5-Amino-8-quinolinol dihydrochloride
- Product Name
- 5-Amino-8-quinolinol dihydrochloride
- CAS No.
- 21302-43-2
- Chemical Name
- 5-Amino-8-quinolinol dihydrochloride
- Synonyms
- 8-Quinolinol, 5-amino-;5-amino-8-quinolinol chloride;5-Amino-8-hydroxyquinoline2HCl;5-Amino-8-hydroxyquinoline DiHCl;5-amino-quinolin-8-ol hydrochloride;5-AMINO-8-QUINOLINOL DIHYDROCHLORIDE;5-aminoquinolin-8-ol dihydrochloride;5-amino-8-hydroxyquinoline dichloride;(8-hydroxyquinolin-1-ium-5-yl)azanium;8-Quinolinol, 5-amino-, dihydrochloride
- CBNumber
- CB5224436
- Molecular Formula
- C9H10Cl2N2O
- Formula Weight
- 233.09
- MOL File
- 21302-43-2.mol
5-Amino-8-quinolinol dihydrochloride Property
- Melting point:
- 279 °C (dec.)(lit.)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- color
- Orange to Amber to Dark red
- Water Solubility
- almost transparency
- InChI
- 1S/C9H8N2O.2ClH/c10-7-3-4-8(12)9-6(7)2-1-5-11-9;;/h1-5,12H,10H2;2*1H
- InChIKey
- VTQDJAUGGZFPOI-UHFFFAOYSA-N
- SMILES
- Cl[H].Cl[H].Nc1ccc(O)c2ncccc12
- CAS DataBase Reference
- 21302-43-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- WGK Germany
- 3
- HS Code
- 29334990
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 305529
- Product name
- 5-Amino-8-hydroxyquinoline dihydrochloride
- Purity
- 95%
- Packaging
- 5g
- Price
- $805
- Updated
- 2025/07/31
- Product number
- 305529
- Product name
- 5-Amino-8-hydroxyquinoline dihydrochloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $425
- Updated
- 2024/03/01
- Product number
- A1005
- Product name
- 5-Amino-8-hydroxyquinoline Dihydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $138
- Updated
- 2025/07/31
- Product number
- A1005
- Product name
- 5-Amino-8-hydroxyquinoline Dihydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $507
- Updated
- 2025/07/31
- Product number
- A611273
- Product name
- 5-Amino-8-hydroxyquinoline dihydrochloride
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
5-Amino-8-quinolinol dihydrochloride Chemical Properties,Usage,Production
Chemical Properties
Crystalline powder
Uses
5-Amino-8-hydroxyquinoline dihydrochloride was used in synthesis of:
- 5-acetamido-8-hydroxyquinoline hydrochloride
- 5-(p-tolylsulfonylimino)quinolin-8-one
- 5,8-quinolinesemiquinone via ferric chloride oxidation
Synthesis
Step 1: Preparation of 5-nitroso-8-hydroxyquinoline hydrochloride
A solution of NaNO2 (30 g) in water (100 ml) was added to a mixture of 8-hydroxyquinoline (58 g, 0.4 mol) in distilled water, concentrated hydrochloric acid (75 ml) and ice (200 g) at 0-4??C. The reaction mixture was kept at 0??C overnight. Within 1 hr ?? C. The reaction mixture was kept at 0?? C. overnight and then filtered by washing with cold water to give 5-nitroso-8-hydroxyquinoline hydrochloride (95%).
Step 2: Preparation of 5-amino-8-hydroxyquinoline dihydrochloride
5-Nitroso-8-hydroxyquinoline chloride (40 g) was added to a mixture of water (160 ml) and 5N-NaOH (260 ml) and heated to 40??C. Na2S2O4 (95 g) was added to the reaction mixture and the temperature was raised to 75-80??C. The reaction mixture was cooled to 50??C and 12N-HCl (250 ml) was added. The reaction mixture was then cooled to 0 ??C and filtered to give 5-amino-8-hydroxyquinoline dihydrochloride (34 g, 69%).
5-Amino-8-quinolinol dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
5-Amino-8-quinolinol dihydrochloride Suppliers
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View Lastest Price from 5-Amino-8-quinolinol dihydrochloride manufacturers
- Product
- best 5-Amino-8-quinolinol dihydrochloride 21302-43-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-13
- Product
- 5-Amino-8-quinolinol dihydrochloride 21302-43-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-02