WWL229

Product Name: WWL229
CAS No.: 1338575-28-2
Chemical Name: WWL229
Synonyms: WWL229;Reaxys ID: 25732135;WWL229, 10 mM in DMSO;XVBRVSAGMWRVCK-UHFFFAOYSA-N;WWL 229,WWL-229,Inhibitor,inhibit,WWL229;WWL229 4-Nitrophenyl 2-(3-methoxypropyl) piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 2-(3-methoxypropyl)-, 4-nitrophenyl ester
CBNumber: CB53067597
Molecular Formula: C16H22N2O5
Formula Weight: 322.36
MOL File: 1338575-28-2.mol

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WWL229 Property

storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form: oil
color: colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1180
Product name: WWL229
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $47.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1180
Product name: WWL229
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $462
Updated: 2024/03/01

Cayman Chemical

Product number: 16182
Product name: WWL229
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 16182
Product name: WWL229
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 16182
Product name: WWL229
Purity: ≥98%
Packaging: 10mg
Price: $193
Updated: 2024/03/01

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WWL229 Chemical Properties,Usage,Production

Uses

WWL229 is a selective inhibitor of Ces3 (carboxylesterase-3) which mediates triglyceride hydrolysis in white adipose tissue. Potential anti-diabetic agent.

Biological Activity

WWL229 is a highly selective inhibitor of mouse Carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes. WWL229 inhibits mCes3 with an IC50 of 10 μM, but not Ces1f, ABHD6 or other tested serine hydrolases. In a recent study, hCES1 activity was found to be increased two-fold in obese individuals and patients with type 2 diabetes compared to lean subjects, and is thought to generate surplus fatty acids th at can deposit ectopically in tissues. WWL229 inhibits adipocyte basal lipolysis and promotes differentiation and lipid storage in adipocytes.

WWL229 Preparation Products And Raw materials

Raw materials

Preparation Products

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WWL229 Suppliers

China 53 United Kingdom 1 United States 6 Global 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4569
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9805
Advantage: 58

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2951
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

1338575-28-2, WWL229Related Search:

WY-14643 Wnt-C59 Wnt Agonist WS3 WWL123 WWL113 WWL70 4-[2-(cyclopropanecarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzoic acid WWL 154

WWL229

XVBRVSAGMWRVCK-UHFFFAOYSA-N

Reaxys ID: 25732135

1-Piperidinecarboxylic acid, 2-(3-methoxypropyl)-, 4-nitrophenyl ester

WWL229 4-Nitrophenyl 2-(3-methoxypropyl) piperidine-1-carboxylate

WWL 229,WWL-229,Inhibitor,inhibit,WWL229

WWL229, 10 mM in DMSO

1338575-28-2