ChemicalBook > CAS DataBase List > 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
- Product Name
- 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
- CAS No.
- 890842-28-1
- Chemical Name
- 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
- Synonyms
- CS-1142;GSK 650394;GSK650394 (Free base);SGK inhibitor GS650394;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
- CBNumber
- CB52518968
- Molecular Formula
- C25H22N2O2
- Formula Weight
- 382.45
- MOL File
- 890842-28-1.mol
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Property
- storage temp.
- room temp
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0773
- Product name
- GSK-650394
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $150
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0773
- Product name
- GSK-650394
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $598
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17001
- Product name
- GSK650394
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17001
- Product name
- GSK650394
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $198
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17001
- Product name
- GSK650394
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $467
- Updated
- 2024/03/01
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties,Usage,Production
Uses
GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.
Definition
ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.
Biochem/physiol Actions
GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.
storage
Store at RT
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Preparation Products And Raw materials
Raw materials
Preparation Products
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Suppliers
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