2,6-Diacetylpyridine
- Product Name
- 2,6-Diacetylpyridine
- CAS No.
- 1129-30-2
- Chemical Name
- 2,6-Diacetylpyridine
- Synonyms
- 1,1'-(pyridine-2,6-diyl)bis(ethan-1-one);1,1'-(pyridine-2,6-diyl)diethanone;2,6-DiacetyL;2,6-diacetylpyrdine;2,6-DIACETYLPYRIDINE;Pyridin-2,6-diacetyl;pyridine-2,6-diacetyl;2,6-Diacetylpyridine>2,6-Diacetylpyridine,99%;2,6-Diacetylpyridine 99%
- CBNumber
- CB5182774
- Molecular Formula
- C9H9NO2
- Formula Weight
- 163.17
- MOL File
- 1129-30-2.mol
2,6-Diacetylpyridine Property
- Melting point:
- 79-82 °C (lit.)
- Boiling point:
- 126 °C / 6mmHg
- Density
- 1.2021 (rough estimate)
- refractive index
- 1.5300 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Crystalline Needles or Powder
- pka
- 0.88±0.10(Predicted)
- color
- White to off-white
- Water Solubility
- Soluble in water, chloroform, and DMSO.
- BRN
- 118286
- InChI
- InChI=1S/C9H9NO2/c1-6(11)8-4-3-5-9(10-8)7(2)12/h3-5H,1-2H3
- InChIKey
- BEZVGIHGZPLGBL-UHFFFAOYSA-N
- SMILES
- C1(C(=O)C)=NC(C(=O)C)=CC=C1
- LogP
- 1.319 (est)
- CAS DataBase Reference
- 1129-30-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,F
- Risk Statements
- 36/37/38-15-10
- Safety Statements
- 26-36-43-7/8
- WGK Germany
- 3
- F
- 10
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D8801
- Product name
- 2,6-Diacetylpyridine
- Purity
- 99%
- Packaging
- 1g
- Price
- $36.82
- Updated
- 2025/07/31
- Product number
- D8801
- Product name
- 2,6-Diacetylpyridine
- Purity
- 99%
- Packaging
- 5g
- Price
- $209
- Updated
- 2025/07/31
- Product number
- D2377
- Product name
- 2,6-Diacetylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $120
- Updated
- 2025/07/31
- Product number
- D2377
- Product name
- 2,6-Diacetylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $396
- Updated
- 2025/07/31
- Product number
- D8801
- Product name
- 2,6-Diacetylpyridine
- Purity
- 99%
- Packaging
- 25g
- Price
- $944
- Updated
- 2025/07/31
2,6-Diacetylpyridine Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline needles or powder
Uses
2,6-Diacetylpyridine is used as intermediate in organic synthesis. It is a precursor to ligands in coordination chemistry.
Application
2,6-Diacetylpyridine can be used as a starting material for the synthesis of:
Iron and cobalt bis(imino)pyridyl complexes, catalysts for ethylene oligomerization.
Thiosemicarbazone derivatives with potential application as anti-mycobacterial tuberculosis agent.
Macrocyclic pentadentate nitrogen–sulphur donor ligands by [1+1] condensation with 1,2-di(o-aminophenylthio)ethane.
Synthesis
935-28-4
1129-30-2
The general procedure for the synthesis of 2,6-diacetylpyridine from 2,6-diethylpyridine was as follows: 1.0 equiv. of N-hydroxyphthalimide (NHPI) was added to a 25 mL Schlenk reaction tube and dried under vacuum for 15 min. Subsequently, acetonitrile was added as a solvent under oxygen atmosphere, followed by 2.0 equivalents of tert-butyl nitrite and 0.5 mmol of 2,6-diethylpyridine. After sealing the reaction tube with a polytetrafluoroethylene plug, it was immersed in an oil bath preheated to 90°C for 36 hours. After completion of the reaction, the solvent acetonitrile was removed by distillation under reduced pressure. The crude product was purified by column chromatography with the eluent being petroleum ether/ethyl acetate (5:1, v/v) to give 2,6-diacetylpyridine. The product was a yellow solid in 54% yield.
References
[1] Patent: CN107011133, 2017, A. Location in patent: Paragraph 0120; 0121; 0124; 0125
[2] Organic Letters, 2017, vol. 19, # 20, p. 5593 - 5596
[3] Patent: US9266982, 2016, B2. Location in patent: Page/Page column 34
2,6-Diacetylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Diacetylpyridine Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 2,6-Diacetylpyridine manufacturers
- Product
- 2, 6-Diacetylpyridine 1129-30-2
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-24
- Product
- 2,6-Diacetylpyridine 1129-30-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000MT
- Release date
- 2024-07-17
- Product
- 2,6-Diacetylpyridine 1129-30-2
- Price
- US $0.00-0.00/Kg
- Min. Order
- 100G
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2020-01-17