

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Email: 6348314@qq.com
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

ChemFuture PharmaTech (Jiangsu) Ltd

Tel: 5108538618
Fax: 86 510 85386988-8017
Email: suger.wang@chemfuture.com
Country: China
ProdList: 832
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
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ProdList: 24529
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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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View Lastest Price from Oxetan-3-ol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Oxetan-3-ol 7748-36-9
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Hebei Yanxi Chemical Co., Ltd.

Product: Oxetan-3-ol 7748-36-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-28

Shaanxi Dideu Medichem Co. Ltd

Product: Oxetan-3-ol 7748-36-9
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

7748-36-9, Oxetan-3-olRelated Search:

3-Methyl butynol Ketorolac tromethamine Fosfomycin tromethamine 3-Oxetanemethanol oxetane-3-carbaldehyde methyl oxetane-3-carboxylate ethyl 2-(oxetan-3-ylidene)acetate 4,4,5,5-TetraMethyl-2-(oxetan-3-yl)-1,3,2-dioxaborolane oxetan-3-ylmethanol Hydrogenated Cottonseed Oil oxetan-3-yl-acetic acid ethyl ester Ethyl oxetane-3-carboxylate 3-Oxetanethiol 3-OXETANECARBOXYLIC ACID 2-aminomethyloxetane TOLUENE-4-SULFONIC ACID OXETAN-2-YLMETHYL ESTER Oxetan-3-ylmethyl 4-methylbenzenesulfonate Benzyl oxetan-3-ylcarbamate

3-Oxetanol

Ooetan-3-ol

Oxetan-3-ol, 1,3-Epoxypropan-2-ol

3-Hydroxyoxetane 95%

3 - hydroxyl oxygen heterocyclic butane

1,3-Epoxy-2-propanol

Oxetan-3-ol, >=97%

Oxetan-3-ol

3-HYDROXYOXETANE

3-Oxetanol&gt

3-Oxetanol (9CI, ACI)

3-Oxocyclobutanol

3-Oxetanol - [O5686]

7748-36-9

748-36-9

API intermediates

Alcohols and Derivatives

Heterocycles

Building Blocks/Intermediates

Pyridines

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