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Prasugrel Hydrochloride

Product Name
Prasugrel Hydrochloride
CAS No.
389574-19-0
Chemical Name
Prasugrel Hydrochloride
Synonyms
Prasugrel HCl;Prasugrenhydrochloride;2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride;Ridomil 72WP;Prasugrel HCI;Unii-G89jq59I13;Effient Hydrochloride;Prasugrel hydrochloric;Praugrel hydrochloride;PRASUGREL HYDROCHLORIDE
CBNumber
CB52465251
Molecular Formula
C20H20FNO3S.ClH
Formula Weight
409.907
MOL File
389574-19-0.mol
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Prasugrel Hydrochloride Property

Melting point:
>173?C (dec.)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
White to Pale Brown
InChI
InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H
InChIKey
JALHGCPDPSNJNY-UHFFFAOYSA-N
SMILES
N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl
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Safety

HS Code 
2934990002
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1554104
Product name
Prasugrel Hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
150MG
Price
$647
Updated
2025/07/31
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
10mg
Price
$60
Updated
2021/12/16
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
50mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
P5620
Product name
Prasugrel Hydrochloride
Packaging
100mg
Price
$262
Updated
2021/12/16
TRC
Product number
P701150
Product name
PrasugrelHydrochloride
Packaging
1g
Price
$690
Updated
2021/12/16
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Prasugrel Hydrochloride Chemical Properties,Usage,Production

Description

Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.

Chemical Properties

White to Off-White Solid

Uses

A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome

in vivo

In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.

IC 50

P2Y12 Receptor

Prasugrel Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Prasugrel Hydrochloride Suppliers

Heng Sheng Jiu He meditech Co.,Ltd
Tel
18766988138
Country
China
ProdList
122
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@163.com
Country
China
ProdList
283
Advantage
58
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768836
Email
1791901229@qq.com
Country
China
ProdList
6950
Advantage
52
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
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View Lastest Price from Prasugrel Hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Prasugrel hydrochloride 389574-19-0
Price
US $0.00/g
Min. Order
50g
Purity
98%min
Supply Ability
10kg
Release date
2022-12-29
Hebei Chuanghai Biotechnology Co., Ltd
Product
PRASUGREL HYDROCHLORIDE 389574-19-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-06
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Prasugrel Hydrochloride 389574-19-0
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-09-25

389574-19-0, Prasugrel HydrochlorideRelated Search:


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  • API