2-Bromo-3-iodopyridine

Product Name: 2-Bromo-3-iodopyridine
CAS No.: 265981-13-3
Chemical Name: 2-Bromo-3-iodopyridine
Synonyms: Pyridine, 2-bromo-3-iodo-;2-Bromo-3-iodopyridine, CAS 265981-13-3;2-Bromo-3-iodopyridine ISO 9001：2015 REACH
CBNumber: CB51471110
Molecular Formula: C5H3BrIN
Formula Weight: 283.89
MOL File: 265981-13-3.mol

More

Less

2-Bromo-3-iodopyridine Property

Melting point:: 95-100°C
Boiling point:: 284℃
Density: 2.347
Flash point:: 126℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: -1.23±0.10(Predicted)
color: Light yellow to Brown

More

Less

Safety

Hazard Codes: Xn,N
Risk Statements: 22-41-50
Safety Statements: 26-39-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 704857
Product name: 2-Bromo-3-iodopyridine
Packaging: 1g
Price: $105
Updated: 2023/06/20

TCI Chemical

Product number: B5201
Product name: 2-Bromo-3-iodopyridine
Purity: >95.0%(GC)
Packaging: 1g
Price: $68
Updated: 2025/07/31

TCI Chemical

Product number: B5201
Product name: 2-Bromo-3-iodopyridine
Purity: >95.0%(GC)
Packaging: 5g
Price: $236
Updated: 2025/07/31

Apolloscientific

Product number: OR400475
Product name: 2-Bromo-3-iodopyridine
Packaging: 1g
Price: $35
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-S-18
Product name: 2-Bromo-3-iodopyridine
Purity: 97%
Packaging: 1g
Price: $39
Updated: 2021/12/16

More

Less

2-Bromo-3-iodopyridine Chemical Properties,Usage,Production

Synthesis

109-04-6

265981-13-3

a) Under argon protection, n-BuLi (12.78 mL, 2.5 M hexane solution, 31.96 mmol) was slowly added dropwise to a tetrahydrofuran (THF, 100 mL) solution of iPr2NH (4.44 mL, 31.96 mmol), and the reaction system was maintained at -45 °C. After stirring for 0.5 h, the reaction mixture was further cooled to -95 °C (toluene/liquid nitrogen bath), followed by the addition of 2-bromopyridine (3.02 mL, 31.65 mmol). The reaction mixture was stirred at -95 °C to -90 °C for 3 to 4 hours, then iodine (I2, 8.03 g, 31.65 mmol) was added in batches. The reaction mixture was slowly warmed to room temperature and stirred overnight. The reaction was quenched with 10% aqueous acetic acid (HOAc), the pH was adjusted to 8-9 and distilled water (50 mL) was added. The organic phase was extracted with ether and the combined organic phases were dried with anhydrous K2CO3. The solvent was removed by concentration under reduced pressure to give the crude 2-bromo-3-iodopyridine as a brown powder. The crude product was dried with KOH pellets under vacuum for 3 hours. The purity of 2-bromo-3-iodopyridine (7.66 g, 85% yield) was confirmed by 1H NMR analysis and used directly in the next reaction.1H NMR (499.93 MHz, CDCl3, 25 °C): δ = 8.05 (dd, J = 0.6, 5.2 Hz, 1H), 7.91 (dd, J = 0.6, 1.5 Hz, 1H), 7.62 ( dd, J = 1.5, 5.2 Hz, 1H). The data obtained are in agreement with those reported in the literature [17].

References

[1] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 2682 - 2688
[2] Tetrahedron Letters, 2008, vol. 49, # 17, p. 2839 - 2843
[3] Chemical Communications, 2001, # 23, p. 2450 - 2451
[4] Synthesis, 2004, # 16, p. 2614 - 2616
[5] Angewandte Chemie - International Edition, 2008, vol. 47, # 9, p. 1662 - 1667

2-Bromo-3-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Bromo-3-iodopyridine Suppliers

Americas 1 China 101 Europe 1 Germany 1 India 8 Japan 1 United Kingdom 2 United States 13 Global 128

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Reddy Chemtech Inc.

Tel: --
Fax: --
Email: sales@reddychemtech.com
Country: United States
ProdList: 224
Advantage: 0

AOBChem USA

Tel: --
Fax: --
Email: sales@aobchem.com
Country: United States
ProdList: 3487
Advantage: 50

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

More

Less

View Lastest Price from 2-Bromo-3-iodopyridine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-Bromo-3-iodopyridine 265981-13-3
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Dideu Industries Group Limited

Product: 2-Bromo-3-iodopyridine 265981-13-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

Career Henan Chemical Co

Product: 2-Bromo-3-iodopyridine 265981-13-3
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%-99%
Supply Ability: 1kg-100kg
Release date: 2020-01-07

265981-13-3, 2-Bromo-3-iodopyridineRelated Search:

2-Chloro-3-iodopyridine 2-BROMO-4,6-DIMETHYLPYRIDINE 2-CHLORO-4-IODO-3-METHYLPYRIDINE 2-Chloro-4,6-dimethylpyridine 2-Chloro-3-pyridylboronic acid 2-Bromopyridine-5-carbaldehyde 2-Bromo-4-iodopyridine 2-BROMO-3-FORMYLPYRIDINE 2-Chloro-4-iodopyridine-3-carboxaldehyde 2-BROMO-3,5-DIIODOPYRIDINE 2-BROMO-3-IODO-ISONICOTINIC ACID 2-Bromo-3-iodopyridine 2-BROMO-3-IODO-5-METHYLPYRIDINE 6-BROMO-5-IODOPYRIDIN-3-AMINE 2-BROMO-3-IODO-4,6-DIMETHYLPYRIDINE 6-BROMO-5-IODOPYRIDIN-3-OL 2-BROMO-3-IODO-5-NITROPYRIDINE 2-Bromo-3-iodo-4-methyl pyridine

Pyridine, 2-bromo-3-iodo-

2-Bromo-3-iodopyridine ISO 9001：2015 REACH

2-Bromo-3-iodopyridine, CAS 265981-13-3

265981-13-3

Propidium heterocyclic series