ChemicalBook > CAS DataBase List > VX-222

VX-222

Product Name
VX-222
CAS No.
1026785-59-0
Chemical Name
VX-222
Synonyms
VCH222;VX-222;CS-481;VCH-222;VCH 222;cis-Lomibuvir;VX-222, VCH222;VX222(Lomibuvir);Lomibuvir (VX-222;VX-222 (VCH-222, LoMibuvir)
CBNumber
CB52501168
Molecular Formula
C25H35NO4S
Formula Weight
445.61
MOL File
1026785-59-0.mol
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VX-222 Property

Boiling point:
640.5±55.0 °C(Predicted)
Density 
1.21
storage temp. 
Store at -20°C
solubility 
≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH
form 
solid
pka
3.67±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26630
Product name
Lomibuvir
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
26630
Product name
Lomibuvir
Packaging
50mg
Price
$961
Updated
2024/03/01
Cayman Chemical
Product number
26630
Product name
Lomibuvir
Packaging
10mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
26630
Product name
Lomibuvir
Packaging
25mg
Price
$513
Updated
2024/03/01
TRC
Product number
V900505
Product name
VX-222
Packaging
5mg
Price
$270
Updated
2021/12/16
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VX-222 Chemical Properties,Usage,Production

Description

Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).

Uses

VX-222, s a novel, potent and selective inhibitor of HCV polymerase .

Definition

ChEBI: 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-[(4-methylcyclohexyl)-oxomethyl]amino]-2-thiophenecarboxylic acid is a thiophenecarboxylic acid.

target

HCV RNA-dependent RNA polymerase

VX-222 Preparation Products And Raw materials

Raw materials

Preparation Products

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VX-222 Suppliers

China 66 United States 13 Global 79
JinYan Chemicals(ShangHai) Co.,Ltd.
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Jinan Trio PharmaTech Co., Ltd.
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Dalian Meilun Biotech Co., Ltd.
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Energy Chemical
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Zhengzhou convergence chemical co., LTD
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View Lastest Price from VX-222 manufacturers

Career Henan Chemical Co
Product
VX-222 1026785-59-0
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

1026785-59-0, VX-222Related Search:

Tozasertib Telaprevir VX-745 vx984 VX-661 1H-Pyrrole-2-carboxaMide, 4-[2-[(2-chloro-4-fluorophenyl)aMino]-5-Methyl-4-pyriMidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]- VX 702 AS703026 Cilengitide Tak-715 Saracatinib Veliparib PLX4032

  • VX-222
  • 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid
  • VCH 222
  • VCH222
  • VCH-222
  • VX-222, VCH222
  • VX-222 (VCH-222, LoMibuvir)
  • 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-
  • Lomibuvir (VX-222, VCH-222)
  • VCH222; VX 222; VCH 222; VCH-222;VX-222
  • VX222(Lomibuvir)
  • CS-481
  • Lomibuvir (VX-222
  • cis-Lomibuvir
  • 1026785-59-0
  • Inhibitors
  • Inhibitor