ChemicalBook > CAS DataBase List > 3-(Methylthio)propionaldehyde

3-(Methylthio)propionaldehyde

Product Name
3-(Methylthio)propionaldehyde
CAS No.
3268-49-3
Chemical Name
3-(Methylthio)propionaldehyde
Synonyms
METHIONAL;MMP;3-(METHYLTHIO)PROPANAL;3-(Methylsulfanyl)propanal;4-THIAPENTANAL;3-Methyl propionaldehyde;C4H8SO;3-(methylthiol)propanal;3-(methylthio)-1-propanal;3-(methylthio)propionaldehyde (methional)
CBNumber
CB5305315
Molecular Formula
C4H8OS
Formula Weight
104.17
MOL File
3268-49-3.mol
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3-(Methylthio)propionaldehyde Property

Melting point:
-68°C
Boiling point:
165-166 °C(lit.)
Density 
1.043 g/mL at 25 °C(lit.)
vapor density 
>1 (vs air)
vapor pressure 
760 mm Hg ( 165 °C)
FEMA 
2747 | 3-(METHYLTHIO)PROPIONALDEHYDE
refractive index 
n20/D 1.483(lit.)
Flash point:
142 °F
storage temp. 
2-8°C
solubility 
<=75g/l
form 
liquid
Odor
at 0.10 % in propylene glycol. musty potato tomato earthy vegetable creamy
Odor Type
vegetable
biological source
synthetic
explosive limit
1.3-26.1%(V)
Water Solubility 
It is readily soluble in alcohol solvents such as ethanol, propylene and glycol oil. It is insoluble in water.
Sensitive 
Air Sensitive
JECFA Number
466
BRN 
1739289
InChIKey
CLUWOWRTHNNBBU-UHFFFAOYSA-N
LogP
0.34 at 20℃
CAS DataBase Reference
3268-49-3(CAS DataBase Reference)
NIST Chemistry Reference
Propanal, 3-(methylthio)-(3268-49-3)
EPA Substance Registry System
3-(Methylthio)propanal (3268-49-3)
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Safety

Hazard Codes 
C,Xn
Risk Statements 
20/22-34-36/37/38-20-52/53-43-41-38-20/21/22
Safety Statements 
26-36/37/39-45-37/39
RIDADR 
UN 2785 6.1/PG 3
WGK Germany 
1
RTECS 
UE2285000
F 
10-13-23
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29309070
Hazardous Substances Data
3268-49-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H311Toxic in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W274711
Product name
Methional
Purity
natural, &#8805;98%, FG
Packaging
1 unit
Price
$114
Updated
2025/07/31
Sigma-Aldrich
Product number
W274711
Product name
Methional
Purity
natural, &#8805;98%, FG
Packaging
1 unit
Price
$114
Updated
2025/07/31
Sigma-Aldrich
Product number
W274711
Product name
Methional
Purity
natural, 98%, FG
Packaging
100g
Price
$962
Updated
2025/07/31
Sigma-Aldrich
Product number
W274711
Product name
Methional
Purity
natural, 98%, FG
Packaging
500g
Price
$3680
Updated
2025/07/31
Sigma-Aldrich
Product number
W274704
Product name
Methional
Purity
&#8805;97%, FG
Packaging
1 unit
Price
$56.3
Updated
2025/07/31
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3-(Methylthio)propionaldehyde Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Chemical Properties

3-(Methylthio) propionaldehyde has a powerful, onion, meat-like odor. It has a pleasant, warm, meat and soup-like flavor at low levels

Occurrence

Reported found in potato, potato chips, asparagus, tomato, tomato paste, wheat and rye bread, many cheeses, boiled egg, meats, hop oil, beer, malt whiskey, cocoa, coffee, roasted filberts and peanuts, popcorn, baked potato, cooked chicken, oatmeal, passion fruit, beans, mushroom, macadamia nut, tamarind, parsnip root, jackfruit, pumpkin, sweet corn, dried bonito, krill, shrimps, crayfish and scallops

Uses

3-Methylthiopropionaldehyde is a synthetic flavoring agent that is a colorless to light yellow liquid with an intense meat odor. it polymerizes with age and is stable in a 50% alcohol solution. it should be stored in glass containers. it is used at low concentrations for meat and broth flavors for applications in meats and condiments at 3 ppm and in baked goods and beverages at 0.5 ppm.

Uses

3-(Methylthio)propionaldehyde, is used as food flavour ,for making Baked food, spices, soft drinks, candy. It is also used as an intermediate. It has wide applications in organic synthesis as solvents as well as reagents. They are used in the synthesis of specific compound classes include agricultural chemical, property-enhancing additives, pharmacological drugs, chemical resistant polymers, detergents, and rubber antioxidants. Some examples of aliphatic and aromatic thioethers found in flavouring agents

Definition

ChEBI: 3-methylthiopropanal is an aliphatic sulfide. It has a role as a prostaglandin antagonist. It is functionally related to a propanal.

Preparation

By transamination and decarboxylation of various amino acids; by oxidation of the alcohol

Aroma threshold values

Aroma characteristics at 0.1%: vegetable oil, creamy tomato, potato skin and French fry, yeasty, bready, limburger cheese with a savory meaty brothy nuance

Taste threshold values

Taste characteristics at 5 ppb to 5 ppm: potato, musty, tomato, mold ripened cheeses, onion, beefy brothy, egg, seafood and vegetative nuances.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 1450, 1948 DOI: 10.1021/ja01184a044

General Description

A colorless to amber liquid with an extremely foul and persistent odor. Slightly soluble in water and denser than water. Contact may slightly irritate skin, eyes and mucous membranes. Moderately toxic. Used as a food additive.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Organosulfides, such as 3-(Methylthio)propionaldehyde, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid.

Health Hazard

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Taste at 0.5-1ppm

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of SOx.

Synthesis

3-(Methylthio)propionaldehyde's synthesis method is as follows: (in Nature) by transamination and decarboxylation of various amino acids

3-(Methylthio)propionaldehyde Preparation Products And Raw materials

Raw materials

3-Methylthiopropanol Acrolein Copper (II) acetate monohydrate METHYL MERCAPTAN

Preparation Products

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View Lastest Price from 3-(Methylthio)propionaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3-(Methylthio)propionaldehyde 3268-49-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-24
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-(Methylthio)propionaldehyde 3268-49-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-(Methylthio)propionaldehyde 3268-49-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

3268-49-3, 3-(Methylthio)propionaldehydeRelated Search:

Thioridazine Dimethyl sulfide Phenylpropyl aldehyde 3-Methylthiopropanol Propionaldehyde 3-METHYLOXINDOLE 96 3-(Methylthio)butanal 3-Picoline S-CARBOXYMETHYL-L-CYSTEINE LANTHIONINE 7-Aminocephalosporanic acid S-Methyl-L-cysteine 3,3'-Thiodipropionic acid Tetrahydrothiopyran-4-one Dimethyl 3,3'-thiodipropanoate Ampicillin S-Trityl-L-cysteine S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

  • C4H8SO
  • 3-Methyl propionaldehyde
  • NSC 15874
  • 3-Methyl Propionaldehyde(FEMA No.2747)
  • 3-(Methylsulfanyl)propanal
  • 3-(methylthio)-1-propanal
  • 3-(methylthio)-propana
  • 3-(methylthio)-propionaldehyd
  • 3-(methylthio)propionaldehyde (methional)
  • 3-(methylthiol)propanal
  • 3-(methythio)-propanal
  • 3-(Methylthio)propioldehyde
  • 3-Methylthiopropional
  • beta-(Methylmercapto)propionaldehyde
  • beta-(Methylthio)propionaldehyde
  • Methylmercaptopropionic aldehyde
  • methylmercaptopropionicaldehyde
  • 3-(METHYLTHIO)PROPIONALDEHYDE
  • 3-(METHYLTHIO)PROPANAL
  • 3-Methylthiopropoanaldehyde
  • 3-(METHYLMERCAPTO)PROPIONALDEHYDE
  • METHYL MERCAPTOPROPIONALDEHYDE
  • METHIONAL
  • FEMA 3174
  • FEMA 2747
  • Methional 3-(Methylmercapto)propionaldehyde 3-(Methylthio)propanal 4-Thiapentanal
  • METHIONAL(P)
  • MaleiMidopropionic acid MaleiMidoMethyl ester
  • 4-THIAPENTANAL
  • Methylmetcaptoaldehyde
  • MMP
  • Propanal,3-(methylthio)-
  • Propionaldehyde, 3-(methylthio)-
  • 3-(METHYLMERCAPTO)PROPIONALDEHYDE, MIXTU RE OF OLIGOMERS
  • 3-(Methylmercapto)propional
  • β-Methylthiopropionaldehyde
  • methional,3-(methylthio)propionaldehyde,4-thiapentanal
  • APPETAL
  • THIA-4-PENTANAL
  • 3-(METHYLTHIO)PROPIOALDEHYDE
  • 3-METHYLMERCAPTOPROPANAL
  • METHYLMERCAPTOPROPIONAL
  • 3-(METHYLTHIO)PROPIONALDEHYDE<BR> METHIONAL
  • Methylthio)propionaldehyd
  • METHIONAL, NATURAL
  • 3-(Methylmercapto)propionaldehyde, Methional
  • 3-Methylthiopropylaldehyde
  • 3-(Methyhhio)propionaldehyde
  • thio)propionaL
  • 3-Methylthio propionaldehyde >=98.0%
  • 3-(Methylthio)propionaldehyde,95%
  • 3-Methylthiopropanl
  • Methional (3-Methylthio Propionaldehyde)
  • 3-(Methylthio)propionaldehyde&gt
  • 3-(Methylthio)propionaldehyde USP/EP/BP
  • 2-hydroxy-4 - (methylthio) nitrile
  • High purity CAS 3268-49-3 3-(Methylthio)propionaldehyde in stock
  • Methional in methanol