ChemicalBook > CAS DataBase List > Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate

Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate

Product Name
Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate
CAS No.
902589-96-2
Chemical Name
Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate
Synonyms
YMU1;Thymidylate Kinase Inhibitor, YMU1;Thymidylate Kinase Inhibitor, YMU1 - CAS 902589-96-2 - Calbiochem;Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate;YMU 1,inhibit,YMU-1,YMU1,Thymidylate Kinase Inhibitor, YMU1,Inhibitor,Thymidylate Kinase Inhibitor, YMU-1;4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester;1-Piperazinecarboxylic acid, 4-[2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-, ethyl ester
CBNumber
CB52751080
Molecular Formula
C17H22N4O4S
Formula Weight
378.45
MOL File
902589-96-2.mol
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Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate Property

storage temp. 
2-8°C
solubility 
DMSO: soluble1mg/mL, clear (warmed)
form 
White solid
color 
white to light brown
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0815
Product name
YMU1
Purity
≥98% (HPLC)
Packaging
5mg
Price
$94.3
Updated
2024/03/01
Sigma-Aldrich
Product number
606015
Product name
Thymidylate Kinase Inhibitor, YMU1
Packaging
10mg
Price
$154
Updated
2023/01/07
Cayman Chemical
Product number
21981
Product name
YMU1
Packaging
5mg
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
21981
Product name
YMU1
Packaging
10mg
Price
$134
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0815
Product name
YMU1
Purity
≥98% (HPLC)
Packaging
25mg
Price
$478
Updated
2024/03/01
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Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate Chemical Properties,Usage,Production

Uses

YMU1 is a potent, reversible, and ATP-competitive inhibitor of human Thymidylate kinase (TMPK).

Biological Activity

YMU1 is a cell-permeable and nontoxic inhibitor of hTMPK (thymidylate kinase) th at sensitizes tumor cells to doxorubicin in vitro and in vivo.

Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate Suppliers

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902589-96-2, Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylateRelated Search:

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  • 4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester
  • Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate
  • YMU1
  • Thymidylate Kinase Inhibitor, YMU1
  • Thymidylate Kinase Inhibitor, YMU1 - CAS 902589-96-2 - Calbiochem
  • 1-Piperazinecarboxylic acid, 4-[2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-, ethyl ester
  • YMU 1,inhibit,YMU-1,YMU1,Thymidylate Kinase Inhibitor, YMU1,Inhibitor,Thymidylate Kinase Inhibitor, YMU-1
  • 902589-96-2