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3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester

Product Name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
CAS No.
35286-58-9
Chemical Name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Synonyms
Gouguside 7;Kudinoside H;Zigu-glucoside I;Ziyu-glycoside Ⅰ;Ziyuglycoside I-RM;Ulmus pumila saponin I;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester;Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-;3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I);[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
CBNumber
CB52462159
Molecular Formula
C41H66O13
Formula Weight
766.95
MOL File
35286-58-9.mol
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3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Property

Melting point:
198-202 ºC
Boiling point:
841.9±65.0 °C(Predicted)
Density 
1.35
storage temp. 
-20°C, protect from light
solubility 
Soluble in acetonitrile and methanol;
form 
powder
pka
12.52±0.70(Predicted)
color 
White
Water Solubility 
insoluble in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84269
Product name
Ziyuglycoside I
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$435
Updated
2023/06/20
Biosynth Carbosynth
Product number
MZ44395
Product name
Ziyuglycoside I
Packaging
50mg
Price
$470
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573030
Product name
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Purity
>98%,Standard References Grade
Packaging
1g
Price
$3432.3
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
107509
Product name
ZiyuglycosideI
Packaging
10mg
Price
$556
Updated
2021/12/16
ChemScene
Product number
CS-0008893
Product name
ZiyuglycosideI
Purity
98.51%
Packaging
5mg
Price
$50
Updated
2021/12/16
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3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Burnet.

Uses

Used for content determination/identification/pharmacological experiments, etc.

Biological Activity

Ziyuglycoside I, isolated from the roots of S. officinalis, has anti-wrinkle activity and increases collagen type I expression. It can be used as an active ingredient in cosmetics and induces p53-mediated cell cycle arrest and apoptosis (apoptosis), which can be used in the study of triple-negative breast cancer.

Physiological effects

Ziyuglycoside I has the functions of vasoconstriction, hemostasis and antifungal.

in vitro

Ziyuglycoside I (5-160 μM; 24 hours) reveals a marked anti-proliferation activity with an IC 50 value of 13.96 μM in MDA-MB-231 cells. Ziyuglycoside I ( 5-20 μM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 μM. Ziyuglycoside I (5-20 μM; 24 hours) induces the cleavage of caspas- 8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression.

Cell Viability Assay

Cell Line: MDA-MB-231 cells < /td>
Concentration: 5 μM, 10 μM, 20 μM, 40 μM, 80 μM, and 160 μM
Incubation Time: 24 hours
Result: Showed cytotoxicity on MDA-MB-231 cells.

Cell Cycle Analysis

Cell Line: MDA-MB-231 cells
Concentration: 5 μM, 10 μM, and 20 μM
Incubation Time: 24 hours
Result: Induced G2/M phase arrest and apoptosis on MDA-MB-231 Cells

Western Blot Analysis

Cell Line: MDA-MB-231 cells
Concentration: 5 μM, 10 μM, and 20 μM
Incubation Time: 24 hours
Result: Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways.

3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester Suppliers

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View Lastest Price from 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
ziyu-glycoside I; 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester 35286-58-9
Price
US $0.00/KG
Min. Order
1KG
Purity
60%-98% HPLC
Supply Ability
1000KG
Release date
2022-09-16
Shaanxi Dideu Medichem Co. Ltd
Product
Ziyuglycoside I 35286-58-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-16
Shanghai Standard Technology Co., Ltd.
Product
Ziyuglycoside I 35286-58-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-20

35286-58-9, 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl esterRelated Search:

Stearic acid Ziyuglycoside II roburic acid Carboxyatractyloside Pachymic acid Madecassoside ALLEOSIDE A Poricoic acid A(F) Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate Terrestrosin K Terrestrosin D IMIPRAMINE Boron triiodide Garden Burnet Root SOPHORAE FLAVESCENTIS RADIX Itd

  • Ulmus pumila saponin I
  • 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
  • Kudinoside H
  • Zigu-glucoside I
  • Gouguside 7
  • Ziyu-glycoside Ⅰ
  • Urs-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-19-hydroxy-, β-D-glucopyranosyl ester, (3β)-
  • [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
  • 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I)
  • Ziyuglycoside I-RM
  • 35286-58-9
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract