ChemicalBook > CAS DataBase List > (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
- Product Name
- (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
- CAS No.
- 1638499-31-6
- Chemical Name
- (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
- Synonyms
- Tofacitinib-4;Tofatinib Impurity 35;Nicotinamide Impurity 114;3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-;(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity);Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
- CBNumber
- CB53154815
- Molecular Formula
- C14H22N2
- Formula Weight
- 218.34
- MOL File
- 1638499-31-6.mol
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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Property
- Boiling point:
- 302.6±35.0 °C(Predicted)
- Density
- 1.00±0.1 g/cm3(Predicted)
- pka
- 10.26±0.40(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- B276215
- Product name
- (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
- Packaging
- 2.5mg
- Price
- $330
- Updated
- 2021/12/16
TRC
- Product number
- B276215
- Product name
- (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine
- Packaging
- 25mg
- Price
- $2640
- Updated
- 2021/12/16
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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Chemical Properties,Usage,Production
Uses
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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1638499-31-6, (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amineRelated Search:
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3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)-
(3R,4R)-N,4-dimethyl-piperidin-3-amine
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CYANOACETIC ACID-OSU