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5-Nitrosalicylic acid

Product Name
5-Nitrosalicylic acid
CAS No.
96-97-9
Chemical Name
5-Nitrosalicylic acid
Synonyms
5-NitrosaL;JACS-96-97-9;ANILOTIC ACID;AURORA KA-2534;TIMTEC-BB SBB006535;RARECHEM AL BE 0192;5-NITROSALICYLIC ACID;Mesalazine Impurity N;Mesalamine impurity N;Mesalazine Impurity 21
CBNumber
CB5133842
Molecular Formula
C7H5NO5
Formula Weight
183.12
MOL File
96-97-9.mol
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5-Nitrosalicylic acid Property

Melting point:
228-230 °C(lit.)
Boiling point:
316.77°C (rough estimate)
Density 
1,65 g/cm3
vapor pressure 
0Pa at 25℃
refractive index 
1.6280 (estimate)
storage temp. 
no restrictions.
solubility 
water: soluble1g in 1475ml(lit.)
form 
Liquid
pka
pK1:2.12 (25°C)
color 
Clear yellow-beige to orange-brown
Water Solubility 
Soluble in water 1g/1475ml .
Merck 
14,6631
BRN 
2213719
InChIKey
PPDRLQLKHRZIJC-UHFFFAOYSA-N
LogP
1.158 at 25℃
CAS DataBase Reference
96-97-9(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 2-hydroxy-5-nitro- (96-97-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29182990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
247871
Product name
2-Hydroxy-5-nitrobenzoic acid
Purity
99%
Packaging
25g
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
N0257
Product name
5-Nitrosalicylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$52
Updated
2024/03/01
TCI Chemical
Product number
N0257
Product name
5-Nitrosalicylic Acid
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$350
Updated
2024/03/01
Alfa Aesar
Product number
A13010
Product name
5-Nitrosalicylic acid, 98%
Packaging
5g
Price
$24.65
Updated
2024/03/01
Alfa Aesar
Product number
A13010
Product name
5-Nitrosalicylic acid, 98%
Packaging
25g
Price
$63.65
Updated
2024/03/01
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5-Nitrosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Uses

5-Nitrosalicylic Acid is a salicylic acid derivative with anti-inflammatory effect against colitis.

Definition

ChEBI: A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 2377, 1995 DOI: 10.1016/0040-4039(95)00281-G

General Description

2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the acid from Me2CO (charcoal), then twice more from Me2CO alone, aqueous EtOH (m 234-236o) or H2O (m 232-233o). [Beilstein 10 III 197, 10 IV 255.]

5-Nitrosalicylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

5-Aminosalicylic acid
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5-Nitrosalicylic acid Suppliers

Americas 1 Austria 1 Belgium 3 Canada 1 China 254 Czech Republic 1 Europe 3 France 1 Germany 12 India 57 Japan 4 Poland 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 19 United States 45 Global 410
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
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Germany
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66
Connect Chemicals GmbH
Tel
+49 2102 2077 19
Fax
+49 2102 2077 40
Email
Martin.Klapper@connectchemicals.com
Country
Germany
ProdList
404
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62
Alfa Aesar, Thermo Fisher Scientific
Tel
--
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Email
es@alfa.com
Country
Germany
ProdList
5123
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58
HPC Standards GmbH
Tel
--
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Email
chulze@hpc-standards.com
Country
Germany
ProdList
2139
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Merck Millipore
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Email
ccc@merckgroup.com
Country
Germany
ProdList
2008
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CHEMOS GmbH & Co. KG
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Email
chemos@chemos.de
Country
Germany
ProdList
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Aaron Chemistry GmbH
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sales@aaron-chemistry.de
Country
Germany
ProdList
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ABCR GmbH & CO. KG
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info@abcr.de
Country
Germany
ProdList
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Service Chemical Inc.
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sales@chemos-group.com
Country
Germany
ProdList
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Rare Chemicals GmbH
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sales@rarechem.de
Country
Germany
ProdList
6297
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Merck Schuchardt OHG
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Email
schuchardt-vertrieb@merck.de
Country
Germany
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EMKA-Chemie Organische Feinchemikalien
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View Lastest Price from 5-Nitrosalicylic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
5-Nitrosalicylic acid 96-97-9
Price
US $58.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Nitrosalicylic Acid 96-97-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.3%
Supply Ability
200kg
Release date
2024-05-14
Hebei Yanxi Chemical Co., Ltd.
Product
5-Nitrosalicylic acid 96-97-9
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-10-20

96-97-9, 5-Nitrosalicylic acidRelated Search:

3,5-Dihydroxybenzoic acid Sodium 3-nitrobenzoate 2,3,4-Trihydroxybenzoic acid 4-Nitrophenyl chloroformate 4-Methylsalicylic acid Citric acid Acetylsalicylic acid 4-Nitrobenzoic acid 4-Hydroxybenzoic acid CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate 3-NITROSALICYLIC ACID 98+%,3-NITROSALICYLIC ACID Salicylic acid Glycine Folic acid 2-Chloro-5-nitrobenzoic acid 2-Chlorobenzoic acid Ascoric Acid

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  • RARECHEM AL BE 0192
  • TIMTEC-BB SBB006535
  • 5-NITROSALICYLIC ACID
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  • 5-Nitrosalicylicacid,98%
  • Benzoic acid, 2-hydroxy-5-nitro-
  • 2-Hydroxy-3-nitrobenzoic acid 98%
  • 2-HYDROXY-5-NITROBENZOIC ACID / 5-NITROSALICYLIC ACID
  • 5-NITROSALICYLIC ACID 99%
  • 5-Nitro-o-hydroxybenzoic acid
  • 5-Nitrosalicylic acid,99%
  • 5-Nitrosalicylic Acid (5-NSA)
  • 5-Nitrosalicylic acid, 99% 25GR
  • 5-Nitrosalicylic acid, 99% 5GR
  • Mesalamine Impurity N (5-Nitrosalicylic Acid)
  • Mesalazine Impurity 21(Mesalazine EP Impurity N)
  • Mesalazine EP IMpurity N
  • JACS-96-97-9
  • 2-Hydroxy-5-nitrobenzoic Acid (5-Ni
  • 5-NitrosalicylicAcid&gt
  • Salicylic acid, 5-nitro-
  • 2-HYDROXY-5-NITROBENZOIC ACID FOR SYNTHE
  • 5-NitrosaL
  • Mesalazine Impurity 21
  • 5-Nitrosalicylic acid 96-97-9
  • 2-hydroxy-5-nitrobenzoic acid(96-97-9)
  • Mesalazine Impurity N
  • Mesalamine impurity N
  • Mesalamine EP Impurity N
  • Mesalazine EP Impurity N 2-hydroxy-5-nitrobenzoic acid (5-nitrosalicylic acid).
  • 5-Nitrosalicylic Acid, ≥ 98.0%
  • 2-Hydroxy, 5-Nitro Benzoic Acid (Mnesalamine imp-N)
  • 5-Nittro salicylic acid
  • 96-97-9
  • 96-97-5
  • C7H5O5N
  • Organic Building Blocks
  • CARBOXYLIC ACID
  • Building Blocks
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • C7
  • Carbonyl Compounds
  • Organic acids
  • API intermediates
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • FINE Chemical & INTERMEDIATES