METHYL 2-AMINO-5-METHOXYBENZOATE
- Product Name
- METHYL 2-AMINO-5-METHOXYBENZOATE
- CAS No.
- 2475-80-1
- Chemical Name
- METHYL 2-AMINO-5-METHOXYBENZOATE
- Synonyms
- Methyl 6-amino-m-anisate;Methyl 5-methoxyanthranilate;Methyl2-amino-5-methoxybenzoate,96%;2-Amino-5-methoxybenzoic acid methyl ester;Benzoic acid, 2-aMino-5-Methoxy-, Methyl ester
- CBNumber
- CB51486729
- Molecular Formula
- C9H11NO3
- Formula Weight
- 181.19
- MOL File
- 2475-80-1.mol
METHYL 2-AMINO-5-METHOXYBENZOATE Property
- Melting point:
- 37-38℃
- Boiling point:
- 298.8±20.0 °C(Predicted)
- Density
- 1.179±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2.70±0.10(Predicted)
- Appearance
- Light brown to brown Solid
- Water Solubility
- Slightly Soluble (1.1 g/L) (25°C) in water.
Safety
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M328730
- Product name
- Methyl2-Amino-5-methoxybenzoate
- Packaging
- 10g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- OR912063
- Product name
- Methyl2-amino-5-methoxybenzoate
- Purity
- 98%
- Packaging
- 1g
- Price
- $182
- Updated
- 2021/12/16
- Product number
- OR912063
- Product name
- Methyl2-amino-5-methoxybenzoate
- Purity
- 98%
- Packaging
- 5g
- Price
- $573
- Updated
- 2021/12/16
- Product number
- CHM0122339
- Product name
- METHYL 2-AMINO-5-METHOXYBENZOATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $721.57
- Updated
- 2021/12/16
- Product number
- OR912063
- Product name
- Methyl2-amino-5-methoxybenzoate
- Purity
- 98%
- Packaging
- 10g
- Price
- $928
- Updated
- 2021/12/16
METHYL 2-AMINO-5-METHOXYBENZOATE Chemical Properties,Usage,Production
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
2327-45-9
2475-80-1
The general procedure for the synthesis of methyl 2-amino-5-methoxybenzoate from methyl 5-methoxy-2-nitrobenzoate was as follows: methyl 5-methoxy-2-nitrobenzoate (1.60 g, 7.58 mmol) was dissolved in ethyl acetate (14 mL), and 10% palladium-carbon catalyst (containing 50% water, 320 mg) was added. The reaction was stirred at 20-25°C for 3 hours under hydrogen atmosphere (0.25 MPa). Upon completion of the reaction, the palladium-carbon catalyst was removed by filtration and the solvent was removed by distillation under reduced pressure. The resulting crude product was purified by silica gel column chromatography with hexane/ethyl acetate (10:1 to 5:1) as eluent to afford methyl 2-amino-5-methoxybenzoate (1.29 g, 94% yield). The product was characterized by 1H-NMR (CDCl3), δ: 3.76 (3H, s), 3.88 (3H, s), 5.37 (2H, br), 6.63 (1H, d, J = 8.8 Hz), 6.95 (1H, dd, J = 8.8, 3.1 Hz), 7.35 (1H, d, J = 3.1 Hz).
References
[1] Patent: EP1724268, 2006, A1. Location in patent: Page/Page column 50
[2] Synlett, 2016, vol. 27, # 8, p. 1237 - 1240
[3] Patent: EP1844768, 2007, A1. Location in patent: Page/Page column 25
[4] Patent: CN106478548, 2017, A. Location in patent: Paragraph 0089; 0090; 0121; 0122; 0137; 0138
[5] Australian Journal of Chemistry, 1972, vol. 25, p. 2621 - 2629
METHYL 2-AMINO-5-METHOXYBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 2-AMINO-5-METHOXYBENZOATE manufacturers
- Product
- METHYL 2-AMINO-5-METHOXYBENZOATE 2475-80-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11