2,6-Dichloro-4-iodophenol
- Product Name
- 2,6-Dichloro-4-iodophenol
- CAS No.
- 34074-22-1
- Chemical Name
- 2,6-Dichloro-4-iodophenol
- Synonyms
- 2,6-Dichloro-4-iodophenol;Phenol, 2,6-dichloro-4-iodo-;2,6-Dichloro-4-iodophenol 98%
- CBNumber
- CB52665365
- Molecular Formula
- C6H3Cl2IO
- Formula Weight
- 288.9
- MOL File
- 34074-22-1.mol
2,6-Dichloro-4-iodophenol Property
- Melting point:
- 91-92 °C
- Boiling point:
- 278.2±40.0 °C(Predicted)
- Density
- 2.158±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 6.42±0.23(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2908190090
N-Bromosuccinimide Price
- Product number
- 096476
- Product name
- 2,6-Dichloro-4-iodophenol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $167
- Updated
- 2021/12/16
- Product number
- CS-0031438
- Product name
- 2,6-Dichloro-4-iodophenol
- Purity
- ≥98.0%
- Packaging
- 5g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- CS-0031438
- Product name
- 2,6-Dichloro-4-iodophenol
- Purity
- ≥98.0%
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- 2601-M-00
- Product name
- 2,6-Dichloro-4-iodophenol
- Packaging
- 250mg
- Price
- $92
- Updated
- 2021/12/16
- Product number
- 096476
- Product name
- 2,6-Dichloro-4-iodophenol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $370
- Updated
- 2021/12/16
2,6-Dichloro-4-iodophenol Chemical Properties,Usage,Production
Synthesis
87-65-0
34074-22-1
The general procedure for the synthesis of 2,6-dichloro-4-iodophenol from 2,6-dichlorophenol was as follows: 2,6-dichlorophenol (10 g, 61.35 mmol, 1.00 eq.) and N-iodosuccinimide (NIS, 27.6 g, 245.33 mmol, 2.00 eq.) were dissolved in methanol (100 mL) and stirred at room temperature for 1 hour. After completion of the reaction, the mixture was concentrated under reduced pressure. The concentrated residue was redissolved in ethyl acetate (50 mL) and washed with saturated saline (3 x 30 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography using petroleum ether (100%) as eluent to afford 2,6-dichloro-4-iodophenol (10.5 g, 59% yield) as a yellow solid.1H-NMR (300 MHz, CDCl3): δ 9.83 (s, 1H), 7.27 (s, 2H) ppm.
References
[1] Patent: WO2006/100026, 2006, A1. Location in patent: Page/Page column 121
[2] Synthetic Communications, 2014, vol. 44, # 14, p. 2094 - 2102
[3] Journal of the Brazilian Chemical Society, 2010, vol. 21, # 4, p. 770 - 774
[4] Synthetic Communications, 2012, vol. 42, # 16, p. 2407 - 2414
[5] Advanced Synthesis and Catalysis, 2013, vol. 355, # 14-15, p. 2936 - 2941
2,6-Dichloro-4-iodophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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