10-Bromodecanoic acid
- Product Name
- 10-Bromodecanoic acid
- CAS No.
- 50530-12-6
- Chemical Name
- 10-Bromodecanoic acid
- Synonyms
- Bromocapricacid;10-Bromodecanoic;W-BROMODECANOIC ACID;1-Bromodecanoic acid;10-BROMO-DECYLIC ACID;10-BROMODECANOIC ACID;OMEGA-BROMOCAPRIC ACID;OMEGA-BROMODECANOIC ACID;Decanoic acid, 10-bromo-;10-Bromodecanoic acid 98%
- CBNumber
- CB5189571
- Molecular Formula
- C10H19BrO2
- Formula Weight
- 251.16
- MOL File
- 50530-12-6.mol
10-Bromodecanoic acid Property
- Melting point:
- 38-41 °C (lit.)
- Boiling point:
- 160 °C(Press: 1 Torr)
- Density
- 1.3099 (rough estimate)
- refractive index
- 1.5845 (estimate)
- Flash point:
- >231 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.78±0.10(Predicted)
- color
- White to Light yellow to Light orange
- Water Solubility
- Partly miscible in water.
- CAS DataBase Reference
- 50530-12-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 10-Bromodecanoic acid(50530-12-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 541397
- Product name
- 10-Bromodecanoic acid
- Purity
- 95%
- Packaging
- 5g
- Price
- $26.5
- Updated
- 2025/07/31
- Product number
- 541397
- Product name
- 10-Bromodecanoic acid
- Purity
- 95%
- Packaging
- 25g
- Price
- $54.05
- Updated
- 2025/07/31
- Product number
- B2264
- Product name
- 10-Bromodecanoic Acid
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $41
- Updated
- 2025/07/31
- Product number
- B2264
- Product name
- 10-Bromodecanoic Acid
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $129
- Updated
- 2025/07/31
- Product number
- B685323
- Product name
- 10-Bromodecanoic Acid
- Packaging
- 5g
- Price
- $55
- Updated
- 2021/12/16
10-Bromodecanoic acid Chemical Properties,Usage,Production
Chemical Properties
Flaky crystals. Melting point 42°C, boiling point 163-165°C (0.27 kPa).
Uses
10-Bromodecanoic acid may be employed as an alkylcarboxylate chain source in the preparation of alkylcarboxylate-grafted polyethylenimine. It may also be used in the synthesis of :
- 10-(methylsulfinyl)decanoic acid
- 10-cyanodecanoic acid
- (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)-decyl)triphenylphosphonium bromide
- 11-thiastearic acid
General Description
10-Bromodecanoic acid can be prepared from 10-bromodecanol via oxidation.
reaction suitability
reagent type: linker
Synthesis
53463-68-6
50530-12-6
The general procedure for the synthesis of 10-bromodecanoic acid from 10-bromo-1-decanol is as follows: 1. 48% hydrobromic acid (22.6 mL, 0.2 mol, 1 eq.) was slowly added dropwise to a toluene solution (400 mL) of 1,10-decanediol (34.8 g, 0.2 mol, 1 eq.) with stirring and refluxed for 24 hr. at 180° C. using a Dean-Stark manifold. 2. After completion of the reaction, the mixture was cooled to room temperature and washed sequentially with 6N NaOH (150 mL), 10% HCl (150 mL), water (2 x 250 mL) and brine (200 mL). 3. The organic layer was dried over anhydrous sodium sulfate and concentrated, separated by silica gel column chromatography using cyclohexane/ethyl acetate (4:1) as eluent to afford 43.5 g (92%) of 10-bromo-1-decanol as a colorless liquid. 4. To an acetone solution (130 mL) of 10-bromo-1-decanol (41 g, 0.17 mol, 1 eq.) was slowly added a chromic acid solution prepared from chromium trioxide (25.7 g, 0.26 mol, 1.5 eq.), water (25 mL), and concentrated sulfuric acid (22.5 mL, 0.34 mol, 2 eq.) at -5°C. 5. The reaction mixture was stirred at 0°C for 2 hours and then left at room temperature overnight. 6. After completion of the reaction, the mixture was extracted with ether (3 x 250 mL), washed sequentially with water (250 mL) and brine (250 mL), dried over anhydrous sodium sulfate and concentrated. 7. The residue was separated by silica gel column chromatography using dichloromethane as eluent and recrystallized from petroleum ether to give 31.0 g (73%) of 10-bromodecanoic acid as a white solid with a melting point of 36-37 °C. The residue was separated by 1H2O2 column chromatography using dichloromethane as eluent. 8. The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR δ 11.23 (bs, 1H, -OH), 3.41 (t, J = 7.0 Hz, 2H, H-10), 2.36 (t, J = 7.6 Hz, 2H, H-2), 1.87 (m, 2H, H-9), 1.64 (m, 2H, H-3), 1.22- 1.44 (m, 10H, H-3), 1.22- 2H, H-3). 1.44 (m, 10H, H-4-8); 13C NMR δ 180.2 (C1), 34.1 (C2), 34.0 (C10), 32.9, 29.1, 28.9, 28.6, 28.4, 28.2, 24.7.
References
[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 1, p. 567 - 579
[2] Patent: DE867243, 1943,
[3] Journal of the American Chemical Society, 1956, vol. 78, p. 2255,2256
[4] Journal of Organic Chemistry, 1956, vol. 21, p. 883,885
[5] Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 2000, vol. 350, p. 93 - 101
10-Bromodecanoic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from 10-Bromodecanoic acid manufacturers
- Product
- 10-Bromodecanoic Acid 50530-12-6
- Price
- US $1.70/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-22
- Product
- 10-Bromodecanoic acid 50530-12-6
- Price
- US $30.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%，95%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-03
- Product
- 10-Bromodecanoic acid 50530-12-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27