1-Iodobutane Property

Melting point:

−103 °C(lit.)

Boiling point:

130-131 °C(lit.)

Density 

1.617 g/mL at 25 °C(lit.)

vapor density 

~5 (vs air)

vapor pressure 

18.5 hPa (25 °C)

refractive index 

n20/D 1.498(lit.)

Flash point:

92 °F

storage temp. 

Store below +30°C.

solubility 

alcohol: soluble

form 

Liquid

color 

Clear colorless to pale yellow or light pink

Water Solubility 

Insoluble in water.

Sensitive 

Light Sensitive

Merck 

14,1573

BRN 

1420755

Dielectric constant

4.5（130℃）

Stability:

Stable. Highly flammable. Incompatible with strong oxidizing agents. Light sensitive.

CAS DataBase Reference

542-69-8(CAS DataBase Reference)

NIST Chemistry Reference

Butane, 1-iodo-(542-69-8)

EPA Substance Registry System

Butane, 1-iodo- (542-69-8)

Safety

Hazard Codes 

Xn

Risk Statements 

10-20-36/37/38-20/22

Safety Statements 

16-36-36/37/39-26

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

EK4400000

F 

8

Hazard Note 

Harmful

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29033080

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H331Toxic if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

1-Iodobutane Chemical Properties,Usage,Production

Chemical Properties

colorless liquid. Soluble in chloroform, miscible with ethanol and ether, insoluble in water, and will change color when exposed to light or left for a long time.

Uses

1-Iodobutane was used in the synthesis of S-alkylated 5-(2-,3- and 4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol and 5-(2-,3- and 4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazole-3-thiol. It is also used in wide range of medicals industrial applications as well as in human and animal nutrition products, pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.

Preparation

1-Iodobutane is obtained by reacting n-butanol with iodine in the presence of phosphorus.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 2048, 1979 DOI: 10.1021/jo01326a042
Synthesis, p. 114, 1976

General Description

Thermal chemistry of 1-iodobutane has been investigated on clean and hydrogen- and deuterium-predosed Pt(111) single-crystal surfaces by temperature-programmed desorption and reflection-absorption infrared spectroscopy.

Purification Methods

Dry the iodide with MgSO4 or P2O5, fractionally distil it through a column packed with glass helices, taking the middle fraction and storing over calcium or mercury in the dark. Alternatively purify it by prior passage through activated alumina or by shaking with conc H2SO4 then washing with Na2SO3 solution. It has also been treated carefully with sodium to remove free HI and H2O, before distilling through a column containing copper turnings at the top. Another purification procedure consisted of treatment with bromine, followed by extraction of free halogen with Na2S2O3, washing with H2O, drying and fractionally distilling. [Beilstein 1 IV 271.]