Wnt Agonist
- Product Name
- Wnt Agonist
- CAS No.
- 853220-52-7
- Chemical Name
- Wnt Agonist
- Synonyms
- BML;-284;AMBMP;BML-284;CS-2376;Wnt Agonist;2-Amino-4-[3;Wnt agonist 1;Wnt Agonist I;BML-284 (BML 284
- CBNumber
- CB42750501
- Molecular Formula
- C19H18N4O3
- Formula Weight
- 350.37
- MOL File
- 853220-52-7.mol
Wnt Agonist Property
- Boiling point:
- 623.4±65.0 °C(Predicted)
- Density
- 1.353±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- pka
- 6.62±0.10(Predicted)
- form
- Yellowish sticky solid
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0698
- Product name
- CID 11210285 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $119
- Updated
- 2024/03/01
- Product number
- SML0698
- Product name
- CID 11210285 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $386
- Updated
- 2024/03/01
- Product number
- 681665
- Product name
- Wnt Agonist - CAS 853220-52-7 - Calbiochem
- Purity
- The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
- Packaging
- 5mg
- Price
- $265
- Updated
- 2024/03/01
- Product number
- 19903
- Product name
- Wnt Agonist I
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 19903
- Product name
- Wnt Agonist I
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $120
- Updated
- 2024/03/01
Wnt Agonist Chemical Properties,Usage,Production
Uses
CID 11210285 hydrochloride has been used as a Wnt agonist.
Definition
ChEBI: N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine is a member of pyrimidines.
Biological Activity
wnt agonist 1 is a small-molecule agonist of wnt signaling pathway [1].the wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation [1].wnt agonist 1 is a cell-permeable wnt signaling pathway agonist. wnt agonist 1 induced b-catenin- and tcf-dependent transcriptional activity in a dose-dependent way with ec50 of 0.7 μm. in xenopus embryos, treatment with wnt agonist 1 (10 μm) from developmental stage 10.5 to stage 40 resulted in substantial head defects, such as diminished heads and complete loss of eyes, and reduced eyes and heads. this phenotype is similar to that which results from wnt over-expression in head specification during early embryonic development.
Biochem/physiol Actions
CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.
References
liu j, wu x, mitchell b, et al. a small-molecule agonist of the wnt signaling pathway. angew chem int ed engl. 2005 mar 18;44(13):1987-90.
Wnt Agonist Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Wnt Agonist manufacturers
- Product
- Wnt Agonist 853220-52-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23