ChemicalBook > CAS DataBase List > Cefpiramide acid

Cefpiramide acid

Product Name
Cefpiramide acid
CAS No.
70797-11-4
Chemical Name
Cefpiramide acid
Synonyms
Cefpiramido;CEFPIRAMIDE;Cefpiramidum;cefpiramide acid;Suncefal：Sepatren;Cefpiramide (300 mg);Cefpiramide (1098118);Cefpiramide acid USP/EP/BP;7-aMino-3-(1-Methyl-1-pyrroleane oniuM acids)Methyl-2-oxacepheMs-2-Carboxylic Acid Hydrochloride;7-[2-[(4-hydroxy-6-methylpyridine-3-carbonyl)-amino]-2-(4-hydroxy phenyl)-acetylamin]-3-(1-methyl-1h-tetrazole-5-thiomethyl)-8-keto-5-thiox-1-azole[4.2.0]octadiene-2-carboxylic acid
CBNumber
CB5265046
Molecular Formula
C25H24N8O7S2
Formula Weight
612.64
MOL File
70797-11-4.mol
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Cefpiramide acid Property

Melting point:
213-215° (dec)
Density 
1.75±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.62±0.50(Predicted)
color 
White
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Safety

HS Code 
2941906000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C243400
Product name
Cefpiramide
Packaging
1g
Price
$425
Updated
2021/12/16
AK Scientific
Product number
K197
Product name
Cefpiramide
Packaging
100mg
Price
$495
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
55472
Product name
Cefpiramide
Packaging
500mg
Price
$690
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
55472
Product name
Cefpiramide
Packaging
1g
Price
$850
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000448
Product name
CEFPIRAMIDE
Purity
95.00%
Packaging
10G
Price
$1334.03
Updated
2021/12/16
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Cefpiramide acid Chemical Properties,Usage,Production

Uses

Antibacterial.

Uses

Cefpiramide is used as a β-lactam antibiotic.

Definition

ChEBI: A third-generation cephalosporin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and (R)-2-{[(4-hydroxy-6-methylpyridin-3-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectiv ly, of the cephem skeleton. It has a broad spectrum of antibacterial activity.

Antimicrobial activity

A semisynthetic parenteral cephalosporin. It exhibits a broad range of activity, which includes Ps. aeruginosa, though the overall activity is rather modest. It is moderately stable to most β-lactamases but less so than ceftazidime or cefpirome.
In volunteers given 0.5 or 1 g by intravenous bolus, the mean plasma concentration shortly after injection was around 150 or 300 mg/L, respectively. There was no accumulation when the same doses were repeated every 12 h for 11 doses. It is highly bound to plasma protein (c. 95%). The mean plasma half-life is around 5 h. Less than one-quarter of the dose appears in the urine over 24 h; the rest is excreted in bile and high concentrations are found in feces. Renal impairment has little effect on elimination in patients with normal liver function.
Diarrhea may be associated with marked suppression of gut flora resulting from biliary excretion of the drug. The molecule includes a C-3 methylthiotetrazole side chain and side effects associated with that substituent are to be expected.
It is available in Japan.

Cefpiramide acid Preparation Products And Raw materials

Raw materials

4-Methylmorpholine Phenyl glycine Potassium bicarbonate Sodium chloride CARBONYL SULFIDE 1,4-Dioxane 2,6-Lutidine Isobutyl chloroformate Magnesium sulfate

Preparation Products

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Cefpiramide acid Suppliers

China 135 Europe 2 India 3 United Kingdom 5 United States 10 Global 155
Qilu Pharmaceutical Co. Ltd.
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J & K SCIENTIFIC LTD.
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XiaoGan ShenYuan ChemPharm co,ltd
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Beijing Isomersyn Technology CO;LTD
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010-82954736 13391601435
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Sinopharm Chemical Reagent Co,Ltd.
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TargetMol Chemicals Inc.
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Aikon International Limited
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PI & PI BIOTECH INC.
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View Lastest Price from Cefpiramide acid manufacturers

Guangzhou PI PI BIOTECH INC
Product
Cefpiramide 70797-11-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cefpiramide acid 70797-11-4
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kg
Release date
2021-09-22
Dideu Industries Group Limited
Product
Cefpiramide acid 70797-11-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-29

70797-11-4, Cefpiramide acidRelated Search:

Phenylhydrazine Stearic acid Citric acid PYRAZOPHOS Cefpiramide sodium Glycine Folic acid ALTRENOGEST CHLOROPHOSPHONAZO III 4-Dimethylaminopyridine 2-Hydroxypyridine Ethyl 2-(Chlorosulfonyl)acetate PHENYL VALERATE 2-Aminopyridine 3-Aminopyridine Cefapirin sodium Cefpirome Ascoric Acid

  • (6R,7R)-7-[(2R)-2-(4-hydroxyphenyl)-2-[(6-Methyl-4-oxo-1,4-dihydropyridin-3-yl)forMaMido]acetaMido]-3-{[(1-Methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]Methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-aMino-3-(1-Methyl-1-pyrroleane oniuM acids)Methyl-2-oxacepheMs-2-Carboxylic Acid Hydrochloride
  • sodium 7-[[2-(4-hydroxyphenyl)-2-[[(6-methyl-4-oxo-1H-pyridin-3-yl)-oxomethyl]amino]-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Suncefal：Sepatren
  • 7-[2-[(4-hydroxy-6-methylpyridine-3-carbonyl)-amino]-2-(4-hydroxy phenyl)-acetylamin]-3-(1-methyl-1h-tetrazole-5-thiomethyl)-8-keto-5-thiox-1-azole[4.2.0]octadiene-2-carboxylic acid
  • CEFPIRAMIDE
  • cefpiramide acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(R*)]]-
  • Cefpiramide (300 mg)
  • Cefpiramido
  • Cefpiramidum
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-[[(4-hydroxy-6-methyl-3-pyridinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
  • Cefpiramide acid USP/EP/BP
  • Cefpiramide (1098118)
  • (6R,7R)-7-((R)-2-(4-hydroxy-6-methylnicotinamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 70797-11-4
  • 156-1-43
  • 99-0-9
  • C25H24N8O7S2
  • Pharmaceutical intermediate
  • Miscellaneous