ChemicalBook > CAS DataBase List > NVP-BGT226

NVP-BGT226

Product Name
NVP-BGT226
CAS No.
1245537-68-1
Chemical Name
NVP-BGT226
Synonyms
CS-382;BGT226;NVP-BGT226;BGT-226 maleate;BGT226 (NVP-BGT226);NVP-BGT226 (BGT226);NVP-BGT226 (maleate);NVP-BGT226 USP/EP/BP;NVP-BGT226 (free base);BGT-226;NVP BGT226 (BGT226)
CBNumber
CB52589704
Molecular Formula
C28H25F3N6O2.C4H4O4
Formula Weight
650.6044696
MOL File
1245537-68-1.mol
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NVP-BGT226 Property

Melting point:
>215°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22142
Product name
NVP-BGT226
Purity
≥98%
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
22142
Product name
NVP-BGT226
Purity
≥98%
Packaging
5mg
Price
$146
Updated
2024/03/01
Cayman Chemical
Product number
22142
Product name
NVP-BGT226
Purity
≥98%
Packaging
10mg
Price
$274
Updated
2024/03/01
Cayman Chemical
Product number
22142
Product name
NVP-BGT226
Purity
≥98%
Packaging
25mg
Price
$632
Updated
2024/03/01
TRC
Product number
B367500
Product name
BGT226
Packaging
5mg
Price
$250
Updated
2021/12/16
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NVP-BGT226 Chemical Properties,Usage,Production

Uses

BGT 226 is a novel phosphatidyl inositol-3 kinase/mammalian target of rapamycin (PI3K/mTOR ) dual inhibitor which has shown to be effective with gefitinib in epidermal growth factor receptor (EGFR) inhibitor-sensitive non-small cell lung cancer (NSCLC) therapy.

Definition

ChEBI: BGT226 is the maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, a mTOR inhibitor and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It contains a BGT226(1+).

target

PI3Kα

NVP-BGT226 Preparation Products And Raw materials

Raw materials

Preparation Products

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NVP-BGT226 Suppliers

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Chembest Research Laboratories Limited
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View Lastest Price from NVP-BGT226 manufacturers

Career Henan Chemical Co
Product
1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt 1245537-68-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200KG
Release date
2019-07-01

1245537-68-1, NVP-BGT226Related Search:

Siremadlin NVP-BAW2881 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride NVP-BSK805 N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide TAE226 (NVP-TAE226) NVP-LCQ195 NVP-TAE684 Gefitinib Apitolisib (GDC-0980, RG7422) AVP-AEW541 Trametinib Erlotinib hydrochloride BEZ235 (NVP-BEZ235, Dactolisib)

  • 8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one Maleic acid
  • BGT-226 maleate
  • BGT226 (NVP-BGT226)
  • BGT226 (NVP-BGT226);NVP-BGT226
  • 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo
  • 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
  • BGT226
  • NVP-BGT226
  • NVP-BGT226 (BGT226)
  • CS-382
  • BGT-226;NVP BGT226 (BGT226)
  • BGT-226 (Maleic Acid Salt)
  • BGT226 maleate (NVP-BGT226 maleate)
  • NVP-BGT226 (maleate)
  • (Z)-but-2-enedioic acid,8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one
  • NVP-BGT226 (free base)
  • NVP-BGT226 USP/EP/BP
  • 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one maleate
  • BGT226 (NVP-BGT226) maleate
  • BGT226 maleate, 10 mM in DMSO
  • 1245537-68-1
  • C32H29F3N6O6
  • C28H25F3N6O2C4H4O4
  • Akt
  • mTOR
  • PI3K
  • PI3K/Akt/mTOR
  • Inhibitors