3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- Product Name
- 3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- CAS No.
- 26308-42-9
- Chemical Name
- 3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- Synonyms
- AKOS PAO-0874;CHEMBRDG-BB 4402465;TIMTEC-BB SBB010349;ASINEX-REAG BAS 07751205;3-ETHYL-1-METHYLPYRAZOLE-5-CARBOXYLIC ACID;5-ethyl-2-methyl-3-pyrazolecarboxylic acid;5-ethyl-2-methylpyrazole-3-carboxylic acid;5-ethyl-2-methyl-pyrazole-3-carboxylic acid;5-ETHYL-2-METHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID;3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- CBNumber
- CB5261846
- Molecular Formula
- C7H10N2O2
- Formula Weight
- 154.17
- MOL File
- 26308-42-9.mol
3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Property
- Boiling point:
- 320.8±30.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.11±0.25(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B440178
- Product name
- 3-ethyl-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B440178
- Product name
- 3-ethyl-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- B440178
- Product name
- 3-ethyl-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 2317AB
- Product name
- 3-Ethyl-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 1g
- Price
- $239
- Updated
- 2021/12/16
- Product number
- 018905
- Product name
- 5-Ethyl-2-methyl-2H-pyrazole-3-carboxylic acid
- Packaging
- 500mg
- Price
- $260
- Updated
- 2021/12/16
3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
128537-26-8
26308-42-9
General procedure for the synthesis of 3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid from ethyl 3-ethyl-1-methyl-1H-pyrazole-5-carboxylate: ethyl 3-ethyl-1-methyl-1H-pyrazole-5-carboxylate (50 mmol), sodium hydroxide (150 mmol), water (120 mL), and ethanol (20 mL) were mixed, and the reaction was stirred under reflux conditions for 4-5 hours. After completion of the reaction, the reaction solution was cooled to room temperature and separated by extraction with ethyl acetate. The aqueous phase was collected and the pH was adjusted to 5-6 with dilute hydrochloric acid, acidified and left to precipitate the product. The precipitate was collected by filtration and dried to give 3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid in 4.8 g yield.
References
[1] Journal of Agricultural and Food Chemistry, 2012, vol. 60, # 6, p. 1470 - 1479
[2] Patent: CN106608873, 2017, A. Location in patent: Paragraph 0111; 0112; 0115
[3] Patent: CN106608872, 2017, A. Location in patent: Paragraph 0104; 0107
[4] Chemical Papers, 2017, vol. 71, # 11, p. 2053 - 2061
[5] European Journal of Medicinal Chemistry, 2018, vol. 149, p. 170 - 181
3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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