Siremadlin

Product Name: Siremadlin
CAS No.: 1448867-41-1
Chemical Name: Siremadlin
Synonyms: Siremadlin;HDM-201;CS-2787;CS-2613;NVP-HDM201;Siremadlin，HDM 201;NVP-HDM201 S-ISOMER;HDM201 (Siremadlin);Siremadlin (NVP-HDM201);HDM201 (Siremadlin) HCl
CBNumber: CB93133461
Molecular Formula: C26H24Cl2N6O4
Formula Weight: 555.41
MOL File: 1448867-41-1.mol

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Siremadlin Property

Boiling point:: 736.5±70.0 °C(Predicted)
Density: 1.47±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 56.75 mg/mL (102.18 mM)
pka: 1.33±0.29(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7654
Product name: Siremadlin
Purity: 99.82%
Packaging: 1mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-7654
Product name: Siremadlin
Purity: 99.82%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BH166424
Product name: NVP HDM 201
Packaging: 10mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-7654
Product name: Siremadlin
Purity: 99.82%
Packaging: 10mg
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: 1697DV
Product name: Siremadlin
Packaging: 10mg
Price: $286
Updated: 2021/12/16

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Siremadlin Chemical Properties,Usage,Production

Uses

Siremadlin is an oral biologic agent that is a selective inhibitor of the p53-MDM2 interaction and is being investigated for the treatment of patients with myeloid malignancies after showing single agent activity in preclinical studies. the safety profile of Siremadlin did not differ significantly between tumor types and treatment regimens.

Siremadlin Preparation Products And Raw materials

Raw materials

Preparation Products

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Siremadlin Suppliers

China 57 United States 5 Global 62

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 3915
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3420
Advantage: 58

Shanghai YuanQi Biotechnology Co., Ltd.

Tel: +86-2332782371 +86-18120098618
Email: sales@adobechem.com
Country: China
ProdList: 1250
Advantage: 50

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 991
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9440
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

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View Lastest Price from Siremadlin manufacturers

Career Henan Chemical Co

Product: (6S)-5-(5-chloro-1,2-dihydro-1-methyl-2-oxo-3-pyridinyl)-6-(4-chlorophenyl)-2-(2,4-dimethoxy-5-pyrimidinyl)-5,6-dihydro-1-(1-methylethyl)-Pyrrolo[3,4-d]imidazol-4(1H)-one 1448867-41-1
Price: US $1.00-1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg
Release date: 2019-08-31

1448867-41-1, SiremadlinRelated Search:

NVP-BAW2881 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride NVP-BSK805 NVP-BGT226 N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide TAE226 (NVP-TAE226) NVP-LCQ195 NVP-TAE684 NVP-BEZ 235

(6S)-5-(5-chloro-1,2-dihydro-1-methyl-2-oxo-3-pyridinyl)-6-(4-chlorophenyl)-2-(2,4-dimethoxy-5-pyrimidinyl)-5,6-dihydro-1-(1-methylethyl)-Pyrrolo[3,4-d]imidazol-4(1H)-one

HDM-201

NVP-HDM201

CS-2613

CS-2787

HDM201; HDM 201; HDM-201; NVP-HDM201; NVP-HDM-201; NVP-HDM 201

(S)-5-(5-chloro-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-1-isopropyl-5,6-dihydropyrrolo[3,4-d]imidazol-4(1H)-one

Siremadlin

NVP-HDM201;HDM-201;NVP-HDM-201

Pyrrolo[3,4-d]imidazol-4(1H)-one, 5-(5-chloro-1,2-dihydro-1-methyl-2-oxo-3-pyridinyl)-6-(4-chlorophenyl)-2-(2,4-dimethoxy-5-pyrimidinyl)-5,6-dihydro-1-(1-methylethyl)-, (6S)-

Siremadlin (NVP-HDM201)

NVP-HDM201 S-ISOMER

HDM201 (Siremadlin) HCl

Siremadlin，HDM 201

HDM 201,E1/E2/E3 Enzyme,MDM-2/p53,E2 conjugating enzyme,HDM201,Inhibitor,HDM-201,Siremadlin,Ubiquitin activating enzyme,E3 ligating enzyme,inhibit,E1 activating enzyme,Ubiquitin ligase,NVP-HDM201,Ubiquitin conjugating enzyme

NVP-HDM201(Siremadlin )

HDM201 (Siremadlin)

NVP-HDM201 (SIREMADLIN) (HDM-201)

1448867-41-1

C26H24Cl2N6O4