ChemicalBook > CAS DataBase List > MK-8617

MK-8617

Product Name
MK-8617
CAS No.
1187990-87-9
Chemical Name
MK-8617
Synonyms
MK-8617;CS-2700;MK 8617;MK8617;N-[BIS(4-METHOXYPHENYL)METHYL]-6-OXO-2-PYRIDAZIN-3-YL-1H-PYRIMIDINE-5-CARBOXAMIDE;N-(bis(4-Methoxyphenyl)Methyl)-4-hydroxy-2-(pyridazin-3-yl)pyriMidine-5-carboxaMide;5-Pyrimidinecarboxamide,N-[bis(4-methoxyphenyl)methyl]-1,6-dihydro-6-oxo-2-(3-pyridazinyl)-;N-(bis(4-methoxyphenyl)methyl)-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide;MK-8617,MK 8617,HIF-PH,inhibit,Hypoxia-inducible factors,HIFs,Inhibitor,HIF/HIF Prolyl-Hydroxylase
CBNumber
CB52516065
Molecular Formula
C24H21N5O4
Formula Weight
443.45
MOL File
1187990-87-9.mol
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MK-8617 Property

Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:5.67(Max Conc. mg/mL);12.79(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.25(Max Conc. mM)
form 
A solid
pka
5.54±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M424955
Product name
MK-8617
Packaging
5mg
Price
$45
Updated
2021/12/16
TRC
Product number
M424955
Product name
MK-8617
Packaging
10mg
Price
$70
Updated
2021/12/16
TRC
Product number
M424955
Product name
MK-8617
Packaging
100mg
Price
$470
Updated
2021/12/16
ChemScene
Product number
CS-0020731
Product name
MK-8617
Purity
98.02%
Packaging
200mg
Price
$1450
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611304
Product name
MK-8617
Purity
>97%
Packaging
250mg
Price
$1802
Updated
2021/12/16
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MK-8617 Chemical Properties,Usage,Production

Uses

MK-8617 is a potent, selective and bioavailable hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) inhibitor used in the treatment of anemia.

MK-8617 Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-8617 Suppliers

China 49 India 1 United States 7 USA 1 Global 58
Nanjing Habo Medical Technology Co., Ltd.
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View Lastest Price from MK-8617 manufacturers

Career Henan Chemical Co
Product
MK-8617 1187990-87-9
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

1187990-87-9, MK-8617Related Search:

N-{4-[(2-Aminopyridin-4-yl)oxy]-3-fluorophenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide N-ACETYL-ALPHA-D-GLUCOSAMINE N-BOC-HEXAHYDRO-5-OXOCYCLOPENTA[C]PYRROLE N-BOC-6-azaspiro[3.4]octan-2-ol CP-456773 sodium N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester N-BOC-cis-4-fluoro-L-proline MG-132 SRT1720 N-(8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl-exo)-2-methylpropanamide N-Boc-3-piperidineacetic acid N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine N-Boc-exo-3-aminotropane N-Boc-endo-3-aminotropane N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE

  • N-[BIS(4-METHOXYPHENYL)METHYL]-6-OXO-2-PYRIDAZIN-3-YL-1H-PYRIMIDINE-5-CARBOXAMIDE
  • MK 8617;MK8617
  • CS-2700
  • N-(bis(4-methoxyphenyl)methyl)-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide
  • 5-Pyrimidinecarboxamide,N-[bis(4-methoxyphenyl)methyl]-1,6-dihydro-6-oxo-2-(3-pyridazinyl)-
  • MK-8617
  • N-(bis(4-Methoxyphenyl)Methyl)-4-hydroxy-2-(pyridazin-3-yl)pyriMidine-5-carboxaMide
  • MK-8617,MK 8617,HIF-PH,inhibit,Hypoxia-inducible factors,HIFs,Inhibitor,HIF/HIF Prolyl-Hydroxylase
  • 1187990-87-9