ChemicalBook > CAS DataBase List > ML167

ML167

Product Name
ML167
CAS No.
1285702-20-6
Chemical Name
ML167
Synonyms
ML167;CS-1892;ML167/ML-167;CID 44968231;NCGC00188654;ML167 USP/EP/BP;ML167 >=98% (HPLC);ML167 (CID 44968231);ML167, 10 mM in DMSO;CID44968231;NCGC00188654
CBNumber
CB52670873
Molecular Formula
C19H17N3O3
Formula Weight
335.36
MOL File
1285702-20-6.mol
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ML167 Property

Boiling point:
531.8±45.0 °C(Predicted)
Density 
1.335±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
13.84±0.10(Predicted)
color 
off-white to gray to brown
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
46
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0924
Product name
ML167
Purity
≥98% (HPLC)
Packaging
5mg
Price
$58
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0924
Product name
ML167
Purity
≥98% (HPLC)
Packaging
25mg
Price
$477
Updated
2022/05/15
Cayman Chemical
Product number
18098
Product name
ML167
Purity
≥98%
Packaging
1mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
18098
Product name
ML167
Purity
≥98%
Packaging
5mg
Price
$71
Updated
2024/03/01
Cayman Chemical
Product number
18098
Product name
ML167
Purity
≥98%
Packaging
10mg
Price
$128
Updated
2024/03/01
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ML167 Chemical Properties,Usage,Production

Description

ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50?= 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM).

Uses

ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B[1].

Definition

ChEBI: [5-[4-[(5-methyl-2-furanyl)methylamino]-6-quinazolinyl]-2-furanyl]methanol is a member of quinazolines.

target

Clk4

IC 50

CLK4: 136 nM (IC50); CLK1: 1522 nM (IC50); CLK2: 1648 nM (IC50); DYRK1B: 4420 nM (IC50); CDK3: ＞10000 nM (IC50); DYRK1A: ＞10000 nM (IC50)

References

[1] An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program

ML167 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML167 Suppliers

China 65 United Kingdom 1 United States 14 Global 80
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-846993838003-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3248
Advantage
55
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9863
Advantage
58
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
1250
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4762
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
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60

1285702-20-6, ML167Related Search:

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  • ML167
  • ML167/ML-167
  • 5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol
  • CID 44968231
  • 5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol ML167
  • NCGC00188654
  • (5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol
  • CID44968231;NCGC00188654
  • CS-1892
  • ML167; ML-167; ML 167; CID 44968231
  • ML167 >=98% (HPLC)
  • ML167 USP/EP/BP
  • ML167 (CID 44968231)
  • (5-(4-(((5-methylfuran-2-yl)methyl)imino)-3,4-dihydroquinazolin-6-yl)furan-2-yl)methanol
  • ML 167,Inhibitor,furan ring,cell permeability,ML167,CDK,NCGC 00188654,ML-167,CID-44968231,inhibit,CID 44968231,NCGC-00188654,Caco-2 cells,Cyclin dependent kinase
  • 2-Furanmethanol, 5-[4-[[(5-methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-
  • ML-167, Cdc2-like kinase 4 inhibitor
  • ML167, 10 mM in DMSO
  • 1285702-20-6
  • Inhibitors