TG003
- Product Name
- TG003
- CAS No.
- 300801-52-9
- Chemical Name
- TG003
- Synonyms
- CS-955;CS-1704;(E/Z)-TG003;TG003/TG-003;TG003 USP/EP/BP;Cdc2-Like Kinase Inhibitor, TG003;1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone;2-Propanone,1-(3-ethyl-5-Methoxy-2(3H)-benzothiazolylidene)-;1-(3-Ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one;(1Z)-1-(3-Ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one
- CBNumber
- CB5505045
- Molecular Formula
- C13H15NO2S
- Formula Weight
- 249.33
- MOL File
- 300801-52-9.mol
TG003 Property
- Melting point:
- 132-132.5 °C
- Boiling point:
- 386.0±42.0 °C(Predicted)
- Density
- 1.237±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 33 mg/mL
- pka
- -1.76±0.20(Predicted)
- form
- solid
- color
- pale yellow
- Sensitive
- Light Sensitive
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- T5575
- Product name
- TG003
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $196
- Updated
- 2024/03/01
- Product number
- T5575
- Product name
- TG003
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $778
- Updated
- 2024/03/01
- Product number
- J64690
- Product name
- Cdc2-Like Kinase Inhibitor, TG003
- Packaging
- 5mg
- Price
- $85.1
- Updated
- 2023/06/20
- Product number
- J64690
- Product name
- Cdc2-Like Kinase Inhibitor, TG003
- Packaging
- 50mg
- Price
- $551
- Updated
- 2023/06/20
- Product number
- 10398
- Product name
- TG003
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $23
- Updated
- 2024/03/01
TG003 Chemical Properties,Usage,Production
Description
Cdc2-
Uses
TG003 has been used in PAC1 cell culture and in vitro kinase assays.
Uses
Cdc2-Like Kinase Inhibitor, TG003 is a benzothiazole agent that acts as a specific and ATP-competitive inhibitor of Clk family members. Reports show that TG003 modifies the regulation of alternative splicing modulated by phosphorylation of SR proteins in vitro, and rescues defects in the development of Xenopus caused by an overabundance of Clk activity.
Uses
TG003 can be used as a potent CDC-2 kinase inhibitor, allowing for research into identification of signaling pathways and possible therapeutic treatments.
Biochem/physiol Actions
TG003, a CLK (cdc2-like kinase) family inhibitor is used as a drug for duchenne muscular dystrophy.
TG003 Preparation Products And Raw materials
Raw materials
Preparation Products
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