VX-222

ChemicalBook > CAS DataBase List > VX-222

Product Name: VX-222
CAS No.: 1026785-59-0
Chemical Name: VX-222
Synonyms: VCH222;VX-222;CS-481;VCH-222;VCH 222;cis-Lomibuvir;VX-222, VCH222;VX222(Lomibuvir);Lomibuvir (VX-222;VX-222 (VCH-222, LoMibuvir)
CBNumber: CB52501168
Molecular Formula: C25H35NO4S
Formula Weight: 445.61
MOL File: 1026785-59-0.mol

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VX-222 Property

Boiling point:: 640.5±55.0 °C(Predicted)
Density: 1.21
storage temp.: Store at -20°C
solubility: ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH
form: solid
pka: 3.67±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26630
Product name: Lomibuvir
Packaging: 5mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 26630
Product name: Lomibuvir
Packaging: 50mg
Price: $961
Updated: 2024/03/01

Cayman Chemical

Product number: 26630
Product name: Lomibuvir
Packaging: 10mg
Price: $230
Updated: 2024/03/01

Cayman Chemical

Product number: 26630
Product name: Lomibuvir
Packaging: 25mg
Price: $513
Updated: 2024/03/01

TRC

Product number: V900505
Product name: VX-222
Packaging: 5mg
Price: $270
Updated: 2021/12/16

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VX-222 Chemical Properties,Usage,Production

Description

Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; K_i = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC₅₀ = 5 nM).

Uses

VX-222, s a novel, potent and selective inhibitor of HCV polymerase .

Definition

ChEBI: 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-[(4-methylcyclohexyl)-oxomethyl]amino]-2-thiophenecarboxylic acid is a thiophenecarboxylic acid.

target

HCV RNA-dependent RNA polymerase

VX-222 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from VX-222 manufacturers

Career Henan Chemical Co

Product: VX-222 1026785-59-0
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-08

1026785-59-0, VX-222Related Search:

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VX-222

5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid

VCH 222

VCH222

VCH-222

VX-222, VCH222

VX-222 (VCH-222, LoMibuvir)

2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-

Lomibuvir (VX-222, VCH-222)

VCH222; VX 222; VCH 222; VCH-222;VX-222

VX222(Lomibuvir)

CS-481

Lomibuvir (VX-222

cis-Lomibuvir

1026785-59-0

Inhibitors

Inhibitor