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2,3-Diaminobenzoic acid

Product Name
2,3-Diaminobenzoic acid
CAS No.
603-81-6
Chemical Name
2,3-Diaminobenzoic acid
Synonyms
3-Diaminobenzoic acid;2,3-Diaminobenzonicacid;2,3-DIAMINOBENZOIC ACID;Benzoic acid, 2,3-diamino-;2,3-bis(azanyl)benzoic acid;3-carboxy-1,2-diaminobenzene;2,3-diaMinobenzoic acid hydrochloride
CBNumber
CB5194337
Molecular Formula
C7H8N2O2
Formula Weight
152.15
MOL File
603-81-6.mol
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2,3-Diaminobenzoic acid Property

Melting point:
198-204 °C
Boiling point:
274.61°C (rough estimate)
Density 
1.2804 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
pka
5.10±0.10(Predicted)
color 
Brown to dark brown
CAS DataBase Reference
603-81-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36
Safety Statements 
26
HazardClass 
IRRITANT
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
D415025
Product name
2,3-DiaminobenzoicAcid
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
D415025
Product name
2,3-DiaminobenzoicAcid
Packaging
1g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD03094
Product name
2,3-Diaminobenzoic acid
Packaging
5G
Price
$100
Updated
2021/12/16
SynQuest Laboratories
Product number
4657-1-11
Product name
2,3-Diaminobenzoic acid
Packaging
25g
Price
$225
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD03094
Product name
2,3-Diaminobenzoic acid
Packaging
25g
Price
$300
Updated
2021/12/16
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2,3-Diaminobenzoic acid Chemical Properties,Usage,Production

Uses

2,3-Diaminobenzoic acid (23DBA) is an important organic reagent mainly used in scientific research and laboratory experiments. 23DBA can undergo polycondensation with terephthalic acid dichloro anhydride[1]. 23DBA isomer is also used in the study of luminescence mechanism of red luminescent carbon dots (RCDs)[2]. In addition, 2,3-Diaminobenzoic acid also possesses antioxidant properties that help reduce the formation of free radicals in the body. It is also used as a chelating agent that effectively binds to metal ions and prevents them from forming insoluble complexes.

Synthesis

2,3-Diaminobenzoic acid is synthesised using 3-nitroanthranilic acid as a raw material by chemical reaction. The specific synthesis steps are as follows:
2-amino-3-nitrobenzoic acid (9.36 g, 51.4 mmol) was dissolved in MeOH (100 mL) and there was added 10% Pd/C (2.0g). The reaction was stirred under H2-atmosphere (ambient pressure) until absorption ceased. The reaction was filtered through a pad of Celite and the filtrate was evaporated under reduced pressure. The product was purified by flash chromatography (CH2Cl2/MeOH 5:1) and the collected fractions were evaporated to give 2,3-Diaminobenzoic acid (5.40 g, 69%) as a dark brown solid. mp. 199 °C dec. (Litt4. 201 °C dec.). 1H NMR (300 MHz, DMSO-d6) δ 7.09 (dd, J = 8.0, 1.5 Hz, 1H), 6.67 (dd, J = 7.4, 1.5 Hz, 1H), 6.34 (dd, J = 8.0, 7.4 Hz, 2H), 6.32 (br s, 4H). 13C NMR (75 MHz, DMSO-d6) δ 170.5, 139.6, 135.6, 119.4, 117.0, 114.9, 110.3.

References

[1] V. N. ODNORALOVA. The polycondensation reaction of 2,4-diaminobenzoic acid with dichloroanhydride of terephthalic acid[J]. Fibre Chemistry, 1974. DOI:10.1007/BF00542946.
[2] LIU Y, DING H, ZHANG S, et al. Photoluminescence mechanism of red emissive carbon dots from a diaminobenzoic acid isomer?[J]. Materials Advances, 2023. DOI:10.1039/D3MA00836C.

2,3-Diaminobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Diaminobenzoic acid Suppliers

Carbosynth
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United Kingdom
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Apollo Scientific Ltd.
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Atlantic Research Chemicals Ltd.
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Manchester Organics
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ETA SCIENTIFIC Co.,Ltd
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Fluorochem Ltd
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Fluorochem Ltd.
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Eurolabs Limited
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Zerenex Molecular Limited
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Fulcrum Scientific Ltd.
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View Lastest Price from 2,3-Diaminobenzoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2,3-Diaminobenzoic acid 603-81-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-10-25
Hebei Mojin Biotechnology Co., Ltd
Product
2,3-Diaminobenzoic acid 603-81-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-26
Honest Joy Holdings Limited
Product
2,3-Diaminobenzoic acid 603-81-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.4%
Supply Ability
100 tons
Release date
2022-02-20

603-81-6, 2,3-Diaminobenzoic acidRelated Search:


  • 2,3-DIAMINOBENZOIC ACID
  • 2,3-Diaminobenzonicacid
  • 3-carboxy-1,2-diaminobenzene
  • 2,3-bis(azanyl)benzoic acid
  • 2,3-diaMinobenzoic acid hydrochloride
  • Benzoic acid, 2,3-diamino-
  • 3-Diaminobenzoic acid
  • 603-81-6
  • 603-81-0
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • pharmacetical
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Benzoic acid
  • API intermediates
  • Carboxylic Acids
  • Phenyls & Phenyl-Het