2-hydroxy-4-Methoxytoluene
- Product Name
- 2-hydroxy-4-Methoxytoluene
- CAS No.
- 20734-74-1
- Chemical Name
- 2-hydroxy-4-Methoxytoluene
- Synonyms
- 3-Methoxy-6-methylphenol;5-Methoxy-2-Methylphenol;2-hydroxy-4-Methoxytoluene;Phenol, 5-methoxy-2-methyl-
- CBNumber
- CB52645354
- Molecular Formula
- C8H10O2
- Formula Weight
- 138.16
- MOL File
- 20734-74-1.mol
2-hydroxy-4-Methoxytoluene Property
- Melting point:
- 44 °C
- Boiling point:
- 249-250 °C
- Density
- 1.078±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 9.93±0.10(Predicted)
- Appearance
- Off-white to yellow <44°C Solid,>44°C Liquid
- InChI
- InChI=1S/C8H10O2/c1-6-3-4-7(10-2)5-8(6)9/h3-5,9H,1-2H3
- InChIKey
- QXIOWYFFTWXSHE-UHFFFAOYSA-N
- SMILES
- C1(O)=CC(OC)=CC=C1C
Safety
- HS Code
- 2909500090
N-Bromosuccinimide Price
- Product number
- M331685
- Product name
- 5-Methoxy-2-methylphenol
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CS-W005841
- Product name
- 5-Methoxy-2-methylphenol
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- A278327
- Product name
- 5-Methoxy-2-methylphenol
- Purity
- 98%
- Packaging
- 100mg
- Price
- $13
- Updated
- 2021/12/16
- Product number
- A278327
- Product name
- 5-Methoxy-2-methylphenol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $20
- Updated
- 2021/12/16
- Product number
- A278327
- Product name
- 5-Methoxy-2-methylphenol
- Purity
- 98%
- Packaging
- 5g
- Price
- $162
- Updated
- 2021/12/16
2-hydroxy-4-Methoxytoluene Chemical Properties,Usage,Production
Synthesis Reference(s)
Tetrahedron Letters, 29, p. 3741, 1988 DOI: 10.1016/S0040-4039(00)82103-6
Synthesis
673-22-3
20734-74-1
Example 84 Steps for the synthesis of ethyl 3-[4-(5-hydroxy-2-methylphenoxy)-2-methylphenyl]-propionate: Step A Preparation of 5-methoxy-2-methylphenol A solution of 2-hydroxy-4-methoxybenzaldehyde (5.00 g, 32.86 mmol), carbon-loaded palladium (10%, 3.50 g, 3.28 mmol) in ethanol (32 mL), and acetic acid (3 mL) was placed in a reactor and the reaction mixture was stirred at 60 psi hydrogen pressure. After overnight reaction, the mixture was filtered through a diatomaceous earth pad and washed with methanol. The filtrate was concentrated under reduced pressure and the resulting crude product was purified by fast column chromatography with hexane:ethyl acetate (2:1) as eluent to give 5-methoxy-2-methylphenol (3.96 g, 87% yield). Thin layer chromatography (TLC) Rf = 0.58 (unfolding agent: hexane:ethyl acetate 2:1).1H NMR (300MHz, CDCl3) δ: 2.18 (s, 3H), 3.75 (s, 3H), 6.42 (m, 2H), 7.00 (d, 1H, J = 8.9Hz).
References
[1] Patent: WO2005/37763, 2005, A1. Location in patent: Page/Page column 130-131
[2] Tetrahedron Letters, 1988, vol. 29, # 31, p. 3741 - 3744
[3] Monatshefte fuer Chemie, 1964, vol. 95, p. 649 - 670
[4] Journal of Organic Chemistry, 1980, vol. 45, # 2, p. 208 - 212
[5] Patent: US2003/207916, 2003, A1
2-hydroxy-4-Methoxytoluene Preparation Products And Raw materials
Raw materials
Preparation Products
2-hydroxy-4-Methoxytoluene Suppliers
- Tel
- 8485655694
- sales@alchempharmtech.com
- Country
- United States
- ProdList
- 63687
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
- +1-817863-6948 +1-（817）863-6948
- sales@aceschem.com
- Country
- United States
- ProdList
- 19632
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@synthonix.com
- Country
- United States
- ProdList
- 6872
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69
View Lastest Price from 2-hydroxy-4-Methoxytoluene manufacturers
- Product
- 2-hydroxy-4-Methoxytoluene 20734-74-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09