ChemicalBook > CAS DataBase List > 8-O-acetylharpagide

8-O-acetylharpagide

Product Name
8-O-acetylharpagide
CAS No.
6926-14-3
Chemical Name
8-O-acetylharpagide
Synonyms
3-Acetylharpagide;Harpagide 7-acetate;8-O-acetylharpagide;8-Acetylharpagide-RM;ACETYLHARPAGIDE, 8-O-;ACETYLHARPAGIDE, 8-O-(P);8-O-Acetylharpagide Acetylharpagi;8-O-Acetylharpagide, 10 mM in DMSO;Acetylharpagide(8-O-Acetylharpagide);8-O-Acetylharpagide Acetylharpagide
CBNumber
CB51354419
Molecular Formula
C17H26O11
Formula Weight
406.38
MOL File
6926-14-3.mol
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8-O-acetylharpagide Property

Melting point:
227-229℃
Boiling point:
607.2±55.0 °C(Predicted)
Density 
1.58
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble in DMSO and methanol;
form 
Powder
pka
11.88±0.70(Predicted)
color 
White to off-white
Water Solubility 
insoluble in water
InChIKey
CAFTUQNGDROXEZ-XBDCZORHSA-N
SMILES
CC(=O)O[C@@]1(C)C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00118
Product name
8-Acetylharpagide
Purity
≥85% (LC/MS-ELSD)
Packaging
1mg
Price
$326
Updated
2026/03/19
TRC
Product number
A178295
Product name
3-Acetylharpagide
Packaging
1mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA73988
Product name
Acetylharpagide
Packaging
10mg
Price
$120
Updated
2021/12/16
AK Scientific
Product number
W1762
Product name
8-O-Acetylharpagide
Packaging
1mg
Price
$124
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA73988
Product name
Acetylharpagide
Packaging
5mg
Price
$69
Updated
2021/12/16
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8-O-acetylharpagide Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, easily soluble in water and methanol, from the whole herb of Ajuga decumbens Thunb. in the genus Sinews, family Labiatae, and Scrophularia ningpoensis Hemsl in the family Genseng.

Uses

3-Acetylharpagide is an iridoid glycoside displaying antibacterial, antiinflammatory and antiviral effects.

Synthesis

Dried and pulverized whole grass of Solanum vulgare (3.0 kg) was soaked in acetone (20 L) at room temperature for 48 h. The filtrate was extracted three times in the same way by recovering the solvent under reduced pressure to obtain 92.0 . g acetone extract. The residue of the herb continued to be soaked in methanol (12 L) for 72 h, the filtrate was decompressed to recover the solvent, and extracted twice in the same way to obtain 222.6 g of methanol extract. g methanol extract. The acetone extract and methanol extract were combined, dissolved in 90% methanol, and extracted with hexane and dichloromethane sequentially to obtain 71.0 g of hexane extract, 30.4 of dichloromethane extract and 197.5 g of aqueous parts. The aqueous part (197.5 g) was extracted by D101 macromolecule. g) was passed through a D101 macroporous resin and eluted sequentially with water, 20%, 40%, 60% and 80% ethanol-water in a gradient to obtain the aqueous eluted site Fr.W1 (about 160 ), the 20% ethanol-water eluted site Fr. g), 20% ethanol site Fr. W2 (13.2 g), 40% ethanol site Fr. W3 (15.0 g), 60% ethanol site Fr. W4 (ca. 3.0 ) and 80% ethanol site Fr. W4 (ca. 3.0 ). g), 60% ethanol site Fr.W4 (ca. 3.0 ) and 80% ethanol site Fr.W5 (ca. 2.0 g). Fr.W2 was chromatographed on a Sephadex LH-20 column. LH-20 column chromatography, eluting with 50% methanol to give 8 flow fractions (Fr. W2a to W2h). Fr. W2d was purified by silica gel column chromatography and semi-preparative HPLC to give compound l (16.4 ). mg).

8-O-acetylharpagide Preparation Products And Raw materials

Raw materials

Preparation Products

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8-O-acetylharpagide Suppliers

Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16027
Advantage
64
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4790
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5645
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
5000
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
17301719108 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1245
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
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View Lastest Price from 8-O-acetylharpagide manufacturers

Shanghai Standard Technology Co., Ltd.
Product
8-O-Acetylharpagide 6926-14-3
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
8-O-acetylharpagide 6926-14-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
8-O-acetylharpagide 6926-14-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

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