NVP-BGT226

Product Name: NVP-BGT226
CAS No.: 1245537-68-1
Chemical Name: NVP-BGT226
Synonyms: CS-382;BGT226;NVP-BGT226;BGT-226 maleate;BGT226 (NVP-BGT226);NVP-BGT226 (BGT226);NVP-BGT226 (maleate);NVP-BGT226 USP/EP/BP;NVP-BGT226 (free base);BGT-226;NVP BGT226 (BGT226)
CBNumber: CB52589704
Molecular Formula: C28H25F3N6O2.C4H4O4
Formula Weight: 650.6044696
MOL File: 1245537-68-1.mol

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NVP-BGT226 Property

Melting point:: >215°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly)
form: Solid
color: White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22142
Product name: NVP-BGT226
Purity: ≥98%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 22142
Product name: NVP-BGT226
Purity: ≥98%
Packaging: 5mg
Price: $146
Updated: 2024/03/01

Cayman Chemical

Product number: 22142
Product name: NVP-BGT226
Purity: ≥98%
Packaging: 10mg
Price: $274
Updated: 2024/03/01

Cayman Chemical

Product number: 22142
Product name: NVP-BGT226
Purity: ≥98%
Packaging: 25mg
Price: $632
Updated: 2024/03/01

TRC

Product number: B367500
Product name: BGT226
Packaging: 5mg
Price: $250
Updated: 2021/12/16

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NVP-BGT226 Chemical Properties,Usage,Production

Uses

BGT 226 is a novel phosphatidyl inositol-3 kinase/mammalian target of rapamycin (PI3K/mTOR ) dual inhibitor which has shown to be effective with gefitinib in epidermal growth factor receptor (EGFR) inhibitor-sensitive non-small cell lung cancer (NSCLC) therapy.

Definition

ChEBI: BGT226 is the maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, a mTOR inhibitor and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It contains a BGT226(1+).

target

PI3Kα

NVP-BGT226 Preparation Products And Raw materials

Raw materials

Preparation Products

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NVP-BGT226 Suppliers

China 95 India 1 United Kingdom 1 United States 20 Global 117

Chembest Research Laboratories Limited

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Jinan Trio PharmaTech Co., Ltd.

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NCE Biomedical Co.,Ltd.

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Haoyuan Chemexpress Co., Ltd.

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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AdooQ BioScience, LLC

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Shanghai Huikai Chemical Technology Co., Ltd.

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Jinan Mingya Medical Technology Co., Ltd.

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View Lastest Price from NVP-BGT226 manufacturers

Career Henan Chemical Co

Product: 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt 1245537-68-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200KG
Release date: 2019-07-01

1245537-68-1, NVP-BGT226Related Search:

Siremadlin NVP-BAW2881 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride NVP-BSK805 N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide TAE226 (NVP-TAE226) NVP-LCQ195 NVP-TAE684 Gefitinib Apitolisib (GDC-0980, RG7422) AVP-AEW541 Trametinib Erlotinib hydrochloride BEZ235 (NVP-BEZ235, Dactolisib)

8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one Maleic acid

BGT-226 maleate

BGT226 (NVP-BGT226)

BGT226 (NVP-BGT226);NVP-BGT226

8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo

1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt

BGT226

NVP-BGT226

NVP-BGT226 (BGT226)

CS-382

BGT-226;NVP BGT226 (BGT226)

BGT-226 (Maleic Acid Salt)

BGT226 maleate (NVP-BGT226 maleate)

NVP-BGT226 (maleate)

(Z)-but-2-enedioic acid,8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one

NVP-BGT226 (free base)

NVP-BGT226 USP/EP/BP

8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one maleate

BGT226 (NVP-BGT226) maleate

1245537-68-1

C32H29F3N6O6

C28H25F3N6O2C4H4O4

Akt

mTOR

PI3K

PI3K/Akt/mTOR

Inhibitors