5-Nitrosalicylic acid

Product Name: 5-Nitrosalicylic acid
CAS No.: 96-97-9
Chemical Name: 5-Nitrosalicylic acid
Synonyms: 5-NitrosaL;JACS-96-97-9;ANILOTIC ACID;AURORA KA-2534;TIMTEC-BB SBB006535;RARECHEM AL BE 0192;5-NITROSALICYLIC ACID;Mesalazine Impurity N;Mesalamine impurity N;Mesalazine Impurity 21
CBNumber: CB5133842
Molecular Formula: C7H5NO5
Formula Weight: 183.12
MOL File: 96-97-9.mol

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5-Nitrosalicylic acid Property

Melting point:: 228-230 °C(lit.)
Boiling point:: 316.77°C (rough estimate)
Density: 1,65 g/cm³
vapor pressure: 0Pa at 25℃
refractive index: 1.6280 (estimate)
storage temp.: no restrictions.
solubility: water: soluble1g in 1475ml(lit.)
form: Liquid
pka: pK1:2.12 (25°C)
color: Clear yellow-beige to orange-brown
Water Solubility: Soluble in water 1g/1475ml .
Merck: 14,6631
BRN: 2213719
InChIKey: PPDRLQLKHRZIJC-UHFFFAOYSA-N
LogP: 1.158 at 25℃
CAS DataBase Reference: 96-97-9(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 2-hydroxy-5-nitro- (96-97-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
Hazard Note: Irritant
TSCA: Yes
HS Code: 29182990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 247871
Product name: 2-Hydroxy-5-nitrobenzoic acid
Purity: 99%
Packaging: 25g
Price: $113
Updated: 2024/03/01

TCI Chemical

Product number: N0257
Product name: 5-Nitrosalicylic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $52
Updated: 2024/03/01

TCI Chemical

Product number: N0257
Product name: 5-Nitrosalicylic Acid
Purity: >98.0%(GC)(T)
Packaging: 250g
Price: $350
Updated: 2024/03/01

Alfa Aesar

Product number: A13010
Product name: 5-Nitrosalicylic acid, 98%
Packaging: 5g
Price: $24.65
Updated: 2024/03/01

Alfa Aesar

Product number: A13010
Product name: 5-Nitrosalicylic acid, 98%
Packaging: 25g
Price: $63.65
Updated: 2024/03/01

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5-Nitrosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Uses

5-Nitrosalicylic Acid is a salicylic acid derivative with anti-inflammatory effect against colitis.

Definition

ChEBI: A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 2377, 1995 DOI: 10.1016/0040-4039(95)00281-G

General Description

2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low M_rprotein tyrosine phosphatase. The inhibition constant has been evaluated.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the acid from Me2CO (charcoal), then twice more from Me2CO alone, aqueous EtOH (m 234-236o) or H2O (m 232-233o). [Beilstein 10 III 197, 10 IV 255.]

5-Nitrosalicylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

5-Aminosalicylic acid

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5-Nitrosalicylic acid Suppliers

Americas 1 Austria 1 Belgium 3 Canada 1 China 254 Czech Republic 1 Europe 3 France 1 Germany 12 India 57 Japan 4 Poland 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 19 United States 45 Global 410

Ningbo jinuo chemical co., LTD

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Weifang Boteng Chemical Co.,Ltd

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Henan Vcommend Consultrading Co., Ltd.

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J & K SCIENTIFIC LTD.

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INTATRADE GmbH

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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
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ProdList: 24529
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View Lastest Price from 5-Nitrosalicylic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 5-Nitrosalicylic acid 96-97-9
Price: US $58.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-22

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Nitrosalicylic Acid 96-97-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.3%
Supply Ability: 200kg
Release date: 2024-05-14

Hebei Yanxi Chemical Co., Ltd.

Product: 5-Nitrosalicylic acid 96-97-9
Price: US $40.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-20

96-97-9, 5-Nitrosalicylic acidRelated Search:

3,5-Dihydroxybenzoic acid Sodium 3-nitrobenzoate 2,3,4-Trihydroxybenzoic acid 4-Nitrophenyl chloroformate 4-Methylsalicylic acid Citric acid Acetylsalicylic acid 4-Nitrobenzoic acid 4-Hydroxybenzoic acid CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate 3-NITROSALICYLIC ACID 98+%,3-NITROSALICYLIC ACID Salicylic acid Glycine Folic acid 2-Chloro-5-nitrobenzoic acid 2-Chlorobenzoic acid Ascoric Acid

2-hydroxy-5-nitro-benzoicaci

AURORA KA-2534

ANILOTIC ACID

2-HYDROXY-5-NITROBENZOIC ACID

RARECHEM AL BE 0192

TIMTEC-BB SBB006535

5-NITROSALICYLIC ACID

5-NITRO-2-HYDROXY-BENZOIC ACID

5-Nitrosalicylicacid,98%

Benzoic acid, 2-hydroxy-5-nitro-

2-Hydroxy-3-nitrobenzoic acid 98%

2-HYDROXY-5-NITROBENZOIC ACID / 5-NITROSALICYLIC ACID

5-NITROSALICYLIC ACID 99%

5-Nitro-o-hydroxybenzoic acid

5-Nitrosalicylic acid,99%

5-Nitrosalicylic Acid (5-NSA)

5-Nitrosalicylic acid, 99% 25GR

5-Nitrosalicylic acid, 99% 5GR

Mesalamine Impurity N (5-Nitrosalicylic Acid)

Mesalazine Impurity 21(Mesalazine EP Impurity N)

Mesalazine EP IMpurity N

JACS-96-97-9

2-Hydroxy-5-nitrobenzoic Acid (5-Ni

5-NitrosalicylicAcid&gt

Salicylic acid, 5-nitro-

2-HYDROXY-5-NITROBENZOIC ACID FOR SYNTHE

5-NitrosaL

Mesalazine Impurity 21

5-Nitrosalicylic acid 96-97-9

2-hydroxy-5-nitrobenzoic acid(96-97-9)

Mesalazine Impurity N

Mesalamine impurity N

Mesalamine EP Impurity N

Mesalazine EP Impurity N 2-hydroxy-5-nitrobenzoic acid (5-nitrosalicylic acid).

5-Nitrosalicylic Acid, ≥ 98.0%

2-Hydroxy, 5-Nitro Benzoic Acid (Mnesalamine imp-N)

5-Nittro salicylic acid

96-97-9

96-97-5

C7H5O5N

Organic Building Blocks

CARBOXYLIC ACID

Building Blocks

C7

Carbonyl Compounds

Carboxylic Acids

C7

Carbonyl Compounds

Organic acids

API intermediates

Carboxylic Acids

Phenyls & Phenyl-Het

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

FINE Chemical & INTERMEDIATES