ChemicalBook > CAS DataBase List > Benzyl 2-methylpiperidine-1,2-dicarboxylate

Benzyl 2-methylpiperidine-1,2-dicarboxylate

Product Name
Benzyl 2-methylpiperidine-1,2-dicarboxylate
CAS No.
180609-56-7
Chemical Name
Benzyl 2-methylpiperidine-1,2-dicarboxylate
Synonyms
N-Cbz-piperidine-2-carboxylate;Methyl 1-Cbz-piperidine-2-carboxylate;Benzyl 2-methylpiperidine-1,2-dicarboxylate;1-benzyl 2-methyl piperidine-1,2-dicarboxylate;1,2-Piperidinedicarboxylic acid 2-methyl-1-(phenylmethyl)ester
CBNumber
CB51563897
Molecular Formula
C15H19NO4
Formula Weight
277.32
MOL File
180609-56-7.mol
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Benzyl 2-methylpiperidine-1,2-dicarboxylate Property

Boiling point:
390.4±42.0 °C(Predicted)
Density 
1.187
storage temp. 
Sealed in dry,Room Temperature
pka
-3.33±0.40(Predicted)
Appearance
Light yellow to yellow Liquid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M339075
Product name
MethylN-Cbz-piperidine-2-carboxylate
Packaging
500mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
X0396
Product name
Methyl-N-Cbz-piperidine-2-carboxylate
Packaging
100g
Price
$483
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0096319
Product name
METHYL N-CBZ-PIERIDINE-2-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$501.77
Updated
2021/12/16
AK Scientific
Product number
X0396
Product name
Methyl-N-Cbz-piperidine-2-carboxylate
Packaging
1g
Price
$62
Updated
2021/12/16
Ambeed
Product number
A212019
Product name
MethylN-Cbz-piperidine-2-carboxylate
Purity
97%
Packaging
1g
Price
$6
Updated
2021/12/16
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Benzyl 2-methylpiperidine-1,2-dicarboxylate Chemical Properties,Usage,Production

Synthesis

28697-07-6

74-88-4

180609-56-7

Example 36; 2-(2-methylpiperidin-2-yl)-1H-benzimidazole-4-carboxamide; Example 36A; 1-Benzyl-2-methylpiperidine-1,2-dicarboxylate. 1-[(Benzyloxy)carbonyl]piperidine-2-carboxylic acid (5 g) and iodomethane (2.5 mL) were dissolved in DMF (40 mL), potassium bicarbonate (3.8 g) was added, and the reaction mixture was stirred for 18 hours at room temperature. Upon completion of the reaction, the reaction mixture was concentrated and the residue was partitioned between ethyl acetate and water. The organic phase was separated, concentrated and the residue was purified by fast chromatography (silica gel, ethyl acetate/hexane as eluent) to give Example 36A (4.88 g, yield: 93%). The mass spectrum (DCI/NH3) showed m/z 278 (M + H)+.

References

[1] Patent: US2006/229289, 2006, A1. Location in patent: Page/Page column 20-21

Benzyl 2-methylpiperidine-1,2-dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Benzyl 2-methylpiperidine-1,2-dicarboxylate manufacturers

Career Henan Chemical Co
Product
Benzyl 2-methylpiperidine-1,2-dicarboxylate 180609-56-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 458
Release date
2019-09-01

180609-56-7, Benzyl 2-methylpiperidine-1,2-dicarboxylateRelated Search:


  • Benzyl 2-methylpiperidine-1,2-dicarboxylate
  • 1,2-Piperidinedicarboxylic acid 2-methyl-1-(phenylmethyl)ester
  • 1-benzyl 2-methyl piperidine-1,2-dicarboxylate
  • Methyl 1-Cbz-piperidine-2-carboxylate
  • N-Cbz-piperidine-2-carboxylate
  • 180609-56-7