2-Carboxyphenylboronic acid
- Product Name
- 2-Carboxyphenylboronic acid
- CAS No.
- 149105-19-1
- Chemical Name
- 2-Carboxyphenylboronic acid
- Synonyms
- BM403;2-CarboxyphenyL;RARECHEM AH PB 0146;2-Carboxyphenylboron;2-BORONOBENZOIC ACID;Benzoic acid, 2-borono-;Florfenicol Impurity 35;2-CarboxyphenylboronicAci;O-CARBOXYPHENYLBORONIC ACID;2-CARBOXYPHENYLBORONIC ACID
- CBNumber
- CB5283710
- Molecular Formula
- C7H7BO4
- Formula Weight
- 165.94
- MOL File
- 149105-19-1.mol
2-Carboxyphenylboronic acid Property
- Melting point:
- 138-141°C
- Boiling point:
- 412.3±47.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 4.27±0.36(Predicted)
- color
- White to Almost white
- BRN
- 2835407
- InChIKey
- KWNPRVWFJOSGMZ-UHFFFAOYSA-N
- CAS DataBase Reference
- 149105-19-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22-36/37
- Safety Statements
- 26-36/37/39-36
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS004617
- Product name
- 2-carboxyphenylboronic acid
- Purity
- AldrichCPR
- Packaging
- 100MG
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- C2501
- Product name
- 2-Carboxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- C2501
- Product name
- 2-Carboxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $145
- Updated
- 2025/07/31
- Product number
- C181380
- Product name
- 2-Carboxyphenylboronicacid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB117163
- Product name
- 2-Boronobenzoic acid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
2-Carboxyphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
2-Carboxyphenylboronic acid is used in the studies on a new class of carbohydrate-binding boronic acids called the boronophthalide; a sugar-binding boronic acids that is soluble and capable of complexing glycosides in neutral water.
Synthesis
124-38-9
1229227-01-3
149105-19-1
The o-bromophenylboronic acid trimer was dissolved in 600 mL of anhydrous tetrahydrofuran under nitrogen protection. After homogenization, the solution was transferred to a 2 L three-neck flask and cooled to -10 °C. Under the condition of maintaining temperature, 1.2 L of 1 M isopropylmagnesium chloride solution (1.2 moles) was added slowly and dropwise. After the dropwise addition, the reaction was continued to be stirred at -10 °C for 1-3 hours. Subsequently, the reaction system was allowed to warm up naturally to room temperature and stirring was continued for 2-5 hours. The reaction system was cooled to 0 °C again, dry ice was added in three batches, the reaction was stirred and the reaction progress was monitored by TLC. Upon completion of the reaction, the reaction was quenched with 15% aqueous hydrochloric acid, the pH was adjusted to 1-2, and stirring was continued for 3-5 hours at room temperature to ensure complete hydrolysis of the trimer. After precipitation of the solid, it was filtered and recrystallized from a mixed solvent of water and ethanol to give 81.4 g of white solid o-carboxyphenylboronic acid with HPLC purity of 98.4%. The overall yield of the two-step reaction was 49%.
References
[1] Patent: CN104844643, 2017, B. Location in patent: Paragraph 0032; 0033
2-Carboxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Carboxyphenylboronic acid manufacturers
- Product
- 2-Carboxyphenylboronic acid 149105-19-1
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2-Carboxyphenylboronic acid 149105-19-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-Carboxyphenylboronic acid 149105-19-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09