Gemifioxacin mesylate

Product Name: Gemifioxacin mesylate
CAS No.: 210353-53-0
Chemical Name: Gemifioxacin mesylate
Synonyms: CS-775;LB-20304a;SB-265805S;LB-20304 Mesilate;GEMIFIOXACIN MESYLATE;(Z)-Gemifloxacin Mesilate;Gemifioxacin mesylate, 98.5%;Gemifloxacin Mesylate (300 mg);Gemifioxacin mesylate USP/EP/BP;Gemifloxacin,Inhibitor,inhibit,Gemifloxacin mesylate,Bacterial
CBNumber: CB5245303
Molecular Formula: C19H24FN5O7S
Formula Weight: 485.49
MOL File: 210353-53-0.mol

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Gemifioxacin mesylate Property

Melting point:: 235-2370C
storage temp.: room temp
solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form: powder
color: white to light brown
Stability:: Hygroscopic
CAS DataBase Reference: 210353-53-0(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H341Suspected of causing genetic defects

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1625
Product name: Gemifloxacin mesylate
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $105
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1625
Product name: Gemifloxacin mesylate
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $424
Updated: 2023/06/20

Cayman Chemical

Product number: 21047
Product name: Gemifloxacin (mesylate)
Purity: ≥98%
Packaging: 5mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 21047
Product name: Gemifloxacin (mesylate)
Purity: ≥98%
Packaging: 10mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 21047
Product name: Gemifloxacin (mesylate)
Purity: ≥98%
Packaging: 25mg
Price: $119
Updated: 2024/03/01

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Gemifioxacin mesylate Chemical Properties,Usage,Production

Description

Gemifloxacin is a new fluoroquinolone derivative that is active against both Grampositive and Gram-negative bacteria, and it was launched as an oral treatment for bacterial respiratory infections. Compared with other fluoroquinolones currently on the market, gemifloxacin possesses enhanced in vitro activity against Streptococcus pneumoniae, including isolates resistant to b-lactams, macrolides, and ciprofloxacin. Gemifloxacin is specifically indicated for treating community- acquired pneumonia (CAP) caused by multi-drug resistant S. pneumoniae and for treating acute bacterial exacerbations of chronic bronchitis (AECB). The recommended dose of gemifloxacin is 320 mg daily for 5 days for AECB and 320 mg daily for 7 days for CAP.

Chemical Properties

gemifloxacin mesylate is a synthetic broad-spectrum antibacterial agent for oral administration. Gemifloxacin, a compound related to the fluoroquinolone class of antibiotics, is available as the mesylate salt in the sesquihydrate form. The mesylate salt is a white to light brown solid with a molecular weight of 485.49. Gemifloxacin is considered freely soluble at neutral pH (350 μg/mL at 37oC, pH 7.0).

Originator

LG Life Sciences (S. Korea)

Uses

Third generation fluorinated quinolone antibacterial.

Definition

ChEBI: Gemifloxacin mesylate is the mesylate salt of gemifloxacin. It has a role as an antimicrobial agent and a topoisomerase IV inhibitor. It contains a gemifloxacin.

brand name

Factive

Biochem/physiol Actions

Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

Gemifioxacin mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Gemifioxacin mesylate Suppliers

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View Lastest Price from Gemifioxacin mesylate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Gemifioxacin mesylate 210353-53-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-11-01

Hebei Mojin Biotechnology Co., Ltd

Product: Gemifioxacin mesylate 210353-53-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-18

Dideu Industries Group Limited

Product: Gemifioxacin mesylate 210353-53-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-19

210353-53-0, Gemifioxacin mesylateRelated Search:

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GEMIFIOXACIN MESYLATE

7-(3-aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid mesylate

LB-20304 Mesilate

Gemifioxacin mesylate, 98.5%

CS-775

(Z)-Gemifloxacin Mesilate

LB-20304a

SB-265805S

Gemifioxacin mesylate USP/EP/BP

(Z)-7-(3-(Aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonic acid salt

Gemifloxacin,Inhibitor,inhibit,Gemifloxacin mesylate,Bacterial

Gemifloxacin Mesylate (300 mg)

210353-53-0

C18H20FN5O4CH4SO3

C19H24FN5O7S

Intermediates & Fine Chemicals

Pharmaceuticals