L-alpha-Cyclohexylglycine
- Product Name
- L-alpha-Cyclohexylglycine
- CAS No.
- 14328-51-9
- Chemical Name
- L-alpha-Cyclohexylglycine
- Synonyms
- L-CHG-OH;EOS-60419;-(+)-2-CycL;L-Chg-OH·HCl;H-CHG-OH TFA;L-Chg-OH·TFA;H-CHG-OH HCL;H-CHG-OET HCL;H-L-Chg-OH*HCl;L-Cyclohexyglycine
- CBNumber
- CB5273131
- Molecular Formula
- C8H15NO2
- Formula Weight
- 157.21
- MOL File
- 14328-51-9.mol
L-alpha-Cyclohexylglycine Property
- Melting point:
- 256°C
- alpha
- 34.5 º (c=1, 1N HCl 25 ºC)
- Boiling point:
- 292.8±23.0 °C(Predicted)
- Density
- 1.120±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 2.44±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- Soluble
- InChI
- InChI=1/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/s3
- InChIKey
- WAMWSIDTKSNDCU-ZETCQYMHSA-N
- SMILES
- C1(CCCCC1)[C@H](N)C(=O)O |&1:6,r|
- CAS DataBase Reference
- 14328-51-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-24/25
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- C2569
- Product name
- L-2-Cyclohexylglycine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- C2569
- Product name
- L-2-Cyclohexylglycine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $203
- Updated
- 2023/06/20
- Product number
- C987345
- Product name
- L-α-cyclohexylglycine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- P968
- Product name
- L-alpha-Cyclohexylglycine
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 14318
- Product name
- L-2-Cyclohexylglycine,98%(Assay)
- Purity
- 98%(Assay)
- Packaging
- 1G
- Price
- $14
- Updated
- 2021/12/16
L-alpha-Cyclohexylglycine Chemical Properties,Usage,Production
Chemical Properties
white to slightly beige powder
Uses
L-Alpha-cyclohexylglycine is used in the preparation of α-aminoalkanoic acids.
Synthesis
2935-35-5
14328-51-9
The general procedure for the synthesis of L-(+)-2-cyclohexylglycine from L-phenylglycine is as follows: the selective hydrogenation of optically active phenyl amino acids is carried out in a 100 ml stainless steel autoclave equipped with a magnetic stirring device. Prior to the addition of catalyst, the autoclave is purged three times with hydrogen gas to remove air completely. Under the protection of inert atmosphere, a suspension of freshly prepared nanoruthenium(at)lithium montmorillonite catalyst (containing 0.01592 mmol Ru, dissolved in 10 ml of H2O) was carefully transferred to the autoclave together with an appropriate amount of substrate, and then the autoclave was charged with hydrogen gas to a set pressure. The autoclave was placed in a preheated heating jacket, magnetic stirring was activated, and the reaction lasted for the specified time. At the end of the reaction, the autoclave was allowed to cool to room temperature and the internal pressure was slowly released. Thoroughly rinse the inside of the reactor with 2N NaOH solution to recover the products (if the reaction system is acidic, switch to 2N HCl solution). All collected solutions were filtered through a 0.22 μm PTFE membrane to remove the catalyst residue, followed by adjusting the pH of the filtrate with dilute HCl (or NaOH) solution to 5.5, at which point the products partially precipitated. The suspension was concentrated to 10 ml under vacuum to induce complete precipitation of the product. The precipitate was collected by filtration, washed with distilled water and finally dried under vacuum for 24 hours.
References
[1] Organic Process Research and Development, 2003, vol. 7, # 2, p. 164 - 167
[2] Journal of Organometallic Chemistry, 2016, vol. 812, p. 81 - 86
[3] Synthetic Communications, 1999, vol. 29, # 24, p. 4327 - 4332
[4] Journal of Medicinal Chemistry, 1993, vol. 36, # 1, p. 166 - 172
L-alpha-Cyclohexylglycine Preparation Products And Raw materials
Raw materials
Preparation Products
L-alpha-Cyclohexylglycine Suppliers
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View Lastest Price from L-alpha-Cyclohexylglycine manufacturers
- Product
- L-CHG-OH 14328-51-9
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2021-08-31
- Product
- H-Chg-OH 14328-51-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1T+
- Release date
- 2023-09-21
- Product
- L-alpha-Cyclohexylgycine 14328-51-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10