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trans-Cyclooctene-maleimide

Product Name
trans-Cyclooctene-maleimide
CAS No.
1609659-01-9
Chemical Name
trans-Cyclooctene-maleimide
Synonyms
TCO-PEG3-maleimide;(4E)-TCO-PEG3-Maleimide;trans-Cyclooctene-maleimide;Trans-Cyclooctene-PEG3-Maleimide,TCO-PEG3-Maleimide;6,9,12-Trioxa-2,16-diazanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 4-cycloocten-1-yl ester
CBNumber
CB52925335
Molecular Formula
C26H41N3O8
Formula Weight
523.62
MOL File
1609659-01-9.mol
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trans-Cyclooctene-maleimide Property

Boiling point:
717.1±60.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
12.38±0.46(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
790443
Product name
TCO-PEG3-maleimide
Packaging
5mg
Price
$278
Updated
2024/03/01
Sigma-Aldrich
Product number
790443
Product name
TCO-PEG3-maleimide
Packaging
25mg
Price
$411
Updated
2024/03/01
Chem-Impex
Product number
35085
Product name
TCO-PEG3-maleimide,97%(HPLC)
Purity
97%(HPLC)
Packaging
5MG
Price
$112
Updated
2021/12/16
Chem-Impex
Product number
35085
Product name
TCO-PEG-maleimide
Purity
≥ 95% (HPLC)
Packaging
25MG
Price
$250
Updated
2021/12/16
Iris Biotech GmbH
Product number
TCO1050
Product name
TCO-PEG(3)-mal
Packaging
25mg
Price
$573.75
Updated
2021/12/16
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trans-Cyclooctene-maleimide Chemical Properties,Usage,Production

Biochem/physiol Actions

Maleimide (thiol reactive) functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into thiol containing compounds or biomolecules. Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. The PEG spacer allows for increased water solubility; less aggregation and an increased distance between the thiol to be modified and the reactive alkene.

trans-Cyclooctene-maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

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trans-Cyclooctene-maleimide Suppliers

Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
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View Lastest Price from trans-Cyclooctene-maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
(4E)-TCO-PEG3-Maleimide 1609659-01-9
Price
US $0.00/mg
Min. Order
5mg
Purity
>95.00%
Supply Ability
5mg
Release date
2024-03-21

1609659-01-9, trans-Cyclooctene-maleimideRelated Search:


  • TCO-PEG3-maleimide
  • trans-Cyclooctene-maleimide
  • (4E)-TCO-PEG3-Maleimide
  • Trans-Cyclooctene-PEG3-Maleimide,TCO-PEG3-Maleimide
  • 6,9,12-Trioxa-2,16-diazanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 4-cycloocten-1-yl ester
  • 1609659-01-9
  • C26H41N3O8