ChemicalBook > CAS DataBase List > 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

Product Name
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
CAS No.
890842-28-1
Chemical Name
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonyms
CS-1142;GSK 650394;GSK650394 (Free base);SGK inhibitor GS650394;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CBNumber
CB52518968
Molecular Formula
C25H22N2O2
Formula Weight
382.45
MOL File
890842-28-1.mol
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Property

storage temp. 
room temp
solubility 
DMSO: soluble20mg/mL, clear
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0773
Product name
GSK-650394
Purity
≥98% (HPLC)
Packaging
5mg
Price
$150
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0773
Product name
GSK-650394
Purity
≥98% (HPLC)
Packaging
25mg
Price
$598
Updated
2024/03/01
Cayman Chemical
Product number
17001
Product name
GSK650394
Purity
≥98%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
17001
Product name
GSK650394
Purity
≥98%
Packaging
10mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
17001
Product name
GSK650394
Purity
≥98%
Packaging
25mg
Price
$467
Updated
2024/03/01
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties,Usage,Production

Uses

GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.

Definition

ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.

Biochem/physiol Actions

GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.

storage

Store at RT

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Suppliers

Axon Medchem BV
Tel
--
Fax
--
Email
info@axonmedchem.com
Country
The Netherlands
ProdList
477
Advantage
30

890842-28-1, 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacidRelated Search:


  • GSK650394 (Free base)
  • 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
  • GSK 650394
  • SGK inhibitor GS650394
  • CS-1142
  • Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
  • 6-O-α-D-Glucopyranosyl-D-glucose
  • 890842-28-1
  • Inhibitors