ChemicalBook > CAS DataBase List > L-alpha-Cyclohexylglycine

L-alpha-Cyclohexylglycine

Product Name
L-alpha-Cyclohexylglycine
CAS No.
14328-51-9
Chemical Name
L-alpha-Cyclohexylglycine
Synonyms
L-CHG-OH;EOS-60419;-(+)-2-CycL;L-Chg-OH·HCl;H-CHG-OH TFA;L-Chg-OH·TFA;H-CHG-OH HCL;H-CHG-OET HCL;H-L-Chg-OH*HCl;L-Cyclohexyglycine
CBNumber
CB5273131
Molecular Formula
C8H15NO2
Formula Weight
157.21
MOL File
14328-51-9.mol
More
Less

L-alpha-Cyclohexylglycine Property

Melting point:
256°C
alpha 
34.5 º (c=1, 1N HCl 25 ºC)
Boiling point:
292.8±23.0 °C(Predicted)
Density 
1.120±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
2.44±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Soluble
InChI
InChI=1/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/s3
InChIKey
WAMWSIDTKSNDCU-ZETCQYMHSA-N
SMILES
C1(CCCCC1)[C@H](N)C(=O)O |&1:6,r|
CAS DataBase Reference
14328-51-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25
HS Code 
29224999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C2569
Product name
L-2-Cyclohexylglycine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$37
Updated
2025/07/31
TCI Chemical
Product number
C2569
Product name
L-2-Cyclohexylglycine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$203
Updated
2023/06/20
TRC
Product number
C987345
Product name
L-α-cyclohexylglycine
Packaging
250mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC43992
Product name
L-a-Cyclohexylglycine
Packaging
100g
Price
$125
Updated
2021/12/16
Activate Scientific
Product number
AS23043
Product name
L-(+)-2-Cyclohexylglycine
Purity
98% ee
Packaging
100g
Price
$191
Updated
2021/12/16
More
Less

L-alpha-Cyclohexylglycine Chemical Properties,Usage,Production

Chemical Properties

white to slightly beige powder

Uses

L-Alpha-cyclohexylglycine is used in the preparation of α-aminoalkanoic acids.

Synthesis

2935-35-5

14328-51-9

The general procedure for the synthesis of L-(+)-2-cyclohexylglycine from L-phenylglycine is as follows: the selective hydrogenation of optically active phenyl amino acids is carried out in a 100 ml stainless steel autoclave equipped with a magnetic stirring device. Prior to the addition of catalyst, the autoclave is purged three times with hydrogen gas to remove air completely. Under the protection of inert atmosphere, a suspension of freshly prepared nanoruthenium(at)lithium montmorillonite catalyst (containing 0.01592 mmol Ru, dissolved in 10 ml of H2O) was carefully transferred to the autoclave together with an appropriate amount of substrate, and then the autoclave was charged with hydrogen gas to a set pressure. The autoclave was placed in a preheated heating jacket, magnetic stirring was activated, and the reaction lasted for the specified time. At the end of the reaction, the autoclave was allowed to cool to room temperature and the internal pressure was slowly released. Thoroughly rinse the inside of the reactor with 2N NaOH solution to recover the products (if the reaction system is acidic, switch to 2N HCl solution). All collected solutions were filtered through a 0.22 μm PTFE membrane to remove the catalyst residue, followed by adjusting the pH of the filtrate with dilute HCl (or NaOH) solution to 5.5, at which point the products partially precipitated. The suspension was concentrated to 10 ml under vacuum to induce complete precipitation of the product. The precipitate was collected by filtration, washed with distilled water and finally dried under vacuum for 24 hours.

References

[1] Organic Process Research and Development, 2003, vol. 7, # 2, p. 164 - 167
[2] Journal of Organometallic Chemistry, 2016, vol. 812, p. 81 - 86
[3] Synthetic Communications, 1999, vol. 29, # 24, p. 4327 - 4332
[4] Journal of Medicinal Chemistry, 1993, vol. 36, # 1, p. 166 - 172

L-alpha-Cyclohexylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

L-alpha-Cyclohexylglycine Suppliers

Americas 1 Belgium 1 Canada 1 China 222 Europe 3 France 1 Germany 7 India 7 Japan 5 Switzerland 5 United Kingdom 6 United States 39 Global 298
Jinan zhongdaoanran chemical Co;Ltd
Tel
18678233466
Email
122574856@qq.com
Country
China
ProdList
90
Advantage
58
Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
375
Advantage
55
Shandong Shining Pharm Co.,Ltd
Tel
18866891188
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
172
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94644
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Chiral Chemicals Inc.
Tel
021-37285021 13472570865
Fax
86-021-51714507
Email
tym7xi@aliyun.com
Country
China
ProdList
308
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Hongbang Pharmaceutical Co., Ltd.
Tel
021-021-64975436 18917636693
Fax
021-24280809
Email
1377976036@qq.com
Country
China
ProdList
308
Advantage
55
YangZhou Ruihong Biotech Co., Ltd.
Tel
0514-015380367604 15380367604
Fax
0514-83828236
Email
sales@ruibobiotech.com
Country
China
ProdList
511
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai D&B Biological Science and Technology Co.Ltd
Tel
400-008-9730,021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3057
Advantage
60
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
158-05183379 15805183379
Fax
86-025-58905816
Email
zjp@redwood.com.cn
Country
China
ProdList
217
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4613
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4942
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Hangzhou XunDa Bio-Technology Co., Ltd.
Tel
0571-86932585
Fax
0571-86932585
Email
xuandasales@163.com
Country
China
ProdList
41
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
More
Less

View Lastest Price from L-alpha-Cyclohexylglycine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-CHG-OH 14328-51-9
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-08-31
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
H-Chg-OH 14328-51-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T+
Release date
2023-09-21
Zhuozhou Wenxi import and Export Co., Ltd
Product
L-alpha-Cyclohexylgycine 14328-51-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

14328-51-9, L-alpha-Cyclohexylglycine Related Search:

(Aminomethyl)cyclohexane Diethylstilbestrol Glycine Folic acid Molasses Hyaluronic acid Cyclohexanecarboxylic acid Ethyl 2-(Chlorosulfonyl)acetate Isocyanatocyclohexane 3-CYCLOHEXYL-L-ALANINE HYDRATE L-Homocyclohexyl alanine Citric acid α-Lipoic Acid Ascoric Acid Zabicipril Cbz-Cyclohexyl-L-glycine H-ASP-OTBU BOC-L-ALPHA-CYCLOHEXYLGLYCINE,N-tert-Butoxycarbonyl-L-ALPHA-cyclohexylglycine

  • (S)-CYCLOHEXYLGLYCINE HCL
  • H-L-Cyclohexyl-Gly-OH·TFA
  • L-2-Cyclohexylglycine trifluoroacetate≥ 99% (TLC)
  • L-Chg-OH·TFA
  • H-Cyclohexyl-L-Gly-OH·HCl
  • L-(+)-2-Cyclohexylglycine hydrochloride≥ 99% (Titration)
  • L-Chg-OH·HCl
  • L-Cyclohexylglycine,99%e.e.
  • H-CHG-OH TFA
  • H-PHG(HEXAHYDRO)-OH HCL
  • H-CYCLOHEXYL-GLY-OH HCL
  • H-CYCLOHEXYL-GLY-OH TFA
  • H-CHG-OH HCL
  • HEXAHYDRO-L-PHENYLGLYCINE HYDROCHLORIDE
  • H-L-Chg-OH*HCl
  • H-Cyclohexyl-Gly-OH (H-Chg-OH: L-2-Cyclohexylglycine)
  • L-alpha-Cyclohexylglycine,97%
  • H-Cyclohexyl-Gly-OH (H-Chg-OH
  • (S)-Cyclohexylglycine hydrochloride
  • L-2-CYCLOHEXYLGLYCINE HYDROCHLORIDE
  • L-2-CYCLOHEXYLGLYCINE TRIFLUOROACETATE
  • L-ALPHA-CYCLOHEXYLGLYCINE HYDROCHLORIDE SALT
  • L-ALPHA-CYCLOHEXYLGYCINE HYDROCHLORIDE SALT
  • L-CYCLOHEXYLGLYCINE HYDROCHLORIDE
  • L-Cyclohexyglycine
  • L-CYCLOHEXYLGLYCINE 98%
  • L-a-cyclobenzyl glycine
  • (S)-(-)-alpha-Aminocyclohexylacetic acid
  • L-alpha-Cyclohexylglycine
  • AMINO-CYCLOHEXYL-ACE
  • L-alpha-Cyclohexylglycine, 97% 5GR
  • H-CHG-OET HCL
  • (S)-alpha-Aminocyclohexylacetic Acid H-Chg-OH
  • L-Cyclohexylglycine, H-Chg-OH
  • L-CHG-OH
  • Cyclohexaneacetic acid,a-aMino-, (aS)-
  • L-(+)-2-Cyclohexylglycine, 95+%
  • EOS-60419
  • L-2-Cyclohexylglycine &gt
  • Cyclohexaneacetic acid, α-amino-, (αS)-
  • -(+)-2-CycL
  • L-alpha-Cyclohexylglycine USP/EP/BP
  • L-alpha-Cyclohexylgycine
  • L-α-cyclohexylglycine
  • (αS)-α-Aminocyclohexaneacetic acid
  • (alphaS)-alpha-Aminocyclohexaneacetic acid
  • 14328-51-9
  • Glycine [Gly, G]
  • API
  • pharmacetical